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Publications 1969 2018

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Article
2016
17 Citations (Scopus)

Allosteric modulation of the calcium-sensing receptor rectifies signaling abnormalities associated with G-protein α-11 mutations causing hypercalcemic and hypocalcemic disorders

Babinsky, V. N., Hannan, F. M., Gorvin, C. M., Howles, S. A., Nesbit, M. A., Rust, N., Hanyaloglu, A. C., Hu, J., Spiegel, A. M. & Thakker, R. V., May 13 2016, In : Journal of Biological Chemistry. 291, 20, p. 10876-10885 10 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
GTP-Binding Proteins
Modulation
Mutation
Phosphorylation
2015

Foreword

Spiegel, A. M., Jan 1 2015, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Research in academic medical centers: Two threats to sustainable support

Levine, A. S., Alpern, R. J., Andrews, N. C., Antman, K., Balser, J. R., Berg, J. M., Davis, P. B., Fitz, J. G., Golden, R. N., Goldman, L., Jameson, J. L., Lee, V. S., Polonsky, K. S., Rappley, M. D., Reece, E. A., Rothman, P. B., Schwinn, D. A., Shapiro, L. J. & Spiegel, A. M., May 27 2015, In : Science Translational Medicine. 7, 289, 289fs22.

Research output: Contribution to journalArticle

Clinical Medicine
Biomedical Research
Research
30 Citations (Scopus)

The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing receptor (CaSR) mutation: Relevance to autosomal dominant hypocalcemia type 1 (ADH1)

Hannan, F. M., Walls, G. V., Babinsky, V. N., Nesbit, M. A., Kallay, E., Hough, T. A., Fraser, W. D., Cox, R. D., Hu, J., Spiegel, A. M. & Thakker, R. V., Sep 1 2015, In : Endocrinology. 156, 9, p. 3114-3121 8 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Hypocalcemia
Calcium
Mutation
HEK293 Cells
2013
1 Citation (Scopus)

G proteins - The disease spectrum expands

Spiegel, A. M., 2013, In : New England Journal of Medicine. 368, 26, p. 2515-2516 2 p.

Research output: Contribution to journalArticle

GTP-Binding Proteins
3 Citations (Scopus)

The stem cell wars: a dispatch from the front.

Spiegel, A. M., 2013, In : Transactions of the American Clinical and Climatological Association. 124, p. 94-110 17 p.

Research output: Contribution to journalArticle

Regenerative Medicine
Stem Cell Research
Stem Cells
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
2012
10 Citations (Scopus)
Precision Medicine
Type 2 Diabetes Mellitus
Biomarkers
Public Health
DNA
2011
2 Citations (Scopus)

Good news for advanced-stage pancreatic neuroendocrine tumors

Spiegel, A. M. & Libutti, S. K., May 2011, In : Nature Reviews Clinical Oncology. 8, 5, p. 258-259 2 p.

Research output: Contribution to journalArticle

Indoles
Pyrroles
Neuroendocrine Tumors
Pancreatic Neoplasms
Antineoplastic Agents
2010
2 Citations (Scopus)

Commentary: New guidelines for nih peer review: Improving the system or undermining it?

Spiegel, A. M., May 2010, In : Academic Medicine. 85, 5, p. 746-748 3 p.

Research output: Contribution to journalArticle

Peer Review
National Institutes of Health (U.S.)
peer review
Guidelines
health
3 Citations (Scopus)

Future diagnostic and therapeutic trends in endocrine cancers

Spiegel, A. M. & Libutti, S. K., Dec 2010, In : Seminars in Oncology. 37, 6, p. 691-695 5 p.

Research output: Contribution to journalArticle

Endocrine Gland Neoplasms
Thyroid Neoplasms
Iodine
Therapeutics
Molecular Imaging
2009
36 Citations (Scopus)

Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of men 1

Jennifer Shen, H. C., He, M., Powell, A., Adem, A., Lorang, D., Heller, C., Grover, A. C., Ylaya, K., Hewitt, S. M., Marx, S. J., Spiegel, A. M. & Libutti, S. K., Mar 1 2009, In : Cancer Research. 69, 5, p. 1858-1866 9 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia
Multiple Endocrine Neoplasia Type 1
Neuroendocrine Tumors
Islets of Langerhans
Exocrine Pancreas
2008

Albert Einstein College of Medicine.

Spiegel, A. M., May 2008, In : Academic medicine : journal of the Association of American Medical Colleges. 83, 5, p. 524 1 p.

Research output: Contribution to journalArticle

Medical Education
Medical Schools
Biomedical Research
Medicine
medicine
31 Citations (Scopus)

Parathyroid tumor development involves deregulation of homeobox genes

Shen, H. C. J., Rosen, J. E., Yang, L. M., Savage, S. A., Burns, A. L., Mateo, C. M., Agarwal, S. K., Chandrasekharappa, S. C., Spiegel, A. M., Collins, F. S., Marx, S. J. & Libutti, S. K., Mar 2008, In : Endocrine-Related Cancer. 15, 1, p. 267-275 9 p.

Research output: Contribution to journalArticle

Homeobox Genes
Multiple Endocrine Neoplasia Type 1
Neoplasms
Tumor Suppressor Genes
Developmental Genes
2007
39 Citations (Scopus)

Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation

Agarwal, S. K., Impey, S., McWeeney, S., Scacheri, P. C., Collins, F. S., Goodman, R. H., Spiegel, A. M. & Marx, S. J., Feb 2007, In : Neoplasia. 9, 2, p. 101-107 7 p.

Research output: Contribution to journalArticle

Chromatin
Multiple Endocrine Neoplasia Type 1
Genes
Genome
Chromatin Immunoprecipitation
11 Citations (Scopus)

Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca2+ receptor

Hu, J., Reyes-Cruz, G., Goldsmith, P. K., Gantt, N. M., Miller, J. L. & Spiegel, A. M., Apr 2007, In : Journal of Bone and Mineral Research. 22, 4, p. 601-608 8 p.

Research output: Contribution to journalArticle

Droseraceae
Monoclonal Antibodies
Antibodies
Takifugu
Epitopes
76 Citations (Scopus)

Parathyroid-specific double knockout of Gq and G11 α-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+-sensing receptor

Wettschureck, N., Lee, E., Libutti, S. K., Offermanns, S., Robey, P. G. & Spiegel, A. M., Jan 2007, In : Molecular Endocrinology. 21, 1, p. 274-280 7 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Phenotype
Heterotrimeric GTP-Binding Proteins
Hyperparathyroidism
Hypercalcemia
87 Citations (Scopus)
Calcium-Sensing Receptors
Modulators
G-Protein-Coupled Receptors
Mutation
Droseraceae
62 Citations (Scopus)

The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations

Ozawa, A., Agarwal, S. K., Mateo, C. M., Burns, A. L., Rice, T. S., Kennedy, P. A., Quigley, C. M., Simonds, W. F., Weinstein, L. S., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M. & Marx, S. J., May 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 5, p. 1948-1951 4 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Tumors
Mutation
Neoplasms
Germ-Line Mutation
2006
37 Citations (Scopus)

A missense mutation in the seven-transmembrane domain of the human Ca 2+ receptor converts a negative allosteric modulator into a positive allosteric modulator

Hu, J., Jiang, J., Costanzi, S., Thomas, C., Yang, W., Feyen, J. H. M., Jacobson, K. A. & Spiegel, A. M., Jul 28 2006, In : Journal of Biological Chemistry. 281, 30, p. 21558-21565 8 p.

Research output: Contribution to journalArticle

Missense Mutation
G-Protein-Coupled Receptors
Modulators
Allosteric Site
Amines
10 Citations (Scopus)

Genetic interactions between Drosophila melanogaster menin and Jun/Fos

Cerrato, A., Parisi, M., Anna, S. S., Missirlis, F., Guru, S., Agarwal, S., Sturgill, D., Talbot, T., Spiegel, A. M., Collins, F., Chandrasekharappa, S., Marx, S. & Oliver, B., Oct 1 2006, In : Developmental Biology. 298, 1, p. 59-70 12 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Proteins
Alleles
Multiple Endocrine Neoplasia
Nuclear Proteins
150 Citations (Scopus)

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.

Scacheri, P. C., Davis, S., Odom, D. T., Crawford, G. E., Perkins, S., Halawi, M. J., Agarwal, S. K., Marx, S. J., Spiegel, A. M., Meltzer, P. S. & Collins, F. S., Apr 2006, In : PLoS Genetics. 2, 4

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
tumor
carcinogenesis
Carcinogenesis
genome
8 Citations (Scopus)

NIH research on obesity and type 2 diabetes: Providing the scientific evidence base for actions to improve health

Spiegel, A. M. & Nabel, E. G., Jan 2006, In : Nature Medicine. 12, 1, p. 67-69 3 p.

Research output: Contribution to journalArticle

Physical Fitness
Health Behavior
National Institutes of Health (U.S.)
Leptin
Health Promotion
2005
74 Citations (Scopus)

A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+

Hu, J., McLarnon, S. J., Mora, S., Jiang, J., Thomas, C., Jacobson, K. A. & Spiegel, A. M., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 5113-5120 8 p.

Research output: Contribution to journalArticle

Chemical activation
Alanine
Mutation
Mutagenesis
G-Protein-Coupled Receptors
34 Citations (Scopus)
National Institutes of Health
National Institutes of Health (U.S.)
obesity
Obesity
Research
11 Citations (Scopus)

Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas

Rosen, J. E., Costouros, N. G., Lorang, D., Lee Burns, A., Alexander, H. R., Skarulis, M. C., Cochran, C., Pingpank, J. F., Marx, S. J., Spiegel, A. M. & Libutti, S. K., May 2005, In : Annals of Surgical Oncology. 12, 5, p. 1-5 5 p.

Research output: Contribution to journalArticle

Parathyroid Neoplasms
Transcriptome
Primary Hyperparathyroidism
RNA
Genes
98 Citations (Scopus)

Menin molecular interactions: Insights into normal functions and tumorigenesis

Agarwal, S. K., Kennedy, P. A., Scacheri, P. C., Novotny, E. A., Hickman, A. B., Cerrato, A., Rice, T. S., Moore, J. B., Rao, S., Ji, Y., Mateo, C., Libutti, S. K., Oliver, B., Chandrasekharappa, S. C., Burns, A. L., Collins, F. S., Spiegel, A. M. & Marx, S. J., Jun 2005, In : Hormone and Metabolic Research. 37, 6, p. 369-374 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Molecular interactions
Tumors
Carcinogenesis
Genes
123 Citations (Scopus)

National Institutes of Health Consensus Development Conference statement on Celiac Disease, June 28-30, 2004

Elson, C. O., Ballew, M., Barnard, J. A., Bernstein, S. J., Check, I. J., Cohen, M. B., Fazio, S., Johanson, J. F., Lindor, N. M., Montgomery, E., Richardson, L. H., Rogers, D., Vijan, S., Bushara, K. O., Case, S., Catassi, C., Ciclitira, P. J., Collin, P., Cranney, A., Eisenbarth, G. S. & 45 others, Fasano, A., Green, P. H. R., Hill, I. D., Hoffenberg, E. J., Kagnoff, M. F., Kelly, C. P., Kupper, C., Murray, J. A., Pietzak, M. M., Rewers, M. J., Rostom, A., Zone, J. J., James, S. P., Atkins, D., Bray, E. A., Elson, C. O., Everhart, J., Fasano, A., Gallo-Torres, H., Grave, G. D., Hamilton, F. A., Hubbard, V. S., Kagnoff, M. F., Kelly, C. P., Kramer, B. S., Marciel, K. K., Monarch, E., Murray, J. A., Nerurkar, L. S., Patrias, K., Pennington, J., Rewers, M. J., Spiegel, A. M., Rothermel, A., Siegel, J. N., Spence, J. T., Willard, C., Wilson, W., Spiegel, A. M., Kramer, B. S., Crawford, L. M., Veneman, A. M., Alexander, D., Von Eschenbach, A. C. & Fauci, A. S., Apr 2005, In : Gastroenterology. 128, 4 SUPPL. 1

Research output: Contribution to journalArticle

Consensus Development Conferences
National Institutes of Health (U.S.)
Celiac Disease
Federal Government
Health Services Research
27 Citations (Scopus)

Obesity on the brain

Spiegel, A. M., Nabel, E., Volkow, N., Landis, S. & Li, T. K., May 2005, In : Nature Neuroscience. 8, 5, p. 552-553 2 p.

Research output: Contribution to journalArticle

Prenatal Exposure Delayed Effects
Interdisciplinary Communication
Addictive Behavior
Appetite Regulation
Neural Pathways
2004
24 Citations (Scopus)

Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor

Hu, J., Mora, S., Weber, G., Zamproni, I., Proverbio, M. C. & Spiegel, A. M., Apr 2004, In : Journal of Bone and Mineral Research. 19, 4, p. 578-586 9 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Monozygotic Twins
Germ-Line Mutation
Siblings
Hypocalcemia
7 Citations (Scopus)

Focus on hereditary endocrine neoplasia

Spiegel, A. M., Oct 2004, In : Cancer Cell. 6, 4, p. 327-332 6 p.

Research output: Contribution to journalArticle

Endocrine Gland Neoplasms
Polyostotic Fibrous Dysplasia
von Hippel-Lindau Disease
Paraganglioma
Hyperparathyroidism
42 Citations (Scopus)

Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1

Scacheri, P. C., Crabtree, J. S., Kennedy, A. L., Swain, G. P., Ward, J. M., Marx, S. J., Spiegel, A. M. & Collins, F. S., Nov 2004, In : Mammalian Genome. 15, 11, p. 872-877 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Liver
Neoplasms
Organ Specificity
Tumor Suppressor Genes
180 Citations (Scopus)

Inherited diseases involving G proteins and G protein-coupled receptors

Spiegel, A. M. & Weinstein, L. S., 2004, In : Annual Review of Medicine. 55, p. 27-39 13 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
GTP-Binding Proteins
Gene encoding
Heterotrimeric GTP-Binding Proteins
Mutation
116 Citations (Scopus)

Molecular pathology of the MEN1 gene

Agarwal, S. K., Burns, A. L., Sukhodolets, K. E., Kennedy, P. A., Obungu, V. H., Hickman, A. B., Mullendore, M. E., Whitten, I., Skarulis, M. C., Simonds, W. F., Mateo, C., Crabtree, J. S., Scacheri, P. C., Ji, Y., Novotny, E. A., Garrett-Beal, L., Ward, J. M., Libutti, S. K., Alexander, H. R., Cerrato, A. & 7 others, Parisi, M. J., Anna-A, S. S., Oliver, B., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M. & Marx, S. J., 2004, In : Annals of the New York Academy of Sciences. 1014, p. 189-198 10 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Molecular Pathology
Pathology
Tumors
Genes
20 Citations (Scopus)

Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability

Scacheri, P. C., Kennedy, A. L., Chin, K., Miller, M. T., Hodgson, J. G., Gray, J. W., Marx, S. J., Spiegel, A. M. & Collins, F. S., Oct 1 2004, In : Cancer Research. 64, 19, p. 7039-7044 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Chromosomal Instability
Microsatellite Instability
Insulinoma
Knockout Mice
2003
GTP-Binding Proteins
106 Citations (Scopus)
Droseraceae
Calcium-Sensing Receptors
Mutation
G-Protein-Coupled Receptors
158 Citations (Scopus)

Of mice and MEN1: Insulinomas in a conditional mouse knockout

Crabtree, J. S., Scacheri, P. C., Ward, J. M., McNally, S. R., Swain, G. P., Montagna, C., Hager, J. H., Hanahan, D., Edlund, H., Magnuson, M. A., Garrett-Beal, L., Burns, A. L., Ried, T., Chandrasekharappa, S. C., Marx, S. J., Spiegel, A. M. & Collins, F. S., Sep 2003, In : Molecular and Cellular Biology. 23, 17, p. 6075-6085 11 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Insulinoma
Knockout Mice
Islets of Langerhans
Adenoma
70 Citations (Scopus)

Parathyroid Gland-specific Deletion of the Mouse Men1 Gene Results in Parathyroid Neoplasia and Hypercalcemic Hyperparathyroidism

Libutti, S. K., Crabtree, J. S., Lorang, D., Burns, A. L., Mazzanti, C., Hewitt, S. M., O'Connor, S., Ward, J. M., Emmert-Buck, M. R., Remaley, A., Miller, M., Turner, E., Alexander, H. R., Arnold, A., Marx, S. J., Collins, F. S. & Spiegel, A. M., Nov 15 2003, In : Cancer Research. 63, 22, p. 8022-8028 7 p.

Research output: Contribution to journalArticle

Parathyroid Glands
Hyperparathyroidism
Gene Deletion
Multiple Endocrine Neoplasia Type 1
Hypercalcemia
99 Citations (Scopus)

The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene

Sukhodolets, K. E., Hickman, A. B., Agarwal, S. K., Sukhodolets, M. V., Obungu, V. H., Novotny, E. A., Crabtree, J. S., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M., Burns, A. L. & Marx, S. J., Jan 2003, In : Molecular and Cellular Biology. 23, 2, p. 493-509 17 p.

Research output: Contribution to journalArticle

Replication Protein A
Multiple Endocrine Neoplasia Type 1
Tumor Suppressor Genes
Two-Hybrid System Techniques
Proteins
95 Citations (Scopus)

Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter

Agarwal, S. K., Novotny, E. A., Crabtree, J. S., Weitzman, J. B., Yaniv, M., Burns, A. L., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M. & Marx, S. J., Sep 16 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 19, p. 10770-10775 6 p.

Research output: Contribution to journalArticle

Transcription Factors
Fibroblasts
Growth
Cell Proliferation
Multiple Endocrine Neoplasia Type 1
12 Citations (Scopus)

β-arrestin - Not just for G protein-coupled receptors

Spiegel, A. M., Sep 5 2003, In : Science. 301, 5638, p. 1338-1339 2 p.

Research output: Contribution to journalArticle

Cell-Membrane Coated Pits
Signal Transducing Adaptor Proteins
Proto-Oncogene Proteins
Arrestins
Wnt Proteins
2002
22 Citations (Scopus)

Autosomal dominant hypocalcemia caused by a novel mutation in the loop 2 region of the human calcium receptor extracellular domain

Hu, J., Mora, S., Colussi, G., Proverbio, M. C., Jones, K. A., Bolzoni, L., De Ferrari, M. E., Civati, G. & Spiegel, A. M., 2002, In : Journal of Bone and Mineral Research. 17, 8, p. 1461-1469 9 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Mutation
HEK293 Cells
Missense Mutation
Phosphatidylinositols
127 Citations (Scopus)

Hyperparathyroidism in hereditary syndromes: Special expressions and special managements

Marx, S. J., Simonds, W. F., Agarwal, S. K., Burns, A. L., Weinstein, L. S., Cochran, C., Skarulis, M. C., Spiegel, A. M., Libutti, S. K., Alexander, H. R., Chen, C. C., Chang, R., Chandrasekharappa, S. C. & Collins, F. S., Nov 1 2002, In : Journal of Bone and Mineral Research. 17, SUPPL. 2

Research output: Contribution to journalArticle

Hyperparathyroidism
Parathyroidectomy
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia Type 1
Neoplasms
78 Citations (Scopus)
N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine
Modulators
Chemical activation
Alanine
Mutation
2001
342 Citations (Scopus)

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

Crabtree, J. S., Scacheri, P. C., Ward, J. M., Garrett-Beal, L., Emmert-Buck, M. R., Edgemon, K. A., Lorang, D., Libutti, S. K., Chandrasekharappa, S. C., Marx, S. J., Spiegel, A. M. & Collins, F. S., Jan 30 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 3, p. 1118-1123 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Neoplasms
Islets of Langerhans
Islet Cell Adenoma
Alleles
68 Citations (Scopus)

Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice

Scacheri, P. C., Crabtree, J. S., Novotny, E. A., Garrett-Beal, L., Chen, A., Edgemon, K. A., Marx, S. J., Spiegel, A. M., Chandrasekharappa, S. C. & Collins, F. S., 2001, In : Genesis. 30, 4, p. 259-263 5 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Neomycin
Heterozygote
Knockout Mice
Embryonic Structures
30 Citations (Scopus)

Characterization of a MEN1 ortholog from Drosophila melanogaster

Guru, S. C., Prasad, N. B., Shin, E. J., Hemavathy, K., Lu, J., Ip, Y. T., Agarwal, S. K., Marx, S. J., Spiegel, A. M., Collins, F. S., Oliver, B. & Chandrasekharappa, S. C., Jan 24 2001, In : Gene. 263, 1-2, p. 31-38 8 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Drosophila melanogaster
Drosophila
Amino Acids
Polyadenylation
29 Citations (Scopus)

Human Ca2+ receptor extracellular domain. Analysis of function of lobe I loop deletion mutants

Reyes-Cruz, G., Hu, J., Goldsmith, P. K., Steinbach, P. J. & Spiegel, A. M., Aug 24 2001, In : Journal of Biological Chemistry. 276, 34, p. 32145-32151 7 p.

Research output: Contribution to journalArticle

Droseraceae
Periplasmic Binding Proteins
Bacterial Proteins
Chemical activation
G-Protein-Coupled Receptors
145 Citations (Scopus)

Multiple endocrine neoplasia type 1: New clinical and basic findings

Schussheim, D. H., Skarulis, M. C., Agarwal, S. K., Simonds, W. F., Burns, A. L., Spiegel, A. M. & Marx, S. J., 2001, In : Trends in Endocrinology and Metabolism. 12, 4, p. 173-178 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Neoplasms
Mutation
Carcinoid Tumor
Rare Diseases
10 Citations (Scopus)

Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor

Valle, M. A., Kester, M. B., Burns, A. L., Marx, S. J., Spiegel, A. M. & Shiloach, J., 2001, In : Cytotechnology. 35, 2, p. 127-135 9 p.

Research output: Contribution to journalArticle

Drosophila melanogaster
Purification
Copper Sulfate
Copper
Metallothionein