• 12601 Citations
  • 60 h-Index
1960 …2023
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  • 3 Similar Profiles
Antibodies Medicine & Life Sciences
Immunoglobulins Medicine & Life Sciences
Monoclonal Antibodies Medicine & Life Sciences
Cryptococcus neoformans Medicine & Life Sciences
Mutation Medicine & Life Sciences
Hybridomas Medicine & Life Sciences
Immunoglobulin Genes Medicine & Life Sciences
Immunoglobulin G Medicine & Life Sciences

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Grants 1977 2023

Mutation
Antibodies
Genes
Databases
Immunoglobulin Variable Region

CANCER RESEARCH CENTER

Brewer, C. F., Bases, R., Kadish, A., Wiernik, P., Orr, G., Bloom, B., Shapiro, L., Lilly, F., Chase, J., Atkinson, P., Maio, J., Reid, L., Levine, W., Nathenson, S., Fant, J., Warner, J., Peisach, J., Horwitz, M., Krauter, K., Makman, M., Blumenfeld, O., Schulman, L., Klinger, H., Rajan, T., Wadler, S., Chance, M., Buhl, S., Desai, K., Pollard, J. W., Brenowitz, M. D., Stanley, P., Skoultchi, A. I., Sparano, J. A., Hurwitz, J., Duran-Reynals, M., Serrano, L., Alderman, M., Shin, S., West, M., Birshstein, B., Marians, K., Eagle, H., Russel, R., Grills, G., Pickering, K., Mahmood, R., Keller, S. M., Herbst, L., Seither, R., Satir, B. H., Rubin, C. S., Scharff, M. D., Maitra, U., Band Horwitz, S., Schildkraut, C. L., Ho, G. Y. F., Cannizzaro, L. A., Childs, G. J., Augenlicht, L. H., Almo, S. C., Greally, J. M., Angeletti, R. H., Porcelli, S. A., Morrow, B. E., Condeelis, J. S., Montagna, C., Edelmann, W., Kim, M., Rohan, T. E., Goldman, I. D., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Keller, S. M., Pollard, J. W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J. & Keller, S. M.

National Institutes of Health

6/1/776/30/19

Project: Research projectCenter Core Grants

Research Personnel
Organized Financing
Neoplasms
Research
Medical Oncology

Northeast Biodefense Center

Scharff, M. D., Palacios, G. F., Basler, C., Alaedini, A., Fries, B., Briese, T., Rice, C., [No Value], C. R., Chave, K. J., Bliska, J., Brady, S., Rose, J. K., Garcia-Sastre, A., Gulcicek, E., Perlin, D., Moscona, A., Palese, P., Lipkin, W., Califano, A., Buck, J., Belfort, M., Pei-Yong, S., Crystal, R., Severinov, K., Sturman, L., Bernard, K., Galan, J., MacKow, E. R., Egan, C., Kielian, M., Casadevall, A., Levy, D., Palacios, G. F., [No Value], C. R., Lipkin, W., Rose, J. K. & MacKow, E. R.

National Institutes of Health

9/4/032/28/15

Project: Research projectSpecialized Center--Cooperative Agreements

Chikungunya virus
Prostaglandins A
Anthrax
Dengue Virus
Passive Immunization
DNA Mismatch Repair
Immunoglobulin Class Switching
Mutation
B-Lymphocytes
Antibodies
Immunoglobulin Class Switching
DNA Mismatch Repair
Mutation
Immunoglobulin Genes
Genetic Recombination

Publications 1960 2018

  • 12601 Citations
  • 60 h-Index
  • 262 Article
  • 4 Chapter
  • 1 Conference contribution

Human immunodeficiency virus tat protein aids V region somatic hypermutation in human B cells

Wang, X., Duan, Z., Yu, G., Fan, M. & Scharff, M. D., Mar 1 2018, In : mBio. 9, 2, e02315-17.

Research output: Contribution to journalArticle

tat Gene Products
Human Immunodeficiency Virus Proteins
B-Lymphocytes
HIV
Virus Diseases

Error-Prone Mismatch and Base Excision DNA Repair in Somatic Hypermutation

Wang, S., Chahwan, R., Wei, L. & Scharff, M. D., Apr 27 2016, Molecular Immunology. Elsevier Inc., Vol. 2. p. 126-133 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA Repair
Antibodies
V(D)J Recombination
Genetic Recombination
B-Lymphocytes
19 Citations

Overlapping hotspots in CDRs are critical sites for V region diversification

Wei, L., Chahwan, R., Wang, S., Wang, X., Pham, P. T., Goodman, M. F., Bergman, A., Scharff, M. D. & MacCarthy, T., Feb 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E728-E737

Research output: Contribution to journalArticle

Mutation
B-Lymphocytes
Immunoglobulin Variable Region
High-Throughput Nucleotide Sequencing
Mutation Rate
17 Citations

A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation

Wang, X., Fan, M., Kalis, S., Wei, L. & Scharff, M. D., Jun 13 2014, In : Nature Communications. 5, 4137.

Research output: Contribution to journalArticle

Immunoglobulin Heavy Chains
Single-Stranded DNA
Transcription
deoxyribonucleic acid
activation
12 Citations

Detection and measurement of staphylococcal enterotoxin-like K (SEl-K) secretion by Staphylococcus aureus clinical isolates

Aguilar, J. L., Varshney, A. K., Wang, X., Stanford, L., Scharff, M. & Fries, B. C., 2014, In : Journal of Clinical Microbiology. 52, 7, p. 2536-2543 8 p.

Research output: Contribution to journalArticle

Enterotoxins
Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
Enzyme-Linked Immunosorbent Assay
Genes