Projects per year
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Grants
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Mismatch repair in V region mutation and isotype switching
Scharff, M. D. & Rose, S. A.
National Institute of Allergy and Infectious Diseases
8/11/14 → 7/31/19
Project: Research project
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Northeast Biodefense Center
Scharff, M. D., Palacios, G. F., Basler, C., Alaedini, A., Fries, B., Briese, T., Rice, C., [No Value], C. R., Chave, K. J., Bliska, J., Brady, S., Rose, J. K., Garcia-Sastre, A., Gulcicek, E., Perlin, D., Moscona, A., Palese, P., Lipkin, W., Califano, A., Buck, J., Belfort, M., Pei-Yong, S., Crystal, R., Severinov, K., Sturman, L., Bernard, K., Galan, J., MacKow, E. R., Egan, C., Casadevall, A., Levy, D., Palacios, G. F., [No Value], C. R., Lipkin, W., Rose, J. K. & MacKow, E. R.
3/1/08 → 2/28/09
Project: Research project
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Mismatch Repair in V region mutation and isotype switch
Scharff, M. D. & Rose, S. A.
7/1/03 → 7/31/14
Project: Research project
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The Production of More Effective Monoclonal Antibodies
National Institute of Allergy and Infectious Diseases
9/1/02 → 8/31/05
Project: Research project
Publications
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AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes
Tang, C., Bagnara, D., Chiorazzi, N., Scharff, M. D. & MacCarthy, T., Apr 30 2020, In: Frontiers in immunology. 11, 788.Research output: Contribution to journal › Article › peer-review
Open Access -
CLL intraclonal fractions exhibit established and recently acquired patterns of DNA methylation
Bartholdy, B. A., Wang, X., Yan, X. J., Pascual, M., Fan, M., Barrientos, J., Allen, S. L., Martinez-Climent, J. A., Rai, K. R., Chiorazzi, N., Scharff, M. D. & Roa, S., Mar 10 2020, In: Blood Advances. 4, 5, p. 893-906 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Human immunodeficiency virus tat protein aids V region somatic hypermutation in human B cells
Wang, X., Duan, Z., Yu, G., Fan, M. & Scharff, M. D., Mar 1 2018, In: mBio. 9, 2, e02315-17.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Error-Prone Mismatch and Base Excision DNA Repair in Somatic Hypermutation
Wang, S., Chahwan, R., Wei, L. & Scharff, M. D., Apr 27 2016, Molecular Immunology. Elsevier Inc., Vol. 2. p. 126-133 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Overlapping hotspots in CDRs are critical sites for V region diversification
Wei, L., Chahwan, R., Wang, S., Wang, X., Pham, P. T., Goodman, M. F., Bergman, A., Scharff, M. D. & MacCarthy, T., Feb 17 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E728-E737Research output: Contribution to journal › Article › peer-review
27 Scopus citations