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Dive into the research topics where Matthew D. Scharff is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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A combined computational and experimental approach to the evolution and role of the DNA sequence environment in targeting mutations to antibody V regions
Scharff, M. D., MacCarthy, T. & Scharff, M. D.
National Institute of Allergy and Infectious Diseases
3/1/18 → 2/28/23
Project: Research project
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Antigen specific strategies for treatment of HIV+ cancer patients in the Montefiore/Einstein Cancer Center Catchment Area (Immuno/microenvironment)
Almo, S. C., Hogue-Angeletti, R., Augenlicht, L. H., Condeelis, J. S., Desai, K., Edelmann, W., Goldman, I. D., Greally, J. M., Herbst, L. H., Keller, S. M., Kim, M. Y., Mahmood, R., Montagna, C., Morrow, B. E., Pollard, J. W., Porcelli, S. A., Rohan, T. E., Scharff, M. D., Seither, R., Skoultchi, A. I., Sparano, J. A., Stanley, P. M., Chu, E. E., Bresnick, A. A. R., Skoultchi, A. A. I., Beck, A. A. P., Beck, A. P., Morrow, B. B. E., Blanchard, J. S., Bresnick, A. R., Morrow, B. E., Diamond, B. B., Rapkin, B. B. D., Chu, E., Montagna, C., Stein, D. D. T., Gaertner, D. D. J., Chu, E. E., Ho, G. G. Y., Goel, S., Strickler, H., Goldman, I. I. D., Pollard, J. J. W., Condeelis, J. J. S., Dutcher, J. J. P., Greally, J. M., Blanchard, J. S., Sparano, J. J. A., Desai, K. K., Herbst, L. L. H., Augenlicht, L. H., Cannizzaro, L. A., Scharff, M. M. D., Brenowitz, M. D., Kim, M. M. Y., Stanley, P., Mahmood, R. R., Gupta, R. R. K., Rapkin, B. D., Depinho, R. R. A., Angeletti, R. R. H., Kucherlapati, R. R. S., Goel, S. S., Schramm, V. L., Sparano, J. A., Steidl, U. G., Stein, D. T., Almo, S. S. C., Keller, S. S. M., Strickler, H. D., Almo, S. S., Porcelli, S. S. A., Rohan, T. E., Steidl, U. U. G., Edelmann, W. W., Xue, X. X. N., Xue, X. N., Alderman, M. H., Atkinson, P. H., Bases, R. E., Birshstein, B. K., Bloom, B. R., Blumenfeld, O. O., Brenowitz, M. D., Brewer, F. C., Buhl, S., Cannizzaro, L. A., Chance, M. R., Chase, J. W., Childs, G. J., Depinho, R., Depinho, R. A., Diamond, B. A., Diamond, B., Duran-reynals, M. L., Dutcher, J. P., Eagle, H., Fant, J., Gaertner, D. J., Grills, G., Gupta, R. K., Ho, G. Y., Band Horwitz, S., Horwitz, M. S., Hurwitz, J., Kadish, A. S., Klinger, H. P., Krauter, K. S., Kucherlapati, R. S., Levine, W. G., Lilly, F., Maio, J. J., Maitra, U., Makman, M. H., Marians, K. J., Nathenson, S. G., Orr, G. A., Peisach, J., Pickering, K., Rajan, T. V., Reid, L. M., Rubin, C. S., Russel, R., Satir, B. H., Schildkraut, C. L., Schulman, L. H., Serrano, L. J., Shapiro, L., Shin, S., Wadler, S. H., Warner, J. R., West, M. & Wiernik, P. H.
6/1/85 → 6/30/23
Project: Research project
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Mismatch repair in V region mutation and isotype switching
Scharff, M. D. & Rose, S. A.
8/11/14 → 7/31/19
Project: Research project
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Mismatch repair in V region mutation and isotype switching
Scharff, M. D. & Scharff, M. D.
National Institute of Allergy and Infectious Diseases
8/11/14 → 7/31/19
Project: Research project
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Correction to: Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells (Molecular Medicine, (2011), 17, 11-12, (1374-1382), 10.2119/molmed.2011.00360)
Calissano, C., Damle, R. N., Marsilio, S., Yan, X. J., Yancopoulos, S., Hayes, G., Emson, C., Murphy, E. J., Hellerstein, M. K., Sison, C., Kaufman, M. S., Kolitz, J. E., Allen, S. L., Rai, K. R., Ivanovic, I., Dozmorov, I. M., Roa, S., Scharff, M. D., Li, W. & Chiorazzi, N., Dec 2022, In: Molecular Medicine. 28, 1, 35.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173Amice
Wang, S., Lee, K., Gray, S., Zhang, Y., Tang, C., Morrish, R. B., Tosti, E., Van Oers, J., Amin, M. R., Cohen, P. E., MacCarthy, T., Roa, S., Scharff, M. D., Edelmann, W. & Chahwan, R., Aug 12 2022, In: Nucleic acids research. 50, 14, p. 8093-8106 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Bayesian model based computational analysis of the relationship between bisulfite accessible single-stranded DNA in chromatin and somatic hypermutation of immunoglobulin genes
Yu, G., Wu, Y., Duan, Z., Tang, C., Xing, H., Scharff, M. D. & MacCarthy, T., Sep 2021, In: PLoS Computational Biology. 17, 9, e1009323.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course
Bagnara, D., Tang, C., Brown, J. R., Kasar, S., Fernandes, S., Colombo, M., Vergani, S., Mazzarello, A. N., Ghiotto, F., Bruno, S., Morabito, F., Rai, K. R., Kolitz, J. E., Barrientos, J. C., Allen, S. L., Fais, F., Scharff, M. D., MacCarthy, T. & Chiorazzi, N., May 25 2021, In: Frontiers in Oncology. 11, 640731.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes
Duan, Z., Baughn, L. B., Wang, X., Zhang, Y., Gupta, V., MacCarthy, T., Scharff, M. D. & Yu, G., Jul 20 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2104013118.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations