• 12926 Citations
  • 61 h-Index
1960 …2023
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Fingerprint Dive into the research topics where Matthew D. Scharff is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Antibodies Medicine & Life Sciences
Immunoglobulins Medicine & Life Sciences
Monoclonal Antibodies Medicine & Life Sciences
Cryptococcus neoformans Medicine & Life Sciences
Hybridomas Medicine & Life Sciences
Immunoglobulin Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Immunoglobulin G Medicine & Life Sciences

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Grants 1977 2023

Northeast Biodefense Center

Scharff, M. D., Palacios, G. F., Basler, C., Alaedini, A., Fries, B., Briese, T., Rice, C., [No Value], C. R., Chave, K. J., Bliska, J., Brady, S., Rose, J. K., Garcia-Sastre, A., Gulcicek, E., Perlin, D., Moscona, A., Palese, P., Lipkin, W., Califano, A., Buck, J., Belfort, M., Pei-Yong, S., Crystal, R., Severinov, K., Sturman, L., Bernard, K., Galan, J., MacKow, E. R., Egan, C., Kielian, M., Casadevall, A., Levy, D., Palacios, G. F., [No Value], C. R., Lipkin, W., Rose, J. K. & MacKow, E. R.

National Institutes of Health


Project: Research project

Chikungunya virus
Prostaglandins A
Dengue Virus
Passive Immunization
Immunoglobulin Class Switching
DNA Mismatch Repair
Immunoglobulin Genes
Genetic Recombination
DNA Mismatch Repair
Immunoglobulin Class Switching
Monoclonal Antibodies
Immunoglobulin Class Switching

Publications 1960 2018

  • 12926 Citations
  • 61 h-Index
  • 262 Article
  • 4 Chapter
  • 1 Conference contribution

Human immunodeficiency virus tat protein aids V region somatic hypermutation in human B cells

Wang, X., Duan, Z., Yu, G., Fan, M. & Scharff, M. D., Mar 1 2018, In : mBio. 9, 2, e02315-17.

Research output: Contribution to journalArticle

tat Gene Products
Human Immunodeficiency Virus Proteins
Virus Diseases

Error-Prone Mismatch and Base Excision DNA Repair in Somatic Hypermutation

Wang, S., Chahwan, R., Wei, L. & Scharff, M. D., Apr 27 2016, Molecular Immunology. Elsevier Inc., Vol. 2. p. 126-133 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA Repair
V(D)J Recombination
Genetic Recombination
23 Citations (Scopus)

Overlapping hotspots in CDRs are critical sites for V region diversification

Wei, L., Chahwan, R., Wang, S., Wang, X., Pham, P. T., Goodman, M. F., Bergman, A., Scharff, M. D. & MacCarthy, T., Feb 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E728-E737

Research output: Contribution to journalArticle

Immunoglobulin Variable Region
High-Throughput Nucleotide Sequencing
Mutation Rate
18 Citations (Scopus)

A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation

Wang, X., Fan, M., Kalis, S., Wei, L. & Scharff, M. D., Jun 13 2014, In : Nature Communications. 5, 4137.

Research output: Contribution to journalArticle

Immunoglobulin Heavy Chains
Single-Stranded DNA
deoxyribonucleic acid
14 Citations (Scopus)

Detection and measurement of staphylococcal enterotoxin-like K (SEl-K) secretion by Staphylococcus aureus clinical isolates

Aguilar, J. L., Varshney, A. K., Wang, X., Stanford, L., Scharff, M. D. & Fries, B. C., 2014, In : Journal of Clinical Microbiology. 52, 7, p. 2536-2543 8 p.

Research output: Contribution to journalArticle

Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
Enzyme-Linked Immunosorbent Assay