Matthew D. Scharff, M.D.

Cell Biology

Phone718-430-3527
Emailmatthew.scharff@einsteinmed.org
Websitehttp://www.einstein.yu.edu/faculty/1450/matthew-scharff/

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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2 Active
10 Finished

A combined computational and experimental approach to the evolution and role of the DNA sequence environment in targeting mutations to antibody V regions
Scharff, M. D.
National Institute of Allergy and Infectious Diseases
3/1/18 → 2/28/22
Project: Research project
CORE--ANALYTICAL ULTRASTRUCTURE CENTER
Bases, R., Kadish, A., Wiernik, P., Orr, G., Bloom, B., Shapiro, L., Lilly, F., Chase, J., Atkinson, P., Maio, J., Reid, L., Levine, W., Nathenson, S., Fant, J., Warner, J., Peisach, J., Horwitz, M., Krauter, K., Makman, M., Blumenfeld, O., Schulman, L., Klinger, H., Rajan, T., Wadler, S., Chance, M., Buhl, S., Desai, K., Pollard, J. W., Sparano, J. A., Hurwitz, J., Duran-Reynals, M., Serrano, L., Alderman, M., Shin, S., West, M., Birshstein, B., Marians, K., Eagle, H., Russel, R., Grills, G., Pickering, K., Mahmood, R., Keller, S. M., Herbst, L., Seither, R., Condeelis, J. S., Edelmann, W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Keller, S. M., Pollard, J. W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Herbst, L. H., Goel, S., Scharff, M. D., Scharff, M. D., Scharff, M. D., Band Horwitz, S., Rubin, C. S., Schildkraut, C. L., Band Horwitz, S., Rubin, C. S., Schildkraut, C. L., Maitra, U., Satir, B. H., Cannizzaro, L. A., Cannizzaro, L. A., Childs, G. J., Childs, G. J., Skoultchi, A. I., Rohan, T. E., Porcelli, S. A., Montagna, C., Keller, S. M., Greally, J. M., Stanley, P., Beck, A. P., Steidl, U. G., Strickler, H., Rapkin, B. D. & Sparano, J. A.
National Cancer Institute
1/1/01 → 6/30/21
Project: Research project
Mismatch repair in V region mutation and isotype switching
Scharff, M. D. & Rose, S. A.
National Institute of Allergy and Infectious Diseases
8/11/14 → 7/31/19
Project: Research project
Northeast Biodefense Center
Scharff, M. D., Palacios, G. F., Basler, C., Alaedini, A., Fries, B., Briese, T., Rice, C., [No Value], C. R., Chave, K. J., Bliska, J., Brady, S., Rose, J. K., Garcia-Sastre, A., Gulcicek, E., Perlin, D., Moscona, A., Palese, P., Lipkin, W., Califano, A., Buck, J., Belfort, M., Pei-Yong, S., Crystal, R., Severinov, K., Sturman, L., Bernard, K., Galan, J., MacKow, E. R., Egan, C., Casadevall, A., Levy, D., Palacios, G. F., [No Value], C. R., Lipkin, W., Rose, J. K. & MacKow, E. R.
3/1/08 → 2/28/09
Project: Research project
Mismatch Repair in V region mutation and isotype switch
Scharff, M. D. & Rose, S. A.
National Cancer Institute
7/1/03 → 7/31/14
Project: Research project

13498 Citations
62 h-Index
228 Article
25 Review article
6 Comment/debate
5 Chapter
More

AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes
Tang, C., Bagnara, D., Chiorazzi, N., Scharff, M. D. & MacCarthy, T., Apr 30 2020, In: Frontiers in immunology. 11, 788.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
CLL intraclonal fractions exhibit established and recently acquired patterns of DNA methylation
Bartholdy, B. A., Wang, X., Yan, X. J., Pascual, M., Fan, M., Barrientos, J., Allen, S. L., Martinez-Climent, J. A., Rai, K. R., Chiorazzi, N., Scharff, M. D. & Roa, S., Mar 10 2020, In: Blood Advances. 4, 5, p. 893-906 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Human immunodeficiency virus tat protein aids V region somatic hypermutation in human B cells
Wang, X., Duan, Z., Yu, G., Fan, M. & Scharff, M. D., Mar 1 2018, In: mBio. 9, 2, e02315-17.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Error-Prone Mismatch and Base Excision DNA Repair in Somatic Hypermutation
Wang, S., Chahwan, R., Wei, L. & Scharff, M. D., Apr 27 2016, Molecular Immunology. Elsevier Inc., Vol. 2. p. 126-133 8 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter
Overlapping hotspots in CDRs are critical sites for V region diversification
Wei, L., Chahwan, R., Wang, S., Wang, X., Pham, P. T., Goodman, M. F., Bergman, A., Scharff, M. D. & MacCarthy, T., Feb 17 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E728-E737
Research output: Contribution to journal › Article › peer-review
31 Scopus citations