• 13071 Citations
  • 61 h-Index
1960 …2023

Research output per year

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Review article
2013

AID and Apobec3G haphazard deamination and mutational diversity

Jaszczur, M., Bertram, J. G., Pham, P., Scharff, M. D. & Goodman, M. F., Sep 1 2013, In : Cellular and Molecular Life Sciences. 70, 17, p. 3089-3108 20 p.

Research output: Contribution to journalReview article

19 Scopus citations
2012

AIDing antibody diversity by error-prone mismatch repair

Chahwan, R., Edelmann, W., Scharff, M. D. & Roa, S., Aug 1 2012, In : Seminars in Immunology. 24, 4, p. 293-300 8 p.

Research output: Contribution to journalReview article

43 Scopus citations
2008

Human recombinant Fab fragments with sub-nanomolar affinities for acetylated histones

Batova, I., Kowal, C., May, R., Scharff, M. D. & Diamond, B., Jan 1 2008, In : Journal of Immunological Methods. 329, 1-2, p. 1-10 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

The biochemistry of somatic hypermutation

Peled, J. U., Fei, L. K., Iglesias-Ussel, M. D., Roa, S., Kalis, S. L., Goodman, M. F. & Scharff, M. D., May 5 2008, In : Annual Review of Immunology. 26, p. 481-511 31 p.

Research output: Contribution to journalReview article

323 Scopus citations
2005

Identifying protein-protein interactions in somatic hypermutation

Goodman, M. F. & Scharff, M. D., Feb 21 2005, In : Journal of Experimental Medicine. 201, 4, p. 493-496 4 p.

Research output: Contribution to journalReview article

5 Scopus citations
2004

The generation of antibody diversity through somatic hypermutation and class switch recombination

Li, Z., Woo, C. J., Iglesias-Ussel, M. D., Ronai, D. & Scharff, M. D., Jan 1 2004, In : Genes and Development. 18, 1, p. 1-11 11 p.

Research output: Contribution to journalReview article

205 Scopus citations

The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies

Luo, Z., Ronai, D. & Scharff, M. D., Oct 2004, In : Journal of Allergy and Clinical Immunology. 114, 4, p. 726-735 10 p.

Research output: Contribution to journalReview article

21 Scopus citations
2002

Aid and mismatch repair in antibody diversification

Martin, A. & Scharff, M. D., Aug 2002, In : Nature Reviews Immunology. 2, 8, p. 605-614 10 p.

Research output: Contribution to journalReview article

102 Scopus citations
1998

Immunoglobulin hypermutation in cultured cells

Green, N. S., Lin, M. M. & Scharff, M. D., Apr 1 1998, In : Immunological Reviews. 162, p. 77-87 11 p.

Research output: Contribution to journalReview article

14 Scopus citations

Somatic hypermutation, transcription, and DNA mismatch repair

Wiesendanger, M., Scharff, M. D. & Edelmann, W., Aug 21 1998, In : Cell. 94, 4, p. 415-418 4 p.

Research output: Contribution to journalReview article

Open Access
40 Scopus citations

Somatic hypermutation of antibody genes: A hot spot warms up

Green, N. S., Lin, M. M. & Scharff, M. D., Mar 1 1998, In : BioEssays. 20, 3, p. 227-234 8 p.

Research output: Contribution to journalReview article

20 Scopus citations
1992

The role of somatic mutation in the pathogenic anti-DNA response

Diamond, B., Katz, J. B., Paul, E., Aranow, C., Lustgarten, D. & Scharff, M. D., Jun 5 1992, In : Annual Review of Immunology. 10, p. 731-757 27 p.

Research output: Contribution to journalReview article

209 Scopus citations
1989

The role of somatic hypermutation in the generation of antibody diversity

French, D. L., Laskov, R. & Scharff, M. D., Jan 1 1989, In : Science. 244, 4909, p. 1152-1157 6 p.

Research output: Contribution to journalReview article

225 Scopus citations
1986

Tailor-made monoclonal antibodies

DePinho, R. A., Feldman, L. B. & Scharff, M. D., Jan 1 1986, In : Annals of internal medicine. 104, 2, p. 225-233 9 p.

Research output: Contribution to journalReview article

15 Scopus citations

The production of more useful monoclonal antibodies 2. The use of somatic-cell genetic and recombinant-DNA technology to tailor-make monoclonal antibodies

Agulla, H. L., Pollock, R. R., Spira, G. & Scharff, M. D., Dec 1986, In : Immunology today. 7, 12, p. 380-383 4 p.

Research output: Contribution to journalReview article

9 Scopus citations

The production of more useful monoclonal antibodies I. Modifications of the basic technology

French, D., Fischberg, E., Buhl, S. & Scharff, M. D., Nov 1986, In : Immunology Today. 7, 11, p. 344-346 3 p.

Research output: Contribution to journalReview article

18 Scopus citations
1984

Monoclonal antibodies: a powerful tool for selecting and analyzing mutations in antigens and antibodies.

Pollock, R. R., Teillaud, J. L. & Scharff, M. D., 1984, In : Annual review of microbiology. 38, p. 389-417 29 p.

Research output: Contribution to journalReview article

10 Scopus citations
1981

Monoclonal antibodies: a powerful new tool in biology and medicine.

Yelton, D. E. & Scharff, M. D., 1981, In : Annual review of biochemistry. 50, p. 657-680 24 p.

Research output: Contribution to journalReview article

88 Scopus citations

Monoclonal Antibodies: A New Technology for Producing Serologic Reagents

Diamond, B. A., Yelton, D. E. & Scharff, M. D., May 28 1981, In : New England Journal of Medicine. 304, 22, p. 1344-1349 6 p.

Research output: Contribution to journalReview article

65 Scopus citations

Mutational events in mouse myeloma cells.

Morrison, S. L. & Scharff, M. D., Sep 1 1981, In : Critical reviews in immunology. 3, 1, p. 1-22 22 p.

Research output: Contribution to journalReview article

33 Scopus citations
1980

Antigen binding variants of the S107 mouse myeloma cell line.

Cook, W. D., Rudikoff, S., Giusti, A. M., Zack, D. J., Kelly, T. & Scharff, M. D., Jan 1 1980, In : Progress in clinical and biological research. 42, p. 217-230 14 p.

Research output: Contribution to journalReview article

2 Scopus citations
1974

The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production.

Morrison, S. L., Baumal, R., Birshtein, B. K., Kuehl, U. M., Preud'homme, J. L., Frank, L., Jasek, T. & Scharff, M. D., Dec 1 1974, In : Society of General Physiologists series. 29, p. 233-244 12 p.

Research output: Contribution to journalReview article

4 Scopus citations
1973

The synthesis, assembly, and secretion of immunoglobulin: a biochemical and genetic approach.

Scharff, M. D., Dec 1 1973, In : Harvey lectures. 69, p. 125-142 18 p.

Research output: Contribution to journalReview article

11 Scopus citations
1970

Synthesis and assembly of immunoglobulin polypeptide chains.

Scharff, M. D. & Laskov, R., Dec 1 1970, In : Progress in Allergy. 14, p. 37-80 44 p.

Research output: Contribution to journalReview article

33 Scopus citations
1965

IMMUNOLOGIC DEFICIENCY DISORDERS ASSOCIATED WITH LYMPHOPROLIFERATIVE DISEASES.

SCHARFF, M. D. & UHR, J. W., Jan 1 1965, In : Seminars in hematology. 148, p. 47-67 21 p.

Research output: Contribution to journalReview article

7 Scopus citations