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David C. Spray, Ph.D.

  • 23113 Citations
  • 85 h-Index
1972 …2023
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  • 4 Similar Profiles
Gap Junctions Medicine & Life Sciences
Connexins Medicine & Life Sciences
Connexin 43 Medicine & Life Sciences
Astrocytes Medicine & Life Sciences
Neurons Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Genes Medicine & Life Sciences
Calcium Signaling Medicine & Life Sciences

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Grants 1977 2023

Structural, Molecular and Functional Specialization in Osteocyte Mechanosensing

Spray, D. C.

National Institutes of Health

7/11/18 → 4/30/23

Project: Research project

Osteocytes
Integrins
T-Type Calcium Channels
Purinergic P2X7 Receptors
Pharmacology

The Astrocyte Nexus: Cx43 Protein Interactions

Spray, D. C. & Scemes, E.

National Institutes of Health

8/1/15 → 7/31/20

Project: Research project

Connexin 43
Astrocytes
Connexins
Proteins
Gap Junctions

Structural, Molecular, and Functional Specialization in Osteocyte Mechanosensing

Weinbaum, S., Schaffler, M. & Spray, D. C.

National Institutes of Health

9/6/10 → 8/31/16

Project: Research project

Osteocytes
Bone and Bones
Theoretical Models
Anabolic Agents
Bioengineering

Luminescence Imaging: Molecules, Cells and Tissues

Spray, D. C.

National Institutes of Health

5/15/06 → 12/31/09

Project: Research project

Luminescence
Luminescent Proteins
Connexins
Astrocytes
Group Processes

Neuronal Gap Junctions: Cx36 Gating, Binding &Function

Spray, D. C.

National Institutes of Health

2/1/02 → 1/31/08

Project: Research project

Electrical Synapses
Connexins
Gap Junctions
Neurons
Macromolecular Substances

Publications 1972 2019

Correction: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model (Arthritis Research and Therapy (2014) 16 (508) DOI: 10.1186/s13075-014-0508-y)

Leong, D. J., Choudhury, M., Hanstein, R., Hirsh, D. M., Kim, S. J., Majeska, R. J., Schaffler, M. B., Hardin, J. A., Spray, D. C., Goldring, M. B., Cobelli, N. J. & Sun, H. H., Jan 3 2019, In : Arthritis Research and Therapy. 21, 1, 1791.

Research output: Contribution to journal › Comment/debate

Ficus
Polyphenols
Tea
Osteoarthritis
Arthritis

Gap junction mediated signaling between satellite glia and neurons in trigeminal ganglia

Spray, D. C., Iglesias, R., Shraer, N., Suadicani, S. O., Belzer, V., Hanstein, R. & Hanani, M., Jan 1 2019, In : GLIA.

Research output: Contribution to journal › Article

Trigeminal Ganglion
Gap Junctions
Neuroglia
Neurons
Sensory Ganglia

Introduction to Connexins and Pannexins in the Healthy and Diseased Nervous System with Thanks to Felikas Bukauskas

Spray, D. C., Verselis, V. K. & Bennett, M. V. L., Mar 16 2019, In : Neuroscience Letters. 695, p. 1-3 3 p.

Research output: Contribution to journal › Editorial

Connexins
Nervous System Diseases

Concentrative transport of antifolates mediated by the proton-coupled folate transporter (slc46a1); Augmentation by a hepes buffer

Zhao, R., Najmi, M., Aluri, S., Spray, D. C. & Goldman, I. D., Mar 1 2018, In : Molecular Pharmacology. 93, 3, p. 208-215 8 p.

Research output: Contribution to journal › Article

Proton-Coupled Folate Transporter
Folic Acid Antagonists
Buffers
HEPES
Tumor Microenvironment
1 Citation (Scopus)

Adrenergic Receptors on Astrocytes Modulate Gap Junctions

Scmes, E., Stout, R. F. & Spray, D. C., Jan 1 2017, Noradrenergic Signaling and Astroglia. Elsevier Inc., p. 127-144 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Connexins
Gap Junctions
Second Messenger Systems
Astrocytes
Adrenergic Receptors