Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Enzymes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Isotopes Chemical Compounds
Purine-Nucleoside Phosphorylase Medicine & Life Sciences
Kinetics Chemical Compounds
Substrates Chemical Compounds
Mycobacterium tuberculosis Medicine & Life Sciences

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Projects 1976 2023

Mutation
Anodontia
Genetic Suppression
RNA Polymerase III
Phenotype
Remission Induction
Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Immunological Synapses
Epigenomics
Chromatin
Nucleotides
Methyl-CpG-Binding Protein 2
Rett Syndrome

Research Output 1973 2019

Active-Site Glu165 Activation in Triosephosphate Isomerase and Its Deprotonation Kinetics

Deng, H., Dyer, R. B. & Callender, R., May 16 2019, In : Journal of Physical Chemistry B. 123, 19, p. 4230-4241 12 p.

Research output: Contribution to journalArticle

Triose-Phosphate Isomerase
Deprotonation
Catalytic Domain
phosphates
Phosphates

Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis

Joshi, S., Fedoseyenko, D., Mahanta, N., Ducati, R. G., Feng, M., Schramm, V. L. & Begley, T. P., Mar 14 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 363-366 4 p.

Research output: Contribution to journalArticle

Vitamin K 2
Biosynthesis
Pylorus
Anti-Bacterial Agents
Enzymes

A single discrete Rab5-binding site in phosphoinositide 3-kinase is required for tumor cell invasion

Heitz, S. D., Hamelin, D. J., Hoffmann, R. M., Greenberg, N., Salloum, G., Erami, Z., Khalil, B. D., Shymanets, A., Steidle, E. A., Gong, G. Q., Nürnberg, B., Burke, J. E., Flanagan, J. U., Bresnick, A. R. & Backer, J. M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 12, p. 4621-4633 13 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Tumors
Phosphotransferases
Binding Sites