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Xingxing Zang, Ph.D.

  • 3727 Citations
  • 31 h-Index
19992020
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T-Lymphocytes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Brugia malayi Medicine & Life Sciences
Tumor Microenvironment Medicine & Life Sciences
Ligands Medicine & Life Sciences
Mucin-3 Medicine & Life Sciences
T-cells Chemical Compounds

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Grants 2008 2020

Mechanisms and therapies of B7x and B7-H3 in T1D

Zang, X.

National Institutes of Health

9/25/15 → 8/31/20

Project: Research project

Type 1 Diabetes Mellitus
T-Lymphocytes
Therapeutics
Pancreas
Histamine H3 Receptors

The B7x pathway in the tumor microenvironment

Zang, X.

National Institutes of Health

4/1/14 → 3/31/19

Project: Research project

Tumor Microenvironment
Neoplasms
Immune Evasion
Immunotherapy
Immunity

New T Cell Coinhibitory Pathway and Type 1 Diabetes

Zang, X.

National Institutes of Health

9/30/08 → 8/31/13

Project: Research project

Type 1 Diabetes Mellitus
T-Lymphocytes
Transgenic Mice
Lymphokines
Immune System Diseases

Publications 1999 2019

Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4+T cells

Wang, S., Chen, C., Li, M., Qian, J., Sun, F., Li, Y., Yu, M., Wang, M., Zang, X., Zhu, R., Li, D. & Du, M., Jan 1 2019, In : Cell Death and Disease. 10, 1, 15.

Research output: Contribution to journal › Article

Mucin-3
Cytotoxic T-Lymphocytes
Immunoglobulins
Cytokines
T-Lymphocytes

Cell–cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models

Li, Y., Zhang, D., Xu, L., Dong, L., Zheng, J., Lin, Y., Huang, J., Zhang, Y., Tao, Y., Zang, X., Li, D. & Du, M., Jan 1 2019, In : Cellular and Molecular Immunology.

Research output: Contribution to journal › Article

Mesenchymal Stromal Cells
Macrophages
Tumor Necrosis Factor-alpha
Spontaneous Abortion
Embryonic Structures

Corrigendum: HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway (Frontiers in Cellular Neuroscience, (2019), 12, 10.3389/fncel.2018.00498)

Xu, L., Xing, Q., Huang, T., Zhou, J., Liu, T., Cui, Y., Cheng, T., Wang, Y., Zhou, X., Yang, B., Yang, G. L., Zhang, J., Zang, X., Ma, S. & Guan, F., Sep 9 2019, In : Frontiers in Cellular Neuroscience. 13, 408.

Research output: Contribution to journal › Comment/debate

Open Access
Propidium
Umbilical Cord
Neuroprotective Agents
Neurosciences
Mesenchymal Stromal Cells

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, A., Taylor, P. A., Lees, C. J., Panoskaltsis-Mortari, A., Osborn, M. J., Feser, C. J., Thangavelu, G., Melchinger, W., Refaeli, Y., Hill, G. R., Munn, D. H., Murphy, W. J., Serody, J. S., Maillard, I., Kreymborg, K., van den Brink, M., Dong, C., Huang, S., Zang, X., Allison, J. P. & 2 others, Zeiser, R. & Blazar, B. R., Jan 1 2019, In : JCI Insight. 4, 19, e127716.

Research output: Contribution to journal › Article

Graft vs Host Disease
T-Lymphocytes
Mortality
Metabolic Networks and Pathways
Oxygen Consumption

Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway

Cui, Y., Zhang, L., Wang, W., Ma, S., Liu, H., Zang, X., Zhang, Y. & Guan, F., Jan 1 2019, In : Molecular and Cellular Biochemistry.

Research output: Contribution to journal › Article

Nicotinamide N-Methyltransferase
Catenins
Wnt Signaling Pathway
Epithelial-Mesenchymal Transition
Down-Regulation