• 4064 Citations
  • 31 h-Index
19992020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Review article
2019

Immune checkpoint blockade and CAR-T cell therapy in hematologic malignancies

Wang, H., Kaur, G., Sankin, A. I., Chen, F., Guan, F. & Zang, X., Jun 11 2019, In : Journal of Hematology and Oncology. 12, 1, 59.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations

Structures of Immune Checkpoints: An Overview on the CD28-B7 Family

Liu, W. & Zang, X., Jan 1 2019, In : Advances in experimental medicine and biology. 1172, p. 63-78 16 p.

Research output: Contribution to journalReview article

1 Scopus citations

The B7x Immune Checkpoint Pathway: From Discovery to Clinical Trial

John, P., Wei, Y., Liu, W., Du, M., Guan, F. & Zang, X., Nov 2019, In : Trends in Pharmacological Sciences. 40, 11, p. 883-896 14 p.

Research output: Contribution to journalReview article

2017
25 Scopus citations

The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7-H3

Janakiram, M., Shah, U. A., Liu, W., Zhao, A., Schoenberg, M. P. & Zang, X., Mar 1 2017, In : Immunological Reviews. 276, 1, p. 26-39 14 p.

Research output: Contribution to journalReview article

56 Scopus citations
2016

Co-stimulate or Co-inhibit Regulatory T Cells, Which Side to Go?

Liu, W., Almo, S. C. & Zang, X., Nov 16 2016, In : Immunological Investigations. 45, 8, p. 813-831 19 p.

Research output: Contribution to journalReview article

15 Scopus citations

Immune checkpoint blockade in human cancer therapy: Lung cancer and hematologic malignancies

Janakiram, M., Pareek, V., Cheng, H., Narasimhulu, D. M. & Zang, X., Jun 1 2016, In : Immunotherapy. 8, 7, p. 809-819 11 p.

Research output: Contribution to journalReview article

29 Scopus citations
2015

Emerging targets in cancer immunotherapy: Beyond CTLA-4 and PD-1

Assal, A., Kaner, J., Pendurti, G. & Zang, X., Nov 2015, In : Immunotherapy. 7, 11, p. 1169-1186 18 p.

Research output: Contribution to journalReview article

27 Scopus citations

Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway

Ohaegbulam, K. C., Assal, A., Lazar-Molnar, E., Yao, Y. & Zang, X., Jan 1 2015, In : Trends in Molecular Medicine. 21, 1, p. 24-33 10 p.

Research output: Contribution to journalReview article

251 Scopus citations

New immunotherapies targeting the PD-1 pathway

Chinai, J. M., Janakiram, M., Chen, F., Chen, W., Kaplan, M. & Zang, X., Sep 12 2015, In : Trends in Pharmacological Sciences. 36, 9, p. 587-595 9 p.

Research output: Contribution to journalReview article

83 Scopus citations
2012

T cell coinhibition and immunotherapy in human breast cancer.

Janakiram, M., Abadi, Y. M., Sparano, J. A. & Zang, X., Oct 2012, In : Discovery medicine. 14, 77, p. 229-236 8 p.

Research output: Contribution to journalReview article

28 Scopus citations
2011

T cell coinhibition in prostate cancer: New immune evasion pathways and emerging therapeutics

Barach, Y. S., Lee, J. S. & Zang, X., Jan 1 2011, In : Trends in Molecular Medicine. 17, 1, p. 47-55 9 p.

Research output: Contribution to journalReview article

29 Scopus citations

T cell costimulation and coinhibition: genetics and disease.

Scandiuzzi, L., Ghosh, K. & Zang, X., Aug 2011, In : Discovery Medicine. 12, 63, p. 119-128 10 p.

Research output: Contribution to journalReview article

14 Scopus citations

The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion

Hofmeyer, K. A., Jeon, H. & Zang, X., Nov 24 2011, In : Journal of Biomedicine and Biotechnology. 2011, 451694.

Research output: Contribution to journalReview article

72 Scopus citations
2007

The B7 family and cancer therapy: Costimulation and coinhibition

Zang, X. & Allison, J. P., Sep 15 2007, In : Clinical Cancer Research. 13, 18, p. 5271-5279 9 p.

Research output: Contribution to journalReview article

247 Scopus citations
2006

To be or not to be B7

Zang, X. & Allison, J. P., Oct 2 2006, In : Journal of Clinical Investigation. 116, 10, p. 2590-2593 4 p.

Research output: Contribution to journalReview article

14 Scopus citations
2001

Serine proteinase inhibitors from nematodes and the arms race between host and pathogen

Zang, X. & Maizels, R. M., Mar 1 2001, In : Trends in Biochemical Sciences. 26, 3, p. 191-197 7 p.

Research output: Contribution to journalReview article

110 Scopus citations
1999

Vaccination against helminth parasites - The ultimate challenge for vaccinologists?

Maizels, R. M., Holland, M. J., Falcone, F. H., Zang, X. X. & Yazdanbakhsh, M., Nov 9 1999, In : Immunological Reviews. 171, p. 125-147 23 p.

Research output: Contribution to journalReview article

69 Scopus citations