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2012

Human telomeres replicate using chromosomespecific, rather than universal, replication programs

Drosopoulos, W. C., Kosiyatrakul, S. T., Yan, Z., Calderano, S. G. & Schildkraut, C. L., Apr 1 2012, In : Journal of Cell Biology. 197, 2, p. 253-266 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Identification and characterization of ToRC, a novel ISWI-containing ATP-dependent chromatin assembly complex

Emelyanov, A. V., Vershilova, E., Ignatyeva, M. A., Pokrovsky, D. K., Lu, X., Konev, A. Y. & Fyodorov, D. V., Mar 15 2012, In : Genes and Development. 26, 6, p. 603-614 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of a specific region in the E1 fusion protein involved in zinc inhibition of semliki forest virus fusion

Liu, C. Y. & Kielian, M., Apr 1 2012, In : Journal of virology. 86, 7, p. 3588-3594 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions

Patten, P. E. M., Chu, C. C., Albesiano, E., Damle, R. N., Yan, X. J., Kim, D., Zhang, L., Magli, A. R., Barrientos, J., Kolitz, J. E., Allen, S. L., Rai, K. R., Roa, S., Mongini, P. K., MacCarthy, T., Scharff, M. D. & Chiorazzi, N., Dec 6 2012, In : Blood. 120, 24, p. 4802-4811 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Multiple myeloma-related deregulation of bone marrow-derived CD34 + hematopoietic stem and progenitor cells

Bruns, I., Cadeddu, R. P., Brueckmann, I., Fröbel, J., Geyh, S., Büst, S., Fischer, J. C., Roels, F., Wilk, C. M., Schildberg, F. A., Hünerlitürkoglu, A. N., Zilkens, C., Jäger, M., Steidl, U., Zohren, F., Fenk, R., Kobbe, G., Brors, B., Czibere, A., Schroeder, T. & 2 others, Trumpp, A. & Haas, R., Sep 27 2012, In : Blood. 120, 13, p. 2620-2630 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
24 Scopus citations

Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS

Barreyro, L., Will, B., Bartholdy, B., Zhou, L., Todorova, T. I., Stanley, R. F., Ben-Neriah, S., Montagna, C., Parekh, S., Pellagatti, A., Boultwood, J., Paietta, E., Ketterling, R. P., Cripe, L., Fernandez, H. F., Greenberg, P. L., Tallman, M. S., Steidl, C., Mitsiades, C. S., Verma, A. & 1 others, Steidl, U., Aug 9 2012, In : Blood. 120, 6, p. 1290-1298 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus

Frezza, D., Tolusso, B., Giambra, V., Gremese, E., Marchini, M., Nowik, M., Serone, E., D'Addabbo, P., Mattioli, C., Canestri, S., Petricca, L., D'Antona, G., Birshtein, B. K., Scorza, R. & Ferraccioli, G., Aug 1 2012, In : Annals of the Rheumatic Diseases. 71, 8, p. 1309-1315 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment

Demczuk, A., Gauthier, M. G., Veras, I., Kosiyatrakul, S., Schildkraut, C. L., Busslinger, M., Bechhoefer, J. & Norio, P., Jul 1 2012, In : PLoS biology. 10, 7, 1 p., e1001360.

Research output: Contribution to journalArticle

30 Scopus citations

Role of a DNA damage checkpoint pathway in ionizing radiation-induced glioblastoma cell migration and invasion

Vanan, I., Dong, Z., Tosti, E., Warshaw, G., Symons, M. & Ruggieri, R., Oct 1 2012, In : Cellular and Molecular Neurobiology. 32, 7, p. 1199-1208 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

S-layer proteins of Lactobacillus acidophilus inhibits JUNV infection

Martínez, M. G., Prado Acosta, M., Candurra, N. A. & Ruzal, S. M., Jun 15 2012, In : Biochemical and Biophysical Research Communications. 422, 4, p. 590-595 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

SLiCE: A novel bacterial cell extract-based DNA cloning method

Zhang, Y., Werling, U. & Edelmann, W., Apr 1 2012, In : Nucleic Acids Research. 40, 8, p. e55

Research output: Contribution to journalArticle

250 Scopus citations

Slug and Sox9 cooperatively determine the mammary stem cell state

Guo, W., Keckesova, Z., Donaher, J. L., Shibue, T., Tischler, V., Reinhardt, F., Itzkovitz, S., Noske, A., Zürrer-Härdi, U., Bell, G., Tam, W. L., Mani, S. A., Van Oudenaarden, A. & Weinberg, R. A., Mar 2 2012, In : Cell. 148, 5, p. 1015-1028 14 p.

Research output: Contribution to journalArticle

548 Scopus citations

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

Will, B., Zhou, L., Vogler, T. O., Ben-Neriah, S., Schinke, C., Tamari, R., Yu, Y., Bhagat, T. D., Bhattacharyya, S., Barreyro, L., Heuck, C., Mo, Y., Parekh, S., McMahon, C., Pellagatti, A., Boultwood, J., Montagna, C., Silverman, L., Maciejewski, J., Greally, J. M. & 5 others, Ye, B. H., List, A. F., Steidl, C., Steidl, U. & Verma, A., Sep 6 2012, In : Blood. 120, 10, p. 2076-2086 11 p.

Research output: Contribution to journalArticle

118 Scopus citations
17 Scopus citations

Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets

Alfaro, J. F., Gong, C. X., Monroe, M. E., Aldrich, J. T., Clauss, T. R. W., Purvine, S. O., Wang, Z., Camp, D. G., Shabanowitz, J., Stanley, P., Hart, G. W., Hunt, D. F., Yang, F. & Smith, R. D., May 8 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7280-7285 6 p.

Research output: Contribution to journalArticle

171 Scopus citations

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination

Chahwan, R., van Oers, J. M. M., Avdievich, E., Zhao, C., Edelmann, W., Scharff, M. D. & Roa, S. R., Apr 9 2012, In : Journal of Experimental Medicine. 209, 4, p. 671-678 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

The bisecting GlcNAc in cell growth control and tumor progression

Miwa, H. E., Song, Y., Alvarez, R., Cummings, R. D. & Stanley, P., Dec 1 2012, In : Glycoconjugate Journal. 29, 8-9, p. 609-618 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel

Sroubek, J., Krishnan, Y., Chinai, J., Buhl, S., Scharff, M. D. & McDonald, T. V., Jan 31 2012, In : Journal of Immunological Methods. 375, 1-2, p. 215-222 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Zinc-finger nuclease-mediated correction of α-thalassemia in iPS cells

Chang, C. J. & Bouhassira, E. E., Nov 8 2012, In : Blood. 120, 19, p. 3906-3914 9 p.

Research output: Contribution to journalArticle

69 Scopus citations
2011

Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q

Zhou, L., Opalinska, J., Sohal, D., Yu, Y., Mo, Y., Bhagat, T., Abdel-Wahab, O., Fazzari, M., Figueroa, M., Alencar, C., Zhang, J., Kambhampati, S., Parmar, S., Nischal, S., Hueck, C., Suzuki, M., Freidman, E., Pellagatti, A., Boultwood, J., Steidl, U. & 10 others, Sauthararajah, Y., Yajnik, V., Mcmahon, C., Gore, S. D., Platanias, L. C., Levine, R., Melnick, A., Wickrema, A., Greally, J. M. & Vermaa, A., Jul 15 2011, In : Journal of Biological Chemistry. 286, 28, p. 25211-25223 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function

Wei, Q. & Condie, B. G., Nov 7 2011, In : PloS one. 6, 11, e26795.

Research output: Contribution to journalArticle

12 Scopus citations

A large gene network in immature Erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1

Wontakal, S. N., Guo, X., Will, B., Shi, M., Raha, D., Mahajan, M. C., Weissman, S., Snyder, M., Steidl, U., Zheng, D. & Skoultchi, A. I., Jun 1 2011, In : PLoS genetics. 7, 6, e1001392.

Research output: Contribution to journalArticle

29 Scopus citations

Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model

Mcilhatton, M. A., Tyler, J., Kerepesi, L. A., Bocker-Edmonston, T., Kucherlapati, M. H., Edelmann, W., Kucherlapati, R., Kopelovich, L. & Fishel, R., May 1 2011, In : Cancer Prevention Research. 4, 5, p. 684-693 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition

Duy, C., Hurtz, C., Shojaee, S., Cerchietti, L., Geng, H., Swaminathan, S., Klemm, L., Kweon, S. M., Nahar, R., Braig, M., Park, E., Kim, Y. M., Hofmann, W. K., Herzog, S., Jumaa, H., Koeffler, H. P., Yu, J. J., Heisterkamp, N., Graeber, T. G., Wu, H. & 3 others, Ye, B. H., Melnick, A. & Müschen, M., May 19 2011, In : Nature. 473, 7347, p. 384-391 8 p.

Research output: Contribution to journalArticle

134 Scopus citations

BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia

Hurtz, C., Hatzi, K., Cerchietti, L., Braig, M., Park, E., Kim, Y. M., Herzog, S., Ramezani-Rad, P., Jumaa, H., Müller, M. C., Hofmann, W. K., Hochhaus, A., Ye, B. H., Agarwal, A., Druker, B. J., Shah, N. P., Melnick, A. M. & Müschen, M., Oct 24 2011, In : Journal of Experimental Medicine. 208, 11, p. 2163-2174 12 p.

Research output: Contribution to journalArticle

123 Scopus citations

CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells

Degner, S. C., Verma-Gaur, J., Wong, T. P., Bossen, C., Iverson, G. M., Torkamani, A., Vettermann, C., Lin, Y. C., Ju, Z., Schulz, D., Murre, C. S., Birshtein, B. K., Schork, N. J., Schlissel, M. S., Riblet, R., Murre, C. & Feeney, A. J., Jun 7 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 23, p. 9566-9571 6 p.

Research output: Contribution to journalArticle

144 Scopus citations

Dynamic changes in binding of immunoglobulin heavy chain 3′ regulatory region to protein factors during class switching

Chatterjee, S., Ju, Z., Hassan, R., Volpi, S. A., Emelyanov, A. V. & Birshtein, B. K., Aug 19 2011, In : Journal of Biological Chemistry. 286, 33, p. 29303-29312 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Fluorescence spectroscopy as a probe of the effect of phosphorylation at serine 40 of tyrosine hydroxylase on the conformation of its regulatory domain

Wang, S., Lasagna, M., Daubner, S. C., Reinhart, G. D. & Fitzpatrick, P. F., Mar 29 2011, In : Biochemistry. 50, 12, p. 2364-2370 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock

Varshney, A. K., Wang, X., Cook, E., Dutta, K., Scharff, M. D., Goger, M. J. & Fries, B. C., Mar 18 2011, In : Journal of Biological Chemistry. 286, 11, p. 9737-9747 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

GenPlay, a multipurpose genome analyzer and browser

Lajugie, J. & Bouhassira, E. E., Jul 1 2011, In : Bioinformatics. 27, 14, p. 1889-1893 5 p., btr309.

Research output: Contribution to journalArticle

17 Scopus citations

Golgi glycosylation

Stanley, P., Apr 1 2011, In : Cold Spring Harbor Perspectives in Biology. 3, 4, p. 1-13 13 p.

Research output: Contribution to journalArticle

147 Scopus citations

Homologous elements hs3a and hs3b in the 3′ regulatory region of the murine immunoglobulin heavy chain (Igh) locus are both dispensable for class-switch recombination

Yan, Y., Pieretti, J., Ju, Z., Wei, S., Christin, J. R., Bah, F., Birshtein, B. K. & Eckhardt, L. A., Aug 5 2011, In : Journal of Biological Chemistry. 286, 31, p. 27123-27131 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Interaction between the immunoglobulin heavy chain 3' regulatory region and the IgH transcription unit during B cell differentiation

Ju, Z., Chatterjee, S. & Birshtein, B. K., Oct 1 2011, In : Molecular Immunology. 49, 1-2, p. 297-303 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Intraclonal complexity in chronic lymphocytic leukemia: Fractions enriched in recently born/divided and older/quiescent cells

Calissano, C., Damle, R. N., Marsilio, S., Yan, X. J., Yancopoulos, S., Hayes, G., Emson, C., Murphy, E. J., Hellerstein, M. K., Sison, C., Kaufman, M. S., Kolitz, J. E., Allen, S. L., Rai, K. R., Ivanovic, I., Dozmorov, I. M., Roa, S., Scharff, M. D., Li, W. & Chiorazzi, N., Nov 1 2011, In : Molecular Medicine. 17, 11, p. 1374-1382 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

Steidl, C., Shah, S. P., Woolcock, B. W., Rui, L., Kawahara, M., Farinha, P., Johnson, N. A., Zhao, Y., Telenius, A., Neriah, S. B., McPherson, A., Meissner, B., Okoye, U. C., Diepstra, A., Van Den Berg, A., Sun, M., Leung, G., Jones, S. J., Connors, J. M., Huntsman, D. G. & 7 others, Savage, K. J., Rimsza, L. M., Horsman, D. E., Staudt, L. M., Steidl, U., Marra, M. A. & Gascoyne, R. D., Mar 17 2011, In : Nature. 471, 7338, p. 377-383 7 p.

Research output: Contribution to journalArticle

374 Scopus citations

Mismatch-mediated error prone repair at the immunoglobulin genes

Chahwan, R., Edelmann, W., Scharff, M. D. & Roa, S., Dec 1 2011, In : Biomedicine and Pharmacotherapy. 65, 8, p. 529-536 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC

Nahar, R., Ramezani-Rad, P., Mossner, M., Duy, C., Cerchietti, L., Geng, H., Dovat, S., Jumaa, H., Ye, B. H., Melnick, A. & Müschen, M., Oct 13 2011, In : Blood. 118, 15, p. 4174-4178 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Premature ovarian failure in mice with oocytes lacking core 1-derived O-glycans and complex N-glycans

Williams, S. A. & Stanley, P., Mar 2011, In : Endocrinology. 152, 3, p. 1057-1066 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Production of embryonic and fetal-like red blood cells from human induced pluripotent stem cells

Chang, C. J., Mitra, K., Koya, M., Velho, M., Desprat, R., Lenz, J. & Bouhassira, E. E., Oct 13 2011, In : PloS one. 6, 10, e25761.

Research output: Contribution to journalArticle

48 Scopus citations

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

Yao, D., Huang, Y., Huang, X., Wang, W., Yan, Q., Wei, L., Xin, W., Gerson, S., Stanley, P., Lowe, J. B. & Zhou, L., May 26 2011, In : Blood. 117, 21, p. 5652-5662 11 p.

Research output: Contribution to journalArticle

64 Scopus citations

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in ramos cells

Baughn, L. B., Kalis, S. L., MacCarthy, T., Wei, L., Fan, M., Bergman, A. & Scharff, M. D., 2011, In : mBio. 2, 5, e00186-11.

Research output: Contribution to journalArticle

6 Scopus citations

Reduced SMAD7 leads to overactivation of TGF-β signaling in MDS that can be reversed by a specific inhibitor of TGF-β receptor I kinase

Zhou, L., McMahon, C., Bhagat, T., Alencar, C., Yu, Y., Fazzari, M., Sohal, D., Heuck, C., Gundabolu, K., Ng, C., Mo, Y., Shen, W., Wickrema, A., Kong, G., Friedman, E., Sokol, L., Mantzaris, G., Pellagatti, A., Boultwood, J., Platanias, L. C. & 7 others, Steidl, U., Yan, L., Yingling, J. M., Lahn, M. M., List, A., Bitzer, M. & Verma, A., Feb 1 2011, In : Cancer research. 71, 3, p. 955-963 9 p.

Research output: Contribution to journalArticle

82 Scopus citations

Reprogramming of embryonic human fibroblasts into fetal hematopoietic progenitors by fusion with human fetal liver cd34+ cells

Sandler, V. M., Lailler, N. & Bouhassira, E. E., 2011, In : PloS one. 6, 4, e18265.

Research output: Contribution to journalArticle

9 Scopus citations

Single molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication

Verma, S. C., Lu, J., Cai, Q., Kosiyatrakul, S., McDowell, M. E., Schildkraut, C. L. & Robertson, E. S., Nov 1 2011, In : PLoS pathogens. 7, 11, e1002365.

Research output: Contribution to journalArticle

21 Scopus citations

Single-molecule mRNA decay measurements reveal promoter-regulated mRNA stability in yeast

Trcek, T., Larson, D. R., Moldón, A., Query, C. C. & Singer, R. H., Dec 23 2011, In : Cell. 147, 7, p. 1484-1497 14 p.

Research output: Contribution to journalArticle

162 Scopus citations

Systematic targeted integration to study Albumin gene control elements

Bhattacharyya, S., Tian, J., Bouhassira, E. E. & Locker, J., 2011, In : PloS one. 6, 8, e23234.

Research output: Contribution to journalArticle

1 Scopus citations

The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization

Morettini, S., Tribus, M., Zeilner, A., Sebald, J., Campo-Fernandez, B., Scheran, G., Wörle, H., Podhraski, V., Fyodorov, D. V. & Lusser, A., Apr 2011, In : Nucleic acids research. 39, 8, p. 3103-3115 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

The domain I-domain III linker plays an important role in the fusogenic conformational change of the alphavirus membrane fusion protein

Zheng, Y., Martín, C. S. S., Qin, Z. L. & Kielian, M., Jul 2011, In : Journal of virology. 85, 13, p. 6334-6342 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin

Ott, E., Norio, P., Ritzi, M., Schildkraut, C. & Schepers, A., May 23 2011, In : PloS one. 6, 5, e18609.

Research output: Contribution to journalArticle

13 Scopus citations