Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Semliki forest virus Medicine & Life Sciences
Cells Chemical Compounds
Proteins Medicine & Life Sciences
DNA Mismatch Repair Medicine & Life Sciences
Cricetulus Medicine & Life Sciences
Polysaccharides Medicine & Life Sciences

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Projects 1975 2023

Mutation
Antibodies
Genes
Databases
Immunoglobulin Variable Region
Hematopoietic Stem Cells
Cell Division
Transplantation
Bone Marrow
Stem Cell Niche
Stem Cells
Small Interfering RNA
Leukemia
Recurrence
Critical Pathways

Research Output 1965 2018

A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche

Guarnerio, J., Mendez, L. M., Asada, N., Menon, A. V., Fung, J., Berry, K., Frenette, P. S., Ito, K. & Pandolfi, P. P. Dec 1 2018 In : Nature Communications. 9, 1, 66

Research output: Contribution to journalArticle

cells and cell components
disease treatment
leukemias
maintenance
niche

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A. , Ben Neriah, D. , Senecal, A. , Benard, L. , Thiruthuvanathan, V. , Yatsenko, T. , Narayanagari, S. R. , Wheat, J. C. , Todorova, T. I. , Mitchell, K. , Kenworthy, C. , Guerlavais, V. , Annis, D. A. , Bartholdy, B. , Will, B. , Anampa, J. D. , Mantzaris, I. , Aivado, M. , Singer, R. H. , Coleman, R. A. & 2 others Verma, A. & Steidl, U. Apr 11 2018 In : Science Translational Medicine. 10, 436, aao3003

Research output: Contribution to journalArticle

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints

Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD

Escudero, S., Zaganjor, E., Lee, S., Mill, C. P., Morgan, A. M., Crawford, E. B., Chen, J., Wales, T. E., Mourtada, R., Luccarelli, J., Bird, G. H., Steidl, U., Engen, J. R., Haigis, M. C., Opferman, J. T. & Walensky, L. D. Mar 1 2018 In : Molecular Cell. 69, 5, p. 802-819.e1

Research output: Contribution to journalArticle

Long-Chain Acyl-CoA Dehydrogenase
Mitochondria
Fatty Acids
Apoptosis
Lipid Metabolism