Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Semliki forest virus Medicine & Life Sciences
Cells Chemical Compounds
Proteins Medicine & Life Sciences
DNA Mismatch Repair Medicine & Life Sciences
Cricetulus Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences

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Projects 1975 2023

Therapeutic targeting of MDS stem cells

Verma, A. K. & Steidl, U. G.

National Institutes of Health

8/20/186/30/22

Project: Research projectResearch Project

Interleukin-8
Stem Cells
Therapeutics
Heterografts
Disease Progression
Histones
Drosophila
Chromatin
Chromosomes
Post Translational Protein Processing
Colon
Carcinogenesis
Hereditary Nonpolyposis Colorectal Neoplasms
Stem Cells
Penetrance

Research Output 1965 2018

2 Citations

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

Maryanovich, M., Zahalka, A. H., Pierce, H., Pinho, S., Nakahara, F., Asada, N., Wei, Q., Wang, X., Ciero, P., Xu, J., Leftin, A. & Frenette, P. S., May 7 2018, (Accepted/In press) In : Nature Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Nerve Degeneration
Hematopoietic Stem Cells
Stem cells
Adrenergic Agents
1 Citations

A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche

Guarnerio, J., Mendez, L. M., Asada, N., Menon, A. V., Fung, J., Berry, K., Frenette, P. S., Ito, K. & Pandolfi, P. P., Dec 1 2018, In : Nature Communications. 9, 1, 66.

Research output: Contribution to journalArticle

leukemias
maintenance
niche
Leukemia
Maintenance
3 Citations

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S. R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B., Will, B., Anampa, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 othersVerma, A. & Steidl, U., Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.

Research output: Contribution to journalArticle

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints