Regulation of phosphatidylinositol 3′-kinase by tyrosyl phosphoproteins: Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit

Medicine & Life Sciences

• Insulin Receptor Substrate Proteins 100%
• src Homology Domains 93%
• Phosphoproteins 90%
• Phosphatidylinositol 3-Kinase 78%
• Phosphopeptides 51%
• Peptides 12%
• Mutation 10%
• Insulin 6%
• In Vitro Techniques 4%
• Proteins 3%

Chemical Compounds

• Phosphatidylinositol 92%
• Insulin Derivative 78%
• Mutation 16%
• Peptide 11%
• Protein 3%