Isofraxidin, a coumarin component improves high-fat diet induced hepatic lipid homeostasis disorder and macrophage inflammation in mice

Agriculture & Biology

• coumarin 61%
• high fat diet 54%
• inflammation 46%
• macrophages 45%
• homeostasis 43%
• liver 29%
• mice 29%
• lipids 27%
• lipid metabolism disorders 18%
• lipotoxicity 17%
• triacylglycerols 16%
• Eleutherococcus senticosus 15%
• Apium graveolens 14%
• Kupffer cells 14%
• fatty liver 12%
• lipogenesis 12%
• interleukin-6 11%
• hepatoma 11%
• anti-inflammatory activity 10%
• functional foods 10%
• lipid metabolism 10%
• protective effect 9%
• cells 9%
• cytokines 9%
• oleic acid 9%
• phosphorylation 8%
• therapeutics 7%
• body weight 6%
• metabolism 5%
• tissues 4%
• methodology 2%

Medicine & Life Sciences

• isofraxidin 100%
• coumarin 68%
• High Fat Diet 51%
• Homeostasis 37%
• Macrophages 35%
• Lipids 33%
• Inflammation 29%
• Liver 26%
• Apium 9%
• Eleutherococcus 9%
• Triglycerides 9%
• Lipid Metabolism Disorders 8%
• Functional Food 6%
• Lipogenesis 6%
• Metabolic Activation 6%
• Kupffer Cells 6%
• Oleic Acid 6%
• Non-alcoholic Fatty Liver Disease 6%
• Hep G2 Cells 6%
• Lipid Metabolism 5%
• Hepatocellular Carcinoma 4%
• Interleukin-6 4%
• Anti-Inflammatory Agents 4%
• Body Weight 4%
• Down-Regulation 3%
• Phosphorylation 3%
• Therapeutics 3%
• Weights and Measures 3%
• Cytokines 3%
• Wounds and Injuries 2%
• In Vitro Techniques 2%