• 13420 Citations
  • 63 h-Index
1968 …2022
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Fingerprint Dive into the research topics where Vern L. Schramm is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Purine-Nucleoside Phosphorylase Medicine & Life Sciences
Isotopes Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Kinetics Chemical Compounds
AMP nucleosidase Medicine & Life Sciences
N-Glycosyl Hydrolases Chemical Compounds
Catalytic Domain Medicine & Life Sciences
Substrates Chemical Compounds

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Grants 1979 2022

African Trypanosomiasis
Trypanosoma brucei brucei
Chagas Disease
Plasmodium falciparum
Malaria
Isotopes
Enzymes
Purine-Nucleoside Phosphorylase
Inosine
Hydrolases
Nucleosides
Oligonucleotides
Nucleotides
Research
Synthetic Biology
Triple Negative Breast Neoplasms
Neoplasms
Breast Neoplasms
Growth
Therapeutics
Ligases
DNA Methylation
Neoplasms
Growth
Head and Neck Neoplasms

Publications 1968 2019

  • 13420 Citations
  • 63 h-Index
  • 349 Article
  • 6 Chapter
  • 3 Review article
  • 1 Comment/debate

Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis

Joshi, S., Fedoseyenko, D., Mahanta, N., Ducati, R. G., Feng, M., Schramm, V. L. & Begley, T. P., Mar 14 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 363-366 4 p.

Research output: Contribution to journalArticle

Vitamin K 2
Biosynthesis
Pylorus
Anti-Bacterial Agents
Enzymes

Enhanced antibiotic discovery by PROSPECTing

Schramm, V. L. & Meek, T. D., Aug 20 2019, In : Biochemistry. 58, 33, p. 3475-3476 2 p.

Research output: Contribution to journalComment/debate

Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase

Harijan, R. K., Hoff, O., Ducati, R. G., Firestone, R. S., Hirsch, B. M., Evans, G. B., Schramm, V. L. & Tyler, P. C., Apr 11 2019, In : Journal of Medicinal Chemistry. 62, 7, p. 3286-3296 11 p.

Research output: Contribution to journalArticle

adenosylhomocysteine nucleosidase
Helicobacter pylori
Vitamin K 2
S-Adenosylmethionine
Catalytic Domain
1 Citation (Scopus)

Enzymatic Transition States and Drug Design

Schramm, V. L., Jan 1 2018, (Accepted/In press) In : Chemical Reviews.

Research output: Contribution to journalArticle

Computational chemistry
Quantum chemistry
Isotopes
Pharmaceutical Preparations
Kinetics
4 Citations (Scopus)

Genetic resistance to purine nucleoside phosphorylase inhibition in plasmodium falciparum

Ducati, R. G., Namanja-Magliano, H. A., Harijan, R. K., Eduardo Fajardo, J., Fiser, A., Daily, J. P. & Schramm, V. L., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 2114-2119 6 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Plasmodium falciparum
Antimalarials
Gene Amplification
Starvation