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Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Almo, S. C., Goel, S., Goldman, I. D., Chu, E., Goldman, I. D., Scharff, M. D., Eagle, H., Seither, R., Bresnick, A. R., Condeelis, J. S., Herbst, L. H., Xue, X. N., Stein, D. T., Blanchard, J. S., Rohan, T. E., Porcelli, S. A., Edelmann, W., Morrow, B. E., Beck, A. P., Montagna, C., Steidl, U. G., Schramm, V. L., Strickler, H., Augenlicht, L. H., Rapkin, B. D. & Sparano, J. A.
12/31/89 → 6/30/22
Project: Research project
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Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins
National Institute of Allergy and Infectious Diseases
4/1/21 → 3/31/22
Project: Research project
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PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE
Schramm, V. L. & Schramm, V. L.
9/25/17 → 8/31/21
Project: Research project
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PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE
Meek, T., Schramm, V. L. & Tyler, P.
National Institute of Allergy and Infectious Diseases
9/25/17 → 8/31/19
Project: Research project
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2015 Nucleosides, Nucleotides & Oligonucleotides Gordon Research Conference and Seminar
National Institute of Allergy and Infectious Diseases
5/18/15 → 9/30/15
Project: Research project
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Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1
Lamiable-Oulaidi, F., Harijan, R. K., Shaffer, K. J., Crump, D. R., Sun, Y., Du, Q., Gulab, S. A., Khan, A. A., Luxenburger, A., Woolhouse, A. D., Sidoli, S., Tyler, P. C. & Schramm, V. L., Apr 14 2022, In: Journal of Medicinal Chemistry. 65, 7, p. 5462-5494 33 p.Research output: Contribution to journal › Article › peer-review
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Aminofutalosine Deaminase in the Menaquinone Pathway ofHelicobacter pylori
Feng, M., Harijan, R. K., Harris, L. D., Tyler, P. C., Fröhlich, R. F. G., Brown, M. & Schramm, V. L., Jun 22 2021, In: Biochemistry. 60, 24, p. 1933-1946 14 p.Research output: Contribution to journal › Article › peer-review
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A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival
Minnow, Y. V. T., Harijan, R. K. & Schramm, V. L., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100342.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues
Paparella, A. S., Aboulache, B. L., Harijan, R. K., Potts, K. S., Tyler, P. C. & Schramm, V. L., Dec 2021, In: Nature communications. 12, 1, 6285.Research output: Contribution to journal › Article › peer-review
Open Access -
Inverse heavy enzyme isotope effects in methylthioadenosine nucleosidases
Brown, M., Zoi, I., Antoniou, D., Namanja-Magliano, H. A., Schwartz, S. D. & Schramm, V. L., Oct 5 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 40, e2109118118.Research output: Contribution to journal › Article › peer-review
1 Scopus citations