Projects per year
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Collaborations and top research areas from the last five years
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Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins
National Institute of Allergy and Infectious Diseases
4/1/21 → 3/31/24
Project: Research project
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Transition State Analysis of Enzymatic Reactions
Schramm, V. L. & Schramm, V. V. L.
National Institute of General Medical Sciences
8/1/89 → 7/31/24
Project: Research project
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Cancer Center Support Grant
Almo, S. C., Hogue-Angeletti, R., Augenlicht, L. H., Condeelis, J. S., Desai, K., Edelmann, W., Goldman, I. D., Greally, J. M., Herbst, L. H., Keller, S. M., Kim, M. Y., Mahmood, R., Montagna, C., Morrow, B. E., Pollard, J. W., Porcelli, S. A., Rohan, T. E., Scharff, M. D., Seither, R., Skoultchi, A. I., Sparano, J. A., Stanley, P. M., Chu, E. E., Bresnick, A. R., Skoultchi, A. I., Adedimeji, A. A., Beck, A. P., Blanchard, J. S., Halmos, B., Diamond, B. B., Rapkin, B. D., Chu, E., Stein, D. T., Gaertner, D. D. J., Chu, E., Ho, G. Y. F., Goel, S., Hosgood, H. D. H., Strickler, H., Pollard, J. J. W., Condeelis, J. S., Dutcher, J. P., Backer, J. M., Sparano, J., Aguirre-ghiso, J. J. A., Gritsman, K., Herbst, L. H., Augenlicht, L. H., Cannizzaro, L. A., Hackett, L. L. E., Scharff, M. D., Brenowitz, M. D., Kim, M., Ohri, N., Stanley, P., Gupta, R. R. K., Seither, R. R. L., Depinho, R. R. A., Kucherlapati, R. R. S., Schramm, V. L., Keller, S. M., Porcelli, S. A., Rohan, T. E., Steidl, U. U. G., Xue, X., Alderman, M. H., Atkinson, P. H., Bases, R. E., Birshstein, B. K., Bloom, B. R., Blumenfeld, O. O., Brenowitz, M. D., Brewer, F. C., Buhl, S., Chance, M. R., Chase, J. W., Childs, G. J., Depinho, R., Depinho, R. A., Duran-reynals, M. L., Dutcher, J. P., Eagle, H., Fant, J., Gaertner, D. J., Grills, G., Gupta, R. K., Ho, G. Y., Band Horwitz, S., Horwitz, M. S., Hurwitz, J., Kadish, A. S., Klinger, H. P., Krauter, K. S., Kucherlapati, R. S., Levine, W. G., Lilly, F., Maio, J. J., Maitra, U., Makman, M. H., Marians, K. J., Nathenson, S. G., Orr, G. A., Peisach, J., Pickering, K., Rajan, T. V., Reid, L. M., Rubin, C. S., Russel, R., Satir, B. H., Schildkraut, C. L., Schulman, L. H., Serrano, L. J., Shapiro, L., Shin, S., Wadler, S. H., Warner, J. R., West, M. & Wiernik, P. H.
6/1/85 → 6/30/24
Project: Research project
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PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE
Schramm, V. L. & Schramm, V. L.
9/25/17 → 8/31/21
Project: Research project
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Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition
Bedard, G. T., Gilaj, N., Peregrina, K., Brew, I., Tosti, E., Shaffer, K., Tyler, P. C., Edelmann, W., Augenlicht, L. H. & Schramm, V. L., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105492.Research output: Contribution to journal › Article › peer-review
Open Access -
Isofagomine Inhibits Multiple TcdB Variants and Protects Mice from Clostridioides difficile-Induced Mortality
Paparella, A. S., Brew, I., Hong, H. A., Ferriera, W., Cutting, S., Lamiable-Oulaidi, F., Popadynec, M., Tyler, P. C. & Schramm, V. L., Mar 8 2024, In: ACS Infectious Diseases. 10, 3, p. 928-937 10 p.Research output: Contribution to journal › Article › peer-review
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An enzyme-coupled microplate assay for activity and inhibition of hmdUMP hydrolysis by DNPH1
Wagner, A. G., Eskandari, R. & Schramm, V. L., Jul 1 2023, In: Analytical Biochemistry. 672, 115171.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Cell-Effective Transition-State Analogue of Phenylethanolamine N-Methyltransferase
Mahmoodi, N., Minnow, Y. V. T., Harijan, R. K., Bedard, G. T. & Schramm, V. L., Aug 1 2023, In: Biochemistry. 62, 15, p. 2257-2268 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis
Brown, M. & Schramm, V. L., Oct 17 2023, In: Biochemistry. 62, 20, p. 2928-2933 6 p.Research output: Contribution to journal › Article › peer-review
Open Access