• 2078 Citations
  • 25 h-Index
1980 …2023
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  • 2 Similar Profiles
Sulfate Adenylyltransferase Medicine & Life Sciences
Sulfotransferases Medicine & Life Sciences
Sulfates Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences
Phosphoadenosine Phosphosulfate Medicine & Life Sciences
Enzymes Medicine & Life Sciences
GTP Phosphohydrolases Chemical Compounds
Adenosine Phosphosulfate Medicine & Life Sciences

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Grants 1990 2023

Sulfotransferases
Libraries
Neurotransmitter Agents
Protein Isoforms
Ligands
Allosteric Regulation
Sulfotransferases
Protein Isoforms
Small Molecule Libraries
Dopamine
Sulfotransferases
Substrates
Metabolism
Celecoxib
Enzymes
Mevalonic Acid
mevalonate kinase
Streptococcus pneumoniae
Streptococcus
Anti-Bacterial Agents
Estrogens
Conjugated (USP) Estrogens
Sulfotransferases
Estrogen Replacement Therapy
Endometrium

Publications 1980 2019

  • 2078 Citations
  • 25 h-Index
  • 82 Article

Allosteres to regulate neurotransmitter sulfonation

Darrah, K., Wang, T., Cook, I. T., Cacace, M., Deiters, A. & Leyh, T. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 7, p. 2293-2301 9 p.

Research output: Contribution to journalArticle

Sulfotransferases
Sulfonation
Neurotransmitter Agents
Free energy
Allosteric Site

Isoform-specific therapeutic control of sulfonation in humans

Cook, I. T., Wang, T. & Leyh, T. S., Jan 1 2019, In : Biochemical Pharmacology. 159, p. 25-31 7 p.

Research output: Contribution to journalArticle

Sulfonation
Acetaminophen
Sulfotransferases
Mefenamic Acid
Protein Isoforms
4 Citations (Scopus)

STRENDA DB: Enabling the validation and sharing of enzyme kinetics data

Swainston, N., Baici, A., Bakker, B. M., Cornish-Bowden, A., Fitzpatrick, P. F., Halling, P., Leyh, T. S., O'Donovan, C., Raushel, F. M., Reschel, U., Rohwer, J. M., Schnell, S., Schomburg, D., Tipton, K. F., Tsai, M. D., Westerhoff, H. V., Wittig, U., Wohlgemuth, R. & Kettner, C., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

User-Computer Interface
Protein Databases
Information Dissemination
Enzyme Assays
Fungi
4 Citations (Scopus)
Neurotransmitter Agents
Sulfotransferases
Catechin
Allosteric Site
Binding Sites
2 Citations (Scopus)

The NSAID allosteric site of human cytosolic sulfotransferases

Wang, T., Cook, I. T. & Leyh, T. S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 49, p. 20305-20312 8 p.

Research output: Contribution to journalArticle

Allosteric Site
Sulfotransferases
Anti-Inflammatory Agents
Pharmaceutical Preparations
Mefenamic Acid