• 2014 Citations
  • 25 h-Index
1980 …2023
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  • 2 Similar Profiles
Sulfate Adenylyltransferase Medicine & Life Sciences
Sulfotransferases Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences
Sulfates Medicine & Life Sciences
Phosphoadenosine Phosphosulfate Medicine & Life Sciences
Enzymes Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
Adenosine Phosphosulfate Medicine & Life Sciences

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Grants 1990 2023

The Study of Human Sulfuryl-Transfer Biology

Leyh, T. S.

National Institutes of Health

9/8/188/31/23

Project: Research projectOutstanding Investigator Award

Sulfotransferases
Libraries
Neurotransmitter Agents
Protein Isoforms
Ligands
Allosteric Regulation
Sulfotransferases
Protein Isoforms
Small Molecule Libraries
Dopamine
Sulfotransferases
Substrates
Metabolism
Celecoxib
Enzymes

The Mevalonate Pathway in Streptococcus

Leyh, T. S.

National Institutes of Health

4/1/063/31/12

Project: Research projectResearch Project

Mevalonic Acid
mevalonate kinase
Streptococcus pneumoniae
Streptococcus
Anti-Bacterial Agents

SULFURYL-TRANSFER--THE HUMAN ESTROGEN SULFOTRANSFERASE

Leyh, T. S.

National Institutes of Health

2/1/001/31/05

Project: Research projectResearch Project

Estrogens
Conjugated (USP) Estrogens
Sulfotransferases
Estrogen Replacement Therapy
Endometrium

Publications 1980 2019

  • 2014 Citations
  • 25 h-Index
  • 81 Article

Isoform-specific therapeutic control of sulfonation in humans

Cook, I. T., Wang, T. & Leyh, T. S., Jan 1 2019, In : Biochemical Pharmacology. 159, p. 25-31 7 p.

Research output: Contribution to journalArticle

Sulfonation
Acetaminophen
Sulfotransferases
Mefenamic Acid
Protein Isoforms
2 Citations

STRENDA DB: Enabling the validation and sharing of enzyme kinetics data

Swainston, N., Baici, A., Bakker, B. M., Cornish-Bowden, A., Fitzpatrick, P. F., Halling, P., Leyh, T. S., O'Donovan, C., Raushel, F. M., Reschel, U., Rohwer, J. M., Schnell, S., Schomburg, D., Tipton, K. F., Tsai, M. D., Westerhoff, H. V., Wittig, U., Wohlgemuth, R. & Kettner, C., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Enzymes
2 Citations
Neurotransmitter Agents
Sulfotransferases
Catechin
Allosteric Site
Binding Sites

The NSAID allosteric site of human cytosolic sulfotransferases

Wang, T., Cook, I. & Leyh, T. S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 49, p. 20305-20312 8 p.

Research output: Contribution to journalArticle

Allosteric Site
Sulfotransferases
Anti-Inflammatory Agents
Pharmaceutical Preparations
Mefenamic Acid
4 Citations

Controlling Sulfuryl-Transfer Biology

Cook, I., Wang, T., Wang, W., Kopp, F., Wu, P. & Leyh, T. S., May 19 2016, In : Cell Chemical Biology. 23, 5, p. 579-586 8 p.

Research output: Contribution to journalArticle

Sulfotransferases
Sulfonation
Estrogen Receptors
Phosphoadenosine Phosphosulfate
Selective Estrogen Receptor Modulators