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  • 2 Similar Profiles
Enzymes Medicine & Life Sciences
Sulfates Medicine & Life Sciences
Sulfate Adenylyltransferase Medicine & Life Sciences
Substrates Chemical Compounds
Guanosine Triphosphate Medicine & Life Sciences
Sulfotransferases Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences

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Grants 1990 2020

Allosteric Regulation
Sulfotransferases
Protein Isoforms
Dopamine
Small Molecule Libraries
Sulfotransferases
Substrates
Metabolism
Enzymes
Pharmaceutical Preparations

The Mevalonate Pathway in Streptococcus

Leyh, T. S.

National Institutes of Health

4/1/063/31/12

Project: Research projectResearch Project

Mevalonic Acid
Streptococcus pneumoniae
Streptococcus
mevalonate kinase
Anti-Bacterial Agents

SULFURYL-TRANSFER--THE HUMAN ESTROGEN SULFOTRANSFERASE

Leyh, T. S.

National Institutes of Health

2/1/001/31/05

Project: Research projectResearch Project

Estrogens
estrone sulfotransferase
Conjugated (USP) Estrogens
Sulfotransferases
Estrogen Replacement Therapy

SULFATE ADENYLATION--BIOCHEMISTRY AND ENZYMOLOGY

Leyh, T. S.

National Institutes of Health

9/2/953/31/14

Project: Research projectResearch Project

Biochemistry
Sulfates
Adenosine Triphosphate
Enzymes
PAPS synthetase

Publications 1980 2017

  • 1841 Citations
  • 23 h-Index
  • 78 Article
Sulfonation
Neurotransmitter Agents
sapropterin
monoamine-sulfating phenol sulfotransferase
Sulfotransferases

Controlling Sulfuryl-Transfer Biology

Cook, I., Wang, T., Wang, W., Kopp, F., Wu, P. & Leyh, T. S. May 19 2016 In : Cell Chemical Biology. 23, 5, p. 579-586 8 p.

Research output: Research - peer-reviewArticle

Sulfotransferases
Estrogen Receptors
Sulfonation
Phosphoadenosine Phosphosulfate
Selective Estrogen Receptor Modulators
2 Citations

Isozyme Specific Allosteric Regulation of Human Sulfotransferase 1A1

Wang, T., Cook, I. & Leyh, T. S. Jul 26 2016 In : Biochemistry. 55, 29, p. 4036-4046 11 p.

Research output: Research - peer-reviewArticle

Allosteric Regulation
Isoenzymes
Nucleotides
epigallocatechin gallate
human SULT1A1 protein
3 Citations

Minireview design and interpretation of human sulfotransferase a1 assays

Wang, T., Cook, I. & Leyh, T. S. Apr 1 2016 In : Drug Metabolism and Disposition. 44, 4, p. 481-484 4 p.

Research output: Research - peer-reviewArticle

Sulfotransferases
Phosphoadenosine Phosphosulfate
Catalysis
Catalytic Domain
Nucleotides
3 Citations

The structure of the catechin-binding site of human sulfotransferase 1A1

Cook, I., Wang, T., Girvin, M. & Leyh, T. S. Dec 13 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14312-14317 6 p.

Research output: Research - peer-reviewArticle

Catechin
Binding Sites
Proteins
human SULT1A1 protein
epigallocatechin gallate