Projects per year
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- 4 Similar Profiles
Inbred NOD Mouse
Medicine & Life Sciences
Type 1 Diabetes Mellitus
Medicine & Life Sciences
T-Lymphocytes
Medicine & Life Sciences
Peptides
Medicine & Life Sciences
Transgenic Mice
Medicine & Life Sciences
Papilloma
Medicine & Life Sciences
Human papillomavirus 11
Medicine & Life Sciences
Antigens
Medicine & Life Sciences
Network
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Grants 2003 2023
An immunotherapeutic strategy for the induction and stabilization of remission in type 1 diabetes
Almo, S. C. & DiLorenzo, T. P.
9/15/18 → 7/31/21
Project: Research project › Research Project
Remission Induction
Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Immunological Synapses
Structural, functional, and mechanistic anlaysis of autoreactive CD8 T cells
Almo, S. C. & DiLorenzo, T. P.
2/8/18 → 1/31/23
Project: Research project › Research Project
T-Lymphocytes
Alleles
T-Cell Antigen Receptor
Type 1 Diabetes Mellitus
Peptides
CD8 T Cell Epitope Mapping Using Mice Expressing HLA-A2 and a Human Autoantigen
4/16/15 → 3/31/18
Project: Research project › Small Research Grants
Epitope Mapping
HLA-A2 Antigen
T-Lymphocyte Epitopes
Autoantigens
T-Lymphocytes
T Cell Tolerance by DEC-205-mediated Islet Antigen Delivery to Dendritic Cells
9/20/11 → 8/31/18
Project: Research project › Research Project
Dendritic Cells
T-Lymphocytes
Antigens
Type 1 Diabetes Mellitus
Proinsulin
T Cell Tolerance by DEC-205-mediated Islet Antigen Delivery to Dendritic Cells
6/1/10 → 5/31/12
Project: Research project › High Priority, Short Term Project Award
Dendritic Cells
Inbred NOD Mouse
T-Lymphocytes
Antigens
Type 1 Diabetes Mellitus
Publications 1989 2018
HLA-B*39: 06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression
Schloss, J., Ali, R., Racine, J. J., Chapman, H. D., Serreze, D. V. & DiLorenzo, T. P., May 15 2018, In : Journal of Immunology. 200, 10, p. 3353-3363 11 p.Research output: Contribution to journal › Article
HLA-B Antigens
Type 1 Diabetes Mellitus
Insulin
T-Lymphocytes
Inbred NOD Mouse
Improved murine MHC-deficient HLA transgenic NOD mouse models for type 1 diabetes therapy development
Racine, J. J., Stewart, I., Ratiu, J., Christianson, G., Lowell, E., Helm, K., Allocco, J., Maser, R. S., Chen, Y. G., Lutz, C. M., Roopenian, D., Schloss, J., DiLorenzo, T. P. & Serreze, D. V., May 1 2018, In : Diabetes. 67, 5, p. 923-935 13 p.Research output: Contribution to journal › Article
Inbred NOD Mouse
Type 1 Diabetes Mellitus
Transgenic Mice
T-Lymphocytes
Clustered Regularly Interspaced Short Palindromic Repeats
An HLA-transgenic mouse model of type 1 diabetes that incorporates the reduced but not abolished thymic insulin expression seen in patients
Babad, J., Ali, R., Schloss, J. & DiLorenzo, T. P., 2016, In : Journal of Diabetes Research. 2016, 7959060.Research output: Contribution to journal › Article
Type 1 Diabetes Mellitus
Transgenic Mice
Insulin
HLA-A Antigens
Major Histocompatibility Complex
Bridging mice to men: Using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans
Serreze, D. V., Niens, M., Kulik, J. & DiLorenzo, T. P., May 1 2016, In : Methods in Molecular Biology. 1438, p. 137-151 15 p.Research output: Contribution to journal › Review article
Type 1 Diabetes Mellitus
Transgenic Mice
Inbred NOD Mouse
T-Lymphocytes
Major Histocompatibility Complex
Characterization of the peptide binding specificity of the HLA class I alleles B*38: 01 and B*39:06
Sidney, J., Schloss, J., Moore, C., Lindvall, M., Wriston, A., Hunt, D. F., Shabanowitz, J., DiLorenzo, T. P. & Sette, A., Mar 1 2016, In : Immunogenetics. 68, 3, p. 231-236 6 p.Research output: Contribution to journal › Article
Alleles
Peptides