• 2819 Citations
  • 31 h-Index
1989 …2023
If you made any changes in Pure, your changes will be visible here soon.

Publications 1989 2019

  • 2819 Citations
  • 31 h-Index
  • 68 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Review article
2019

The evolving landscape of autoantigen discovery and characterization in type 1 diabetes

Purcell, A. W., Sechi, S. & DiLorenzo, T. P., Jan 1 2019, In : Diabetes. 68, 5, p. 879-886 8 p.

Research output: Contribution to journalArticle

Open Access
Autoantigens
Type 1 Diabetes Mellitus
Antigens
Autoantibodies
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
2018
2 Citations (Scopus)

HLA-B*39: 06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression

Schloss, J., Ali, R., Racine, J. J., Chapman, H. D., Serreze, D. V. & DiLorenzo, T. P., May 15 2018, In : Journal of Immunology. 200, 10, p. 3353-3363 11 p.

Research output: Contribution to journalArticle

HLA-B Antigens
Type 1 Diabetes Mellitus
Insulin
T-Lymphocytes
Inbred NOD Mouse
3 Citations (Scopus)

Improved murine MHC-deficient HLA transgenic NOD mouse models for type 1 diabetes therapy development

Racine, J. J., Stewart, I., Ratiu, J., Christianson, G., Lowell, E., Helm, K., Allocco, J., Maser, R. S., Chen, Y. G., Lutz, C. M., Roopenian, D., Schloss, J., DiLorenzo, T. P. & Serreze, D. V., May 1 2018, In : Diabetes. 67, 5, p. 923-935 13 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
Transgenic Mice
T-Lymphocytes
HLA-B39 Antigen
2016
1 Citation (Scopus)
Type 1 Diabetes Mellitus
Transgenic Mice
Insulin
Major Histocompatibility Complex
varespladib methyl
5 Citations (Scopus)

Bridging mice to men: Using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans

Serreze, D. V., Niens, M., Kulik, J. & DiLorenzo, T. P., May 1 2016, In : Methods in Molecular Biology. 1438, p. 137-151 15 p.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Transgenic Mice
Inbred NOD Mouse
T-Lymphocytes
Major Histocompatibility Complex
3 Citations (Scopus)

Characterization of the peptide binding specificity of the HLA class I alleles B*38: 01 and B*39:06

Sidney, J., Schloss, J., Moore, C., Lindvall, M., Wriston, A., Hunt, D. F., Shabanowitz, J., DiLorenzo, T. P. & Sette, A., Mar 1 2016, In : Immunogenetics. 68, 3, p. 231-236 6 p.

Research output: Contribution to journalArticle

Alleles
Peptides
14 Citations (Scopus)

Delivery of siRNAs to dendritic cells using DEC205-targeted lipid nanoparticles to inhibit immune responses

Katakowski, J. A., Mukherjee, G., Wilner, S. E., Maier, K. E., Harrison, M. T., DiLorenzo, T. P., Levy, M. & Palliser, D., Feb 1 2016, In : Molecular Therapy. 24, 1, p. 146-155 10 p.

Research output: Contribution to journalArticle

Nanoparticles
Dendritic Cells
Lipids
Gene Knockdown Techniques
Lymphocytes
5 Citations (Scopus)

Genetically modified human CD4+ T cells can be evaluated in vivo without lethal graft-versus-host disease

Ali, R., Babad, J., Follenzi, A., Gebe, J. A., Brehm, M. A., Nepom, G. T., Shultz, L. D., Greiner, D. L. & DiLorenzo, T. P., Aug 1 2016, In : Immunology. 148, 4, p. 339-351 13 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
T-Lymphocytes
T-Cell Antigen Receptor
HLA-DR4 Antigen
Genetic Transduction
2015
13 Citations (Scopus)

Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice

Babad, J., Mukherjee, G., Follenzi, A., Ali, R., Roep, B. O., Shultz, L. D., Santamaria, P., Yang, O. O., Goldstein, H., Greiner, D. L. & DiLorenzo, T. P., Mar 1 2015, In : Clinical and Experimental Immunology. 179, 3, p. 398-413 16 p.

Research output: Contribution to journalArticle

HLA Antigens
Transgenic Mice
T-Lymphocytes
Survival
T-Cell Antigen Receptor
4 Citations (Scopus)

Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice

Mukherjee, G., Chaparro, R. J., Schloss, J., Smith, C., Bando, C. D. & DiLorenzo, T. P., Apr 1 2015, In : Immunology. 144, 4, p. 631-640 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Glucagon
T-Lymphocytes
Type 1 Diabetes Mellitus
Islets of Langerhans
2014
12 Citations (Scopus)

Compensatory Mechanisms Allow Undersized Anchor-Deficient Class i MHC Ligands to Mediate Pathogenic Autoreactive T Cell Responses

Lamont, D., Mukherjee, G., Kumar, P. R., Samanta, D., McPhee, C. G., Kay, T. W. H., Almo, S. C., DiLorenzo, T. P. & Serreze, D. V., Sep 1 2014, In : Journal of Immunology. 193, 5, p. 2135-2146 12 p.

Research output: Contribution to journalArticle

Ligands
T-Lymphocytes
Inbred NOD Mouse
Peptides
Crystallography
2013
8 Citations (Scopus)

DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8+ T cells independently of PD-1 and PD-L1

Mukherjee, G., Geliebter, A., Babad, J., Santamaria, P., Serreze, D. V., Freeman, G. J., Tarbell, K. V., Sharpe, A. & DiLorenzo, T. P., Nov 2013, In : International Immunology. 25, 11, p. 651-660 10 p., dxt031.

Research output: Contribution to journalArticle

Dendritic Cells
T-Lymphocytes
Antigens
Inbred NOD Mouse
Glucose-6-Phosphatase
2012
6 Citations (Scopus)

Beyond HLA-A*0201: New HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8 + T cell epitopes

Antal, Z., Baker, J. C., Smith, C., Jarchum, I., Babad, J., Mukherjee, G., Yang, Y., Sidney, J., Sette, A., Santamaria, P. & DiLorenzo, T. P., Jun 1 2012, In : Journal of Immunology. 188, 11, p. 5766-5775 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
T-Lymphocyte Epitopes
C-Peptide
Type 1 Diabetes Mellitus
Transgenic Mice
2011
12 Citations (Scopus)
Type 1 Diabetes Mellitus
Antigens
Inbred NOD Mouse
Insulin
Major Histocompatibility Complex
11 Citations (Scopus)

Structural and functional characterization of a single-chain peptide - MHC molecule that modulates both naive and activated CD8 + T cells

Samanta, D., Mukherjee, G., Ramagopal, U. A., Chaparro, R. J., Nathenson, S. G., DiLorenzo, T. P. & Almo, S. C., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13682-13687 6 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Peptides
Cytotoxic T-Lymphocytes
Autoimmune Diseases
Antigens
2010
33 Citations (Scopus)

An update on the use of NOD mice to study autoimmune (Type 1) diabetes

Chaparro, R. J. & DiLorenzo, T. P., Nov 2010, In : Expert Review of Clinical Immunology. 6, 6, p. 939-955 17 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
Disease Susceptibility
Genetic Association Studies
Inflammation
4 Citations (Scopus)

Bridging mice to men: Using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans

Serreze, D. V., Niens, M., Kulik, J. & DiLorenzo, T. P., 2010, Methods in Molecular Biology. Vol. 602. p. 119-134 16 p. (Methods in Molecular Biology; vol. 602).

Research output: Chapter in Book/Report/Conference proceedingChapter

Type 1 Diabetes Mellitus
Transgenic Mice
Inbred NOD Mouse
T-Lymphocytes
Major Histocompatibility Complex
13 Citations (Scopus)

Ins2 deficiency augments spontaneous HLA-A*0201-restricted T Cell responses to insulin

Jarchum, I. & DiLorenzo, T. P., Jan 15 2010, In : Journal of Immunology. 184, 2, p. 658-665 8 p.

Research output: Contribution to journalArticle

Insulin
T-Lymphocytes
Type 1 Diabetes Mellitus
HLA-A*02:01 antigen
Alleles
2 Citations (Scopus)

Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect

Brims, D. R., Qian, J., Jarchum, I., Mikesh, L., Palmieri, E., Ramagopal, U. A., Malashkevich, V. N., Chaparro, R. J., Lund, T., Hattori, M., Shabanowitz, J., Hunt, D. F., Nathenson, S. G., Almo, S. C. & DiLorenzo, T. P., Jan 21 2010, In : International Immunology. 22, 3, p. 191-203 13 p., dxp127.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Occupations
T-Lymphocytes
Peptides
Inbred NOD Mouse
28 Citations (Scopus)

T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes

Babad, J., Geliebter, A. & DiLorenzo, T. P., Dec 2010, In : Immunology. 131, 4, p. 459-465 7 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Autoantigens
Type 1 Diabetes Mellitus
T-Lymphocytes
Viral Tumor Antigens
3 Citations (Scopus)

The benefit of self-control

Santambrogio, L. & DiLorenzo, T. P., Jul 2010, In : Immunology and Cell Biology. 88, 5, p. 513-514 2 p.

Research output: Contribution to journalArticle

Self Tolerance
Histocompatibility Antigens Class II
Autoantigens
Antigen Presentation
Lymphocyte Activation
19 Citations (Scopus)

The immunotherapeutic potential of dendritic cells in type 1 diabetes

Mukherjee, G. & DiLorenzo, T. P., Aug 2010, In : Clinical and Experimental Immunology. 161, 2, p. 197-207 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Dendritic Cells
Antigens
Regulatory T-Lymphocytes
T-Lymphocytes
2009
6 Citations (Scopus)

Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic β-cells to correct diabetes in allogeneic mice

Kojaoghlanian, T., Joseph, A., Follenzi, A., Zheng, J. H., Leiser, M., Fleischer, N., Horwitz, M. S., DiLorenzo, T. P. & Goldstein, H., 2009, In : Gene Therapy. 16, 3, p. 340-348 9 p.

Research output: Contribution to journalArticle

Immunosuppressive Agents
Proteins
Genetic Engineering
Lentivirus
SCID Mice
2008
17 Citations (Scopus)

Efficient culture of CD8+ T cells from the islets of NOD mice and their use for the study of autoreactive specificities

Jarchum, I., Takaki, T. & DiLorenzo, T. P., Nov 30 2008, In : Journal of Immunological Methods. 339, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
Islets of Langerhans
T-Lymphocytes
Insulin-Secreting Cells
2 Citations (Scopus)

HLA class I supertypes in type 1 diabetic children in an urban children's hospital

Antal, Z., Jarchum, I. & DiLorenzo, T. P., Dec 2008, Annals of the New York Academy of Sciences. Vol. 1150. p. 86-89 4 p. (Annals of the New York Academy of Sciences; vol. 1150).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

T-cells
Urban Hospitals
Medical problems
Epitopes
Alleles
53 Citations (Scopus)

Identification of novel IGRP epitopes targeted in type 1 diabetes patients

Jarchum, I., Nichol, L., Trucco, M., Santamaria, P. & DiLorenzo, T. P., Jun 2008, In : Clinical Immunology. 127, 3, p. 359-365 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Epitopes
Inbred NOD Mouse
T-Lymphocytes
HLA-A2 Antigen
68 Citations (Scopus)

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity

Joseph, A., Jian, H. Z., Follenzi, A., DiLorenzo, T. P., Sango, K., Hyman, J., Chen, K., Piechocka-Trocha, A., Brander, C., Hooijberg, E., Vignali, D. A., Walker, B. D. & Goldstein, H., Mar 2008, In : Journal of Virology. 82, 6, p. 3078-3089 12 p.

Research output: Contribution to journalArticle

T-Cell Receptor Genes
cytotoxic T-lymphocytes
Cytotoxic T-Lymphocytes
Human immunodeficiency virus 1
HIV-1
7 Citations (Scopus)

Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells

Chaparro, R. J., Burton, A. R., Serreze, D. V., Vignali, D. A. A. & DiLorenzo, T. P., Jun 1 2008, In : Journal of Immunological Methods. 335, 1-2, p. 106-115 10 p.

Research output: Contribution to journalArticle

Histocompatibility Antigens Class I
Type 1 Diabetes Mellitus
T-Lymphocytes
Inbred NOD Mouse
Viral Tumor Antigens
99 Citations (Scopus)

Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice

Mukhopadhaya, A., Hanafusa, T., Jarchum, I., Chen, Y. G., Iwai, Y., Serreze, D. V., Steinman, R. M., Tarbell, K. V. & DiLorenzo, T. P., Apr 29 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 17, p. 6374-6379 6 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Dendritic Cells
T-Lymphocytes
Antigens
Type 1 Diabetes Mellitus
2007
52 Citations (Scopus)

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

Chattopadhyay, K., Ramagopal, U. A., Mukhopadhaya, A., Malashkevich, V. N., DiLorenzo, T. P., Brenowitz, M. D., Nathenson, S. G. & Almo, S. C., Dec 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 49, p. 19452-19457 6 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factors
Glucocorticoids
Regulatory T-Lymphocytes
T-Lymphocytes
17 Citations (Scopus)

"Humanized" HLA transgenic NOD mice to identify pancreatic β cell autoantigens of potential clinical relevance to type 1 diabetes

Serreze, D. V., Marron, M. P. & DiLorenzo, T. P., Apr 2007, Annals of the New York Academy of Sciences. Vol. 1103. p. 103-111 9 p. (Annals of the New York Academy of Sciences; vol. 1103).

Research output: Chapter in Book/Report/Conference proceedingChapter

Inbred NOD Mouse
Autoantigens
Medical problems
Type 1 Diabetes Mellitus
T-cells
74 Citations (Scopus)

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator

Forestier, C., Takaki, T., Molano, A., Im, J. S., Baine, I., Jerud, E. S., Illarionov, P., Ndonye, R., Howell, A. R., Santamaria, P., Besra, G. S., DiLorenzo, T. P. & Porcelli, S. A., Feb 1 2007, In : Journal of Immunology. 178, 3, p. 1415-1425 11 p.

Research output: Contribution to journalArticle

Galactosylceramides
Inbred NOD Mouse
Natural Killer T-Cells
Cytokines
Dendritic Cells
38 Citations (Scopus)

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice

Jarchum, I., Baker, J. C., Yamada, T., Takaki, T., Marron, M. P., Serreze, D. V. & DiLorenzo, T. P., Oct 2007, In : Diabetes. 56, 10, p. 2551-2560 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Transgenic Mice
Insulin
T-Lymphocytes
Peptides
90 Citations (Scopus)

Structural genomics of protein phosphatases

Almo, S. C., Bonanno, J. B., Sauder, J. M., Emtage, S., DiLorenzo, T. P., Malashkevich, V., Wasserman, S. R., Swaminathan, S., Eswaramoorthy, S., Agarwal, R., Kumaran, D., Madegowda, M., Ragumani, S., Patskovsky, Y., Alvarado, J., Ramagopal, U. A., Faber-Barata, J., Chance, M. R., Sali, A., Fiser, A. & 3 others, Zhang, Z. Y., Lawrence, D. S. & Burley, S. K., Sep 2007, In : Journal of Structural and Functional Genomics. 8, 2-3, p. 121-140 20 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
Genomics
Pathogens
National Institute of General Medical Sciences (U.S.)
African Trypanosomiasis
103 Citations (Scopus)

T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface

Cao, E., Zang, X., Ramagopal, U. A., Mukhopadhaya, A., Fedorov, A., Fedorov, E., Zencheck, W. D., Lary, J. W., Cole, J. L., Deng, H., Xiao, H., DiLorenzo, T. P., Allison, J. P., Nathenson, S. G. & Almo, S. C., Mar 23 2007, In : Immunity. 26, 3, p. 311-321 11 p.

Research output: Contribution to journalArticle

Mucin-3
Galectins
Immunoglobulins
Ligands
T-Lymphocytes
177 Citations (Scopus)

Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

DiLorenzo, T. P., Peakman, M. & Roep, B. O., Apr 2007, In : Clinical and Experimental Immunology. 148, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

T-Lymphocyte Epitopes
Type 1 Diabetes Mellitus
Epitopes
T-Lymphocytes
Antigens
2006
86 Citations (Scopus)

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes

Takaki, T., Marron, M. P., Mathews, C. E., Guttmann, S. T., Bottino, R., Trucco, M., DiLorenzo, T. P. & Serreze, D. V., Mar 1 2006, In : Journal of Immunology. 176, 5, p. 3257-3265 9 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Autoantigens
Type 1 Diabetes Mellitus
T-Lymphocytes
Peptides
1 Citation (Scopus)
beta 2-Microglobulin
Antigen Presentation
Type 1 Diabetes Mellitus
Thermodynamics
Peptides
2005
87 Citations (Scopus)

Developmental control of CD8+ T cell-avidity maturation in autoimmune diabetes

Han, B., Serra, P., Yamanouchi, J., Amrani, A., Elliott, J. F., Dickie, P., DiLorenzo, T. P. & Santamaria, P., Jul 2005, In : Journal of Clinical Investigation. 115, 7, p. 1879-1887 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
T-Lymphocytes
Autoimmunity
Islets of Langerhans
Antigens
Inbred NOD Mouse
T-Lymphocytes
63 Citations (Scopus)

The good turned ugly: Immunopathogenic basis for diabetogenic CD8 + T cells in NOD mice

DiLorenzo, T. P. & Serreze, D. V., Apr 2005, In : Immunological Reviews. 204, p. 250-263 14 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
T-Lymphocytes
Major Histocompatibility Complex
Islets of Langerhans
2004
99 Citations (Scopus)

Individual nonobese diabetic mice exhibit unique patterns of CD8 + T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase

Lieberman, S. M., Takaki, T., Han, B., Santamaria, P., Serreze, D. V. & DiLorenzo, T. P., Dec 1 2004, In : Journal of Immunology. 173, 11, p. 6727-6734 8 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Inbred NOD Mouse
Phosphotransferases
T-Lymphocytes
Antigens
35 Citations (Scopus)

MHC Class II Molecules Play a Role in the Selection of Autoreactive Class I-Restricted CD8 T Cells that are Essential Contributors to Type 1 Diabetes Development in Nonobese Diabetic Mice

Serreze, D. V., Holl, T. M., Marron, M. P., Graser, R. T., Johnson, E. A., Choisy-Rossi, C., Slattery, R. M., Lieberman, S. M. & DiLorenzo, T. P., Jan 15 2004, In : Journal of Immunology. 172, 2, p. 871-879 9 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
T-Lymphocytes
Haplotypes
Clone Cells
24 Citations (Scopus)

Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4

Takaki, T., Lieberman, S. M., Holl, T. M., Han, B., Santamaria, P., Serreze, D. V. & DiLorenzo, T. P., Aug 15 2004, In : Journal of Immunology. 173, 4, p. 2530-2541 12 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
T-Lymphocytes
Type 1 Diabetes Mellitus
Bone Marrow Diseases
Congenic Mice
2003
121 Citations (Scopus)

A comprehensive guide to antibody and T-cell responses in type 1 diabetes

Lieberman, S. M. & DiLorenzo, T. P., Nov 2003, In : Tissue Antigens. 62, 5, p. 359-377 19 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
T-Lymphocytes
Antibodies
Antigens
Inbred NOD Mouse
306 Citations (Scopus)

Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes

Lieberman, S. M., Evans, A. M., Han, B., Takaki, T., Vinnitskaya, Y., Caldwell, J. A., Serreze, D. V., Shabanowitz, J., Hunt, D. F., Nathenson, S. G., Santamaria, P. & DiLorenzo, T. P., Jul 8 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 14, p. 8384-8388 5 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
T-Lymphocytes
Antigens
Population
Glucose-6-Phosphatase
2002
33 Citations (Scopus)

During the early prediabetic period in NOD mice, the pathogenic CD8+ T-cell population comprises multiple antigenic specificities

DiLorenzo, T. P., Lieberman, S. M., Takaki, T., Honda, S., Chapman, H. D., Santamaria, P., Serreze, D. V. & Nathenson, S. G., Dec 1 2002, In : Clinical Immunology. 105, 3, p. 332-341 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Epitopes
T-Lymphocytes
Clone Cells
Peptides
2001
35 Citations (Scopus)

Autoreactive Diabetogenic T-Cells in NOD Mice Can Efficiently Expand from a Greatly Reduced Precursor Pool

Serreze, D. V., Johnson, E. A., Chapman, H. D., Graser, R. T., Marron, M. P., DiLorenzo, T. P., Silveira, P., Yoshimura, Y., Nathenson, S. G. & Joyce, S., Sep 2001, In : Diabetes. 50, 9, p. 1992-2000 9 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
T-Lymphocytes
T-Cell Antigen Receptor
Lymphocytic choriomeningitis virus
Type 1 Diabetes Mellitus
5 Citations (Scopus)

Hapten addition to an MHC class I-binding peptide causes substantial adjustments of the TCR structure of the responding CD8+ T cells

Honda, S., Zhang, W., Kalergis, A. M., DiLorenzo, T. P., Wang, F. & Nathenson, S. G., Oct 15 2001, In : Journal of Immunology. 167, 8, p. 4276-4285 10 p.

Research output: Contribution to journalArticle

Haptens
T-Lymphocytes
Peptides
Vesicular Stomatitis
Nucleoproteins
4 Citations (Scopus)

Immunobiological analysis of TCR single-chain transgenic mice reveals new possibilities for interaction between CDR3α and an antigenic peptide bound to MHC class I

Zhang, W., Honda, S., Wang, F., DiLorenzo, T. P., Kalergis, A. M., Ostrov, D. A. & Nathenson, S. G., Oct 15 2001, In : Journal of Immunology. 167, 8, p. 4396-4404 9 p.

Research output: Contribution to journalArticle

Transgenic Mice
Peptides
vesicular stomatitis virus nucleoprotein (52-59)
T-Cell Antigen Receptor Specificity
T-Lymphocytes