• 6773 Citations
  • 46 h-Index
1978 …2023
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Personal profile

Keywords

  • RZ Other systems of medicine
  • Microbiome
  • Health
  • orphan nuclear receptors
  • inflammatory bowel disease
  • colon cancer
  • probiotics

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 1978 2023

Colitis
Colorectal Neoplasms
Toll-Like Receptor 4
Inflammation
Colonic Neoplasms

Development of Novel Drugs to Alleviate CPT-11 Toxicity

Mani, S. & Redinbo, M.

National Institutes of Health

4/1/123/31/17

Project: Research projectResearch Project

irinotecan
Glucuronidase
Pharmaceutical Preparations
Neoplasms
Pharmacology

6th International Conference on SBDS

Mani, S. & Liu, J. M.

National Institutes of Health

6/1/116/30/12

Project: Research projectConference

Inborn Genetic Diseases
Bone Marrow
Hematopoiesis
Research Personnel
Medicine

Chemical Modulation of Orphan Nuclear Receptor Function

Mani, S.

National Institutes of Health

8/13/095/31/15

Project: Research projectResearch Project

Orphan Nuclear Receptors
Ketoconazole
Ligands
pregnane X receptor
Molecular Biology

HEMATOPOIESIS IN RETROVIRUS INFECTED SIMIANS

Mani, S., Reimann, K., Weiss, N. M., Goldberg, L., Schuster, C., Rabinovich, C. E., Kremser, C., Buse, J., Solway, J., Josephson, M., Asplin, J., Herbst, A. L., Lashner, B., Mazzone, T., Kreiter, M., Dewit, H., Brown, F. D., Scoeller, D., Rajfer, S., Pononsky, K., Richman, D., Douglas, F. L., Baron, J. M., Thistlethwaite, J. R., Jones, T., Meltzer, H. Y., Johanson, C. E., Aycinena, P., Chelmickaschorr, E. V. A., Rosenberg, I., Arcilla, R., Zacny, J., Roos, R. P., Polansky, K., Scany, A. M., Tartof, D., Davidson, N., Lichtor, J. L., Knowles, J. B., Jonas, R. B., January, C., Hall, J., Roizan, N., Voke, T., Cara, J., Cuttler, L., Senay, E., Beebe, C. A., Loy, G., Palonsky, K. S., Huttenlocher, P., Barron, W. M., Kaplan, E., Benca, R., Antel, J., Murphy, M. B., Degroot, L., Baker, A. L., Schueller, D., Cohen, L., Burstein, S., Roizen, N., Fellner, S. K., Samuels, B., Sommerfeld, E., Lau, K., Kaplan, E., Landau, R., Kirschner, B., Saper, C., Hopkins, J., Reder, A. T., Berkelhammer, C., Rose, R. P., Apfelbaum, J., Jonghorbani, M., Schuette, S., Pliskin, N., Scanu, A., Sarne, D., Moll, G. W., Robertson, G. L., Goldman, M., Crayton, J., Sitrin, M., Golomb, H., Richards, J., Jaspar, J., Little, A. G., Jaspan, J. B., Bergenstal, R., Rubenstein, A. H., Roizen, M., Lang, R., Cura, J., Rolzen, M., Fang, V. S., Lindheimer, M., Chait, L., Whitington, P., King, D., Yost, M., Hellman, S., Arnason, B., Sarpong, S., Johnson, D., Draganich, L. F., McClintock, M., Ndukwu, I., Getz, G. S., Keenan, K. E., Steele, G., Murray, P., Kindler, H., Conjeevaram, H., Olopade, O., McNally, B., Ratain, M., Kyle, J., King, A., Yuan, C., Vogelzang, N., Ehrenpreis, E., Cook, E., Weir, B., [No Value], F. L., Vokes, T., Madara, J., Vokes, E., Woodle, E. S., Covert, R., Ehrman, D., Lauderdale, D., Gajewski, T., Ober, C., McBurnett, K., Clark, M., Brady, L., Rosenfield, R., Brady, L., Ober, C., Hanauer, S. B., McBurnett, K., Keenan, K. E., Murray, P., van Cauter, E. V. E., Kindler, H., Rabinovich, C. D., Conjeevaram, H., Lauderdale, D., Refetoff, S., Schilsky, R., Weiss, R., Olopade, O., Bell, G., Ehrman, D., Polonsky, K., McNally, B., De, H., Barnes, R., Ehramann, D., Ratain, M., Cho, J., Clark, M., Gajewski, T., Kyle, J., King, A., Yuan, C., Vogelzang, N., Ehrenpreis, E., Cook, E., Favus, M., Ehrmann, D., David, F., Refetoff, S., Sokoloff, M., Phillipson, L., Hall, J. B., Radovick, S., Vogelzang, N., Kim, K., Dachman, A., Owley, T., Alverdy, J. C., Mc Closkey, M., Te, H., Rosenfield, R., Garfinkel, M., Cocca, E. F., McConville, J., Ober, C., White, S., van Cauter, E. V. E., Weiss, R., McNally, E., Royce, L., Lipton, R. B., De, H., Cho, J., Penev, P., King, A., Yuan, C., Ehrmann, D., Philipson, L. H., Favus, M., Burnett, D., Utset, T., Ratain, M., Sperling, A. I., Stephenson, M., Lahn, B., Noth, I., Phan, K. L., Refetoff, S., Pannain, S., Nicolae, D. L., Gomberg-Maitland, M., Bell, G., [No Value], N. J., Burnet, D., Tasali, E., Olopade, F., Clark, M., Maitland, M. L., Le Grange, D., Kusher, R., Byrne, M., Clarke, B., Umans, J., Ober, C., Aikens, J., Herold, K., Schoeller, D. A., Gerber, G., Lichtor, J., Wagner-Weiner, L., Yurk, H., Scholler, D., Albert, D., Fleming, G., Bartosh, S., Kushner, R. F., Foss, J., Rosenfield, R. L., Hanauer, S., Favus, M. J., van Cauter, E. V. E., Rabinovich, C. D., Refetoff, S., Schilsky, R., Weiss, R., Bell, G., Polonsky, K., De, H., Barnes, R. B., Ehramann, D., Cho, J., Ehrmann, D., Weiss, N. M., Rabinovich, C. E., Herbst, A. L., Brown, F. D., Douglas, F. L., Baron, J. M., Thistlethwaite, J. R., Johanson, C. E., Chelmickaschorr, E. V. A., Roos, R. P., Scany, A. M., Lichtor, J. L., Knowles, J. B., Jonas, R. B., Beebe, C. A., Palonsky, K. S., Barron, W. M., Aycinena, P., Murphy, M. B., Baker, A. L., Robertson, G. L., Fellner, S. K., Reder, A. T., Fang, V. S., Rose, R. P., Moll, G. W., Little, A. G., Jaspan, J. B., Rubenstein, A. H., Ndukwu, I., [No Value], F. L., Woodle, E. S., Hanauer, S. B., van Cauter, E. V. E., Hall, J. B., Alverdy, J. C., van Cauter, E. V. E., Lipton, R. B., Sperling, A. I., Phan, K. L., [No Value], N. J., Maitland, M. L., Dachman, A., Owley, T., Alverdy, J. C., Mc Closkey, M., Te, H., Rosenfield, R., Garfinkel, M., Cocca, E. F., McConville, J., Coe, F., Ober, C., White, S., van Cauter, E. V. E., Weiss, R., McNally, E., Royce, L., Lipton, R. B., De, H., Cho, J., Vokes, T., Penev, P., King, A., Yuan, C., Ehrmann, D., Kusher, R., Byrne, M., Clarke, B., Umans, J., Ober, C., Aikens, J., Herold, K., Schoeller, D. A., Gerber, G., Lichtor, J., Wagner-Weiner, L., Yurk, H., Scholler, D., Albert, D., Fleming, G., Bartosh, S., Kushner, R. F., Foss, J., Rosenfield, R. L., Hanauer, S., Favus, M. J., van Cauter, E. V. E., Rabinovich, C. D., Refetoff, S., Schilsky, R., Weiss, R., Bell, G., Polonsky, K., De, H., Barnes, R. B., Ehramann, D., Cho, J. & Ehrmann, D.

National Institutes of Health

12/1/782/28/11

Project: Research projectResearch Scientist Development Award - Research & Training, General Clinical Research Centers Program

Fluorouracil
Food
Uracil
Tablets
Meals

Publications 1990 2018

  • 6773 Citations
  • 46 h-Index
  • 176 Article
  • 1 Chapter
  • 1 Review article

Methylindoles and methoxyindoles are agonists and antagonists of human aryl hydrocarbon receptor

Stepankova, M., Bartonkova, I., Jiskrova, E., Vrzal, R., Mani, S., Kortagere, S. & Dvorak, Z., Jun 1 2018, In : Molecular Pharmacology. 93, 6, p. 631-644 14 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Inhibitory Concentration 50
Cytochrome P-450 CYP1A1
Reporter Genes
indole
1 Citations

Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis

Huang, K., Mukherjee, S., Desmarais, V., Albanese, J. M., Rafti, E., Draghi, A., Maher, L. A., Khanna, K. M., Mani, S. & Matson, A. P., May 1 2018, In : Pediatric Research. 83, 5, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Theoretical Models
Inflammation
Lithocholic Acid
7 Citations

Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice

Luo, X., Yu, Z., Deng, C., Zhang, J., Ren, G., Sun, A., Mani, S., Wang, Z. & Dou, W., Dec 1 2017, In : Scientific Reports. 7, 1, 16374.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Trinitrobenzenes
Inflammasomes
Toll-Like Receptor 4
Sulfonic Acids
3 Citations

Constitutive androstane receptor regulates the intestinal mucosal response to injury

Hudson, G. M., Flannigan, K. L., Erickson, S. L., Vicentini, F. A., Zamponi, A., Hirota, C. L., Alston, L., Altier, C., Ghosh, S., Rioux, K. P., Mani, S., Chang, T. K. & Hirota, S. A., 2017, In : British Journal of Pharmacology. 174, 12, p. 1857-1871 15 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Xenobiotics
Ulcerative Colitis
Inflammatory Bowel Diseases
Crohn Disease
2 Citations

Microbiota and Breast Cancer

Mani, S., 2017, (Accepted/In press) In : Progress in Molecular Biology and Translational Science.

Research output: Contribution to journalArticle

Microbiota
Breast
Breast Neoplasms
Carcinogenesis
Bacteria