• 7137 Citations
  • 47 h-Index
1978 …2023
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Personal profile


  • RZ Other systems of medicine
  • Microbiome
  • Health
  • orphan nuclear receptors
  • inflammatory bowel disease
  • colon cancer
  • probiotics

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 1978 2023

Colorectal Neoplasms
Toll-Like Receptor 4
Colonic Neoplasms
Halogenated Diphenyl Ethers
Pharmaceutical Preparations

6th International Conference on SBDS

Mani, S. & Liu, J. M.

National Institutes of Health


Project: Research project

Inborn Genetic Diseases
Bone Marrow
Research Personnel
Orphan Nuclear Receptors
pregnane X receptor
Molecular Biology

Publications 1990 2019

  • 7137 Citations
  • 47 h-Index
  • 177 Article
  • 1 Chapter
  • 1 Review article
1 Citation (Scopus)

Belinostat, at Its Clinically Relevant Concentrations, Inhibits Rifampicin-Induced CYP3A4 and MDR1 Gene Expression

Abbott, K. L., Chaudhury, C. S., Chandran, A., Vishveshwara, S., Dvorak, Z., Jiskrova, E., Poulikova, K., Vyhlidalova, B., Mani, S. & Pondugula, S. R., Mar 1 2019, In : Molecular Pharmacology. 95, 3, p. 324-334 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Gene Expression
Combination Drug Therapy
2 Citations (Scopus)

Methylindoles and methoxyindoles are agonists and antagonists of human aryl hydrocarbon receptor

Stepankova, M., Bartonkova, I., Jiskrova, E., Vrzal, R., Mani, S., Kortagere, S. & Dvorak, Z., Jun 1 2018, In : Molecular Pharmacology. 93, 6, p. 631-644 14 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Inhibitory Concentration 50
Cytochrome P-450 CYP1A1
Reporter Genes
2 Citations (Scopus)

Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis

Huang, K., Mukherjee, S., Desmarais, V. M., Albanese, J. M., Rafti, E., Draghi, A., Maher, L. A., Khanna, K. M., Mani, S. & Matson, A. P., May 1 2018, In : Pediatric Research. 83, 5, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Necrotizing Enterocolitis
Toll-Like Receptor 4
Theoretical Models
Lithocholic Acid
12 Citations (Scopus)

Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice

Luo, X., Yu, Z., Deng, C., Zhang, J., Ren, G., Sun, A., Mani, S., Wang, Z. & Dou, W., Dec 1 2017, In : Scientific Reports. 7, 1, 16374.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Toll-Like Receptor 4
Sulfonic Acids
5 Citations (Scopus)

Constitutive androstane receptor regulates the intestinal mucosal response to injury

Hudson, G. M., Flannigan, K. L., Erickson, S. L., Vicentini, F. A., Zamponi, A., Hirota, C. L., Alston, L., Altier, C., Ghosh, S., Rioux, K. P., Mani, S., Chang, T. K. & Hirota, S. A., 2017, In : British Journal of Pharmacology. 174, 12, p. 1857-1871 15 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Ulcerative Colitis
Inflammatory Bowel Diseases
Crohn Disease