• 5391 Citations
  • 44 h-Index
1977 …2019

Research output per year

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Publications

  • 5391 Citations
  • 44 h-Index
  • 96 Article
  • 10 Review article
  • 4 Short survey
  • 1 Foreword/postscript
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Article
2003

Visualization of the target-membrane-inserted fusion protein of semliki forest virus by combined electron microscopy and crystallography

Gibbons, D. L., Erk, I., Reilly, B., Navaza, J., Kielian, M., Rey, F. A. & Lepault, J., Sep 5 2003, In : Cell. 114, 5, p. 573-583 11 p.

Research output: Contribution to journalArticle

84 Scopus citations
2002

Effects of membrane potential and sphingolipid structures on fusion of Semliki Forest virus

Samsonov, A. V., Chatterjee, P. K., Razinkov, V. I., Eng, C. H., Kielian, M. & Cohen, F. S., Dec 1 2002, In : Journal of virology. 76, 24, p. 12691-12702 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Molecular dissection of the Semliki Forest virus homotrimer reveals two functionally distinct regions of the fusion protein

Gibbons, D. L. & Kielian, M., Jan 1 2002, In : Journal of virology. 76, 3, p. 1194-1205 12 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Novel mutations that control the sphingolipid and cholesterol dependence of the semliki forest virus fusion protein

Chatterjee, P. K., Eng, C. H. & Kielian, M., Dec 1 2002, In : Journal of virology. 76, 24, p. 12712-12722 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

The fusion peptide of Semliki Forest virus associates with sterol-rich membrane domains

Ahn, A., Gibbons, D. L. & Kielian, M., Mar 25 2002, In : Journal of virology. 76, 7, p. 3267-3275 9 p.

Research output: Contribution to journalArticle

103 Scopus citations
2001

Differential roles of two conserved glycine residues in the fusion peptide of Semliki Forest Virus

Shome, S. G. & Kielian, M., Jan 1 2001, In : Virology. 279, 1, p. 146-160 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

In vivo generation and characterization of a soluble form of the Semliki Forest virus fusion protein

Lu, Y. E., Eng, C. H., Shome, S. G. & Kielian, M., Aug 23 2001, In : Journal of virology. 75, 17, p. 8329-8339 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2000

Biochemical consequences of a mutation that controls the cholesterol dependence of Semliki Forest virus fusion

Chatterjee, P. K., Vashishtha, M. & Kielian, M., Jul 17 2000, In : Journal of virology. 74, 4, p. 1623-1631 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Formation and characterization of the trimeric form of the fusion protein of Semliki Forest virus

Gibbons, D. L., Ahn, A., Chatterjee, P. K. & Kielian, M., Sep 2 2000, In : Journal of virology. 74, 17, p. 7772-7780 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Semliki forest virus budding: Assay, mechanisms, and cholesterol requirement

Lu, Y. E. & Kielian, M., Sep 2 2000, In : Journal of virology. 74, 17, p. 7708-7719 12 p.

Research output: Contribution to journalArticle

45 Scopus citations
1999

An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusion

Ahn, A., Klimjack, M. R., Chatterjee, P. K. & Kielian, M., Dec 1 1999, In : Journal of virology. 73, 12, p. 10029-10039 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Growth and stability of a cholesterol-independent Semliki Forest virus mutant in mosquitoes

Ahn, A., Schoepp, R. J., Sternberg, D. & Kielian, M., Sep 30 1999, In : Virology. 262, 2, p. 452-456 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
122 Scopus citations
1998

A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit

Vashishtha, M., Phalen, T., Marquardt, M. T., Ryu, J. S., Ng, A. C. & Kielian, M., Jan 12 1998, In : Journal of Cell Biology. 140, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

fus-1, a pH shift mutant of Semliki Forest virus, acts by altering spike subunit interactions via a mutation in the E2 subunit

Glomb-Reinmund, S. & Kielian, M., May 1 1998, In : Journal of virology. 72, 5, p. 4281-4287 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

The role of low pH and disulfide shuffling in the entry and fusion of Semliki Forest virus and Sindbis virus

Glomb-Reinmund, S. & Kielian, M., Sep 1 1998, In : Virology. 248, 2, p. 372-381 10 p.

Research output: Contribution to journalArticle

62 Scopus citations
1997

Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum

Jacobs, N. L., Andemariam, B., Underwood, K. W., Panchalingam, K., Sternberg, D., Kielian, M. & Liscum, L., Oct 1 1997, In : Journal of Lipid Research. 38, 10, p. 1973-1987 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cholesterol-independent targeting of Golgi membrane proteins in insect cells

Rolls, M. M., Marquardt, M. T., Kielian, M. & Machamer, C. E., Jan 1 1997, In : Molecular biology of the cell. 8, 11, p. 2111-2118 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
1996

Cholesterol-depleted cells that are relatively permissive for Semliki Forest virus infection

Marquardt, M. T. & Kielian, M., Oct 1 1996, In : Virology. 224, 1, p. 198-205 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mechanisms of mutations inhibiting fusion and infection by Semliki Forest virus

Kielian, M., Klimjack, M. R., Ghosh, S. & Duffus, W. A., Aug 1996, In : Journal of Cell Biology. 134, 4, p. 863-872 10 p.

Research output: Contribution to journalArticle

Open Access
84 Scopus citations

Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells: Differential effects on endocytosis and lysosomal sorting

Martys, J. L., Wjasow, C., Gangi, D. M., Kielian, M. C., McGraw, T. E. & Backer, J. M., May 20 1996, In : Journal of Biological Chemistry. 271, 18, p. 10953-10962 10 p.

Research output: Contribution to journalArticle

117 Scopus citations
1995

Membrane fusion And the Alphavirus Life Cycle

Kielian, M., Jan 1 1995, In : Advances in Virus Research. 45, C, p. 113-151 39 p.

Research output: Contribution to journalArticle

110 Scopus citations

Mutations in the putative fusion peptide of Semliki Forest virus affect spike protein oligomerization and virus assembly

Duffus, W. A., Levy-Mintz, P., Klimjack, M. R. & Kielian, M., Apr 1995, In : Journal of virology. 69, 4, p. 2471-2479 9 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations
1994

Membrane and protein interactions of a soluble form of the Semliki Forest virus fusion protein

Klimjack, M. R., Jeffrey, S. & Kielian, M., Nov 1 1994, In : Journal of virology. 68, 11, p. 6940-6946 7 p.

Research output: Contribution to journalArticle

81 Scopus citations
1993

Cholesterol is required in the exit pathway of Semliki Forest virus

Marquardt, M. T., Phalen, T. & Kielian, M., Oct 1993, In : Journal of Cell Biology. 123, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Role of spike protein conformational changes in fusion of Semliki Forest virus

Justman, J., Klimjack, M. R. & Kielian, M., Jan 1 1993, In : Journal of virology. 67, 12, p. 7597-7607 11 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations
1991

Cholesterol is required for infection by Semliki Forest virus

Phalen, T. & Kielian, M., Feb 1991, In : Journal of Cell Biology. 112, 4, p. 615-623 9 p.

Research output: Contribution to journalArticle

Open Access
137 Scopus citations

Mutagenesis of the putative fusion domain of the semliki forest virus spike protein

Levy-Mintz, P. & Kielian, M., Jan 1 1991, In : Journal of virology. 65, 8, p. 4292-4300 9 p.

Research output: Contribution to journalArticle

103 Scopus citations

Processing of the p62 envelope precursor protein of semliki forest virus

Jain, S. K., DeCandido, S. & Kielian, M., Oct 22 1991, In : Journal of Biological Chemistry. 266, 9, p. 5756-5761 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
1990

Biosynthesis, maturation, and acid activation of the Semliki Forest virus fusion protein

Kielian, M., Jungerwirth, S., Ullrich Sayad, K. & DeCandido, S., Jan 1 1990, In : Journal of virology. 64, 10, p. 4614-4624 11 p.

Research output: Contribution to journalArticle

66 Scopus citations
1989

Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants

Schmid, S., Fuchs, R., Kielian, M., Helenius, A. & Mellman, I., Jan 1 1989, In : Journal of Cell Biology. 108, 4, p. 1291-1300 10 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations
1986

[11] Assay of phagosome-lysosome fusion

Kielian, M., Jan 1 1986, In : Methods in enzymology. 132, C, p. 257-267 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus.

Kielian, M. C., Marsh, M. & Helenius, A., Dec 1 1986, In : EMBO Journal. 5, 12, p. 3103-3109 7 p.

Research output: Contribution to journalArticle

72 Scopus citations
1985

Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells

Helenius, A., Kielian, M., Wellsteed, J., Mellman, I. & Rudnick, G., Oct 23 1985, In : Journal of Biological Chemistry. 260, 9, p. 5691-5697 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

pH-induced alterations in the fusogenic spike protein of semliki forest virus

Kielian, M. & Helenius, A., Dec 1 1985, In : Journal of Cell Biology. 101, 6, p. 2284-2291 8 p.

Research output: Contribution to journalArticle

Open Access
122 Scopus citations
1984

Membrane fusion mutants of Semliki Forest virus

Kielian, M. C., Keranen, S., Kaariainen, L. & Helenius, A., Jan 1 1984, In : Journal of Cell Biology. 98, 1, p. 139-145 7 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Role of cholesterol in fusion of Semliki Forest virus with membranes

Kielian, M. C. & Helenius, A., Jan 1 1984, In : Journal of virology. 52, 1, p. 281-283 3 p.

Research output: Contribution to journalArticle

140 Scopus citations

Semliki forest virus entry and the endocytic pathway

Marsh, M., Kielian, M. C. & Helenius, A., Jan 1 1984, In : Biochemical Society transactions. 12, 6, p. 981-983 3 p.

Research output: Contribution to journalArticle

20 Scopus citations
1983

Membrane fusion proteins of enveloped animal viruses

White, J., Kielian, M. & Arihelenius, A., May 1983, In : Quarterly Reviews of Biophysics. 16, 2, p. 151-195 45 p.

Research output: Contribution to journalArticle

409 Scopus citations
1982

Intralysosomal accumulation of polyanions. I. Fusion of pinocytic and phagocytic vacuoles with secondary lysosomes

Kielian, M. C., Steinman, R. M. & Cohn, Z. A., Jun 1 1982, In : Journal of Cell Biology. 93, 3, p. 866-874 9 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
Open Access
40 Scopus citations
1981

Modulation of phagosome-lysosome fusion in mouse macrophages

Kielian, M. C. & Cohn, Z. A., Jan 1 1981, In : Journal of Experimental Medicine. 153, 4, p. 1015-1020 6 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Phorbol myristate acetate stimulates phagosome-lysosome fusion in mouse macrophages

Kielian, M. C. & Cohn, Z. A., Jul 1 1981, In : Journal of Experimental Medicine. 154, 1, p. 101-111 11 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
1980

Phagosome-lysosome fusion: Characterization of intracellular membrane fusion in mouse macrophages

Kielian, M. C. & Cohn, Z. A., Jun 1 1980, In : Journal of Cell Biology. 85, 3, p. 754-765 12 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations
1979

Characterization of phagosome-lysosome fusion in mouse macrophages

Kielian, M. C. & Cohn, Z. A., Jan 1 1979, In : Journal of Cell Biology. 83, 2 II, p. No. LP1306

Research output: Contribution to journalArticle

1977

Cell-cell interactions in blast transformation of rat lymphocytes by neuraminidase and galactose oxidase

Kielian, M. C., Beyer, C. F. & Bowers, W. E., Oct 1 1977, In : Experimental Cell Research. 109, 1, p. 211-221 11 p.

Research output: Contribution to journalArticle

5 Scopus citations