• 5286 Citations
  • 43 h-Index
1977 …2023
If you made any changes in Pure, your changes will be visible here soon.

Publications 1977 2019

  • 5286 Citations
  • 43 h-Index
  • 107 Article
  • 2 Review article
  • 1 Foreword/postscript
  • 1 Short survey
2019

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins

Quiroz, J. A., Malonis, R. J., Thackray, L. B., Cohen, C. A., Pallesen, J., Jangra, R. K., Brown, R. S., Hofmann, D., Holtsberg, F. W., Shulenin, S., Nyakatura, E. K., Durnell, L. A., Rayannavar, V., Daily, J. P., Ward, A. B., Aman, M. J., Dye, J. M., Chandran, K., Diamond, M. S., Kielian, M. & 1 others, Lai, J. R., Nov 1 2019, In : PLoS pathogens. 15, 11, p. e1008061

Research output: Contribution to journalArticle

Open Access
Chikungunya virus
Epitopes
Glycoproteins
Monoclonal Antibodies
Dominican Republic

Mechanism of Tetherin Inhibition of Alphavirus Release

Wan, J. J., Ooi, Y. S. & Kielian, M., Apr 1 2019, In : Journal of virology. 93, 7

Research output: Contribution to journalArticle

Alphavirus
endocytosis
Endocytosis
Protein Isoforms
viruses
3 Citations (Scopus)

Surface (S) Layer Proteins of Lactobacillus acidophilus Block Virus Infection via DC-SIGN Interaction

Acosta, M. P., Geoghegan, E. M., Lepenies, B., Ruzal, S., Kielian, M. & Martinez, M. G., Jan 1 2019, In : Frontiers in Microbiology. 10, MAR, 810.

Research output: Contribution to journalArticle

Open Access
Lactobacillus acidophilus
Virus Diseases
Alphavirus
Virus Attachment
Flavivirus

The alphavirus E2 membrane-proximal domain impacts capsid interaction and glycoprotein lattice formation

Byrd, E. A. & Kielian, M., Feb 1 2019, In : Journal of Virology. 93, 4, e0188118.

Research output: Contribution to journalArticle

Alphavirus
capsid
Capsid
Capsid Proteins
coat proteins

Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018

Badolo, A., Burt, F., Daniel, S., Fearns, R., Gudo, E. S., Kielian, M., Lescar, J., Shi, Y., von Brunn, A., Weiss, S. R. & Hilgenfeld, R., Feb 1 2019, In : Antiviral Research. 162, p. 142-150 9 p.

Research output: Contribution to journalReview article

Mozambique
Flavivirus
Viruses
Lassa virus
Crimean-Congo hemorrhagic fever virus
2018
5 Citations (Scopus)

Engineered dengue virus domain III proteins elicit cross-neutralizing antibody responses in mice

Frei, J. C., Wirchnianski, A. S., Govero, J., Vergnolle, O. M., Dowd, K. A., Pierson, T. C., Kielian, M., Girvin, M. E., Diamond, M. S. & Lai, J. R., Sep 1 2018, In : Journal of Virology. 92, 18, e01023.

Research output: Contribution to journalArticle

Dengue virus
Dengue Virus
Neutralizing Antibodies
neutralizing antibodies
Antibody Formation
2 Citations (Scopus)

Insertion of Dengue E into lipid bilayers studied by neutron reflectivity and molecular dynamics simulations

Vanegas, J. M., Heinrich, F., Rogers, D. M., Carson, B. D., La Bauve, S., Vernon, B. C., Akgun, B., Satija, S., Zheng, A., Kielian, M., Rempe, S. B. & Kent, M. S., May 1 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 5, p. 1216-1230 15 p.

Research output: Contribution to journalArticle

Lipid bilayers
Dengue
Neutrons
Lipid Bilayers
Molecular Dynamics Simulation

Preface to Volume 100: History and Looking Forward

Mettenleiter, T. C., Kielian, M. & Roossinck, M. J., Jan 1 2018, Advances in Virus Research. Academic Press Inc., p. xv-xxiv (Advances in Virus Research; vol. 100).

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

History
16 Citations (Scopus)

The alphavirus exit pathway: What we know and what we wish we knew

Brown, R. S., Wan, J. J. & Kielian, M., Feb 22 2018, In : Viruses. 10, 2, 89.

Research output: Contribution to journalReview article

Alphavirus
Chikungunya virus
Virus Release
Virus Assembly
RNA Viruses
2017
10 Citations (Scopus)

An alphavirus E2 membrane-proximal domain promotes envelope protein lateral interactions and virus budding

Byrd, E. A. & Kielian, M., Nov 1 2017, In : mBio. 8, 6, e01564-17.

Research output: Contribution to journalArticle

Alphavirus
Virus Release
Histidine
Membranes
Viruses
2016
6 Citations (Scopus)

Calcium-Dependent Rubella Virus Fusion Occurs in Early Endosomes

Dubé, M., Etienne, L., Fels, M. & Kielian, M., 2016, In : Journal of Virology. 90, 14, p. 6303-6313 11 p.

Research output: Contribution to journalArticle

Rubella virus
endosomes
Endosomes
Calcium
calcium
9 Citations (Scopus)

Intercellular Extensions Are Induced by the Alphavirus Structural Proteins and Mediate Virus Transmission

Martinez, M. G. & Kielian, M., Dec 15 2016, In : PLoS Pathogens. 12, 12, e1006061.

Research output: Contribution to journalArticle

Alphavirus
Viral Structural Proteins
Viruses
Alphavirus Infections
Cell Membrane
1 Citation (Scopus)

Method for measuring the unbinding energy of strongly-bound membrane-associated proteins

La Bauve, E., Vernon, B. C., Ye, D., Rogers, D. M., Siegrist, C. M., Carson, B. D., Rempe, S. B., Zheng, A., Kielian, M., Shreve, A. P. & Kent, M. S., Nov 1 2016, In : Biochimica et Biophysica Acta - Biomembranes. 1858, 11, p. 2753-2762 10 p.

Research output: Contribution to journalArticle

Free energy
Membrane Proteins
Membrane Lipids
Liposomes
Monomers
8 Citations (Scopus)

Role of TSPAN9 in alphavirus entry and early endosomes

Stiles, K. M. & Kielian, M., May 1 2016, In : Journal of Virology. 90, 9, p. 4289-4297 9 p.

Research output: Contribution to journalArticle

Semliki Forest virus
Semliki forest virus
Alphavirus
endosomes
Endosomes
2015
4 Citations (Scopus)

An alphavirus temperature-sensitive capsid mutant reveals stages of nucleocapsid assembly

Zheng, Y. & Kielian, M., Oct 1 2015, In : Virology. 484, p. 412-420 9 p.

Research output: Contribution to journalArticle

Alphavirus
Nucleocapsid
Capsid
Capsid Proteins
Temperature
17 Citations (Scopus)

BST2/Tetherin inhibition of alphavirus exit

Ooi, Y. S., Dubé, M. & Kielian, M., Apr 22 2015, In : Viruses. 7, 4, p. 2147-2167 21 p.

Research output: Contribution to journalArticle

Alphavirus
Semliki forest virus
Protein Isoforms
Chikungunya virus
Rubella virus
11 Citations (Scopus)
Epitope Mapping
Dengue Virus
Neutralizing Antibodies
Bacteriophages
Epitopes
40 Citations (Scopus)

Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion

Kleinfelter, L. M., Jangra, R., Jae, L. T., Herbert, A. S., Mittler, E-M., Stiles, K. M., Wirchnianski, A. S., Kielian, M., Brummelkamp, T. R., Dye, J. M. & Chandran, K., Jun 30 2015, In : mBio. 6, 4, e00801-15.

Research output: Contribution to journalArticle

Hantavirus
Membrane Fusion
Haploidy
Cholesterol
Membranes

Imaging the Alphavirus Exit Pathway

Guadalupe Martinez, M., Snapp, E. L., Perumal, G. S., Macaluso, F. P. & Kielian, M., 2015, In : Microscopy and Microanalysis. 21, S3, p. 409-410 2 p.

Research output: Contribution to journalShort survey

Imaging techniques

Interactions involved in pH protection of the alphavirus fusion protein

Fields, W. & Kielian, M., Dec 1 2015, In : Virology. 486, p. 173-179 7 p.

Research output: Contribution to journalArticle

Alphavirus
Virus Internalization
Proteins
Secretory Pathway
Furin
2 Citations (Scopus)

Potent Antibody Protection against an Emerging Alphavirus Threat

Kielian, M. & Saphire, E. O., Nov 19 2015, In : Cell. 163, 5, p. 1053-1054 2 p.

Research output: Contribution to journalArticle

Alphavirus
Viruses
Chikungunya virus
Viral Structures
Antibodies
2014
23 Citations (Scopus)

A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins

Zheng, A., Yuan, F., Kleinfelter, L. M. & Kielian, M., May 20 2014, In : Nature Communications. 5, 3877.

Research output: Contribution to journalArticle

Viral Envelope Proteins
Dengue Virus
viruses
Viruses
envelopes
27 Citations (Scopus)

Imaging the alphavirus exit pathway

Martinez, M. G., Snapp, E. L., Perumal, G. S., Macaluso, F. P. & Kielian, M., 2014, In : Journal of Virology. 88, 12, p. 6922-6933 12 p.

Research output: Contribution to journalArticle

Alphavirus
Virus Release
plasma membrane
Cell Membrane
image analysis
46 Citations (Scopus)

Mechanisms of virus membrane fusion proteins

Kielian, M., Sep 29 2014, In : Annual Review of Virology. 1, 1, p. 171-189 19 p.

Research output: Contribution to journalArticle

Membrane Fusion Proteins
Viral Fusion Proteins
Virus Internalization
Viral Envelope Proteins
Viruses
18 Citations (Scopus)

Rubella Virus: First Calcium-Requiring Viral Fusion Protein

Dubé, M., Rey, F. A. & Kielian, M., Dec 1 2014, In : PLoS Pathogens. 10, 12

Research output: Contribution to journalArticle

Viral Fusion Proteins
Rubella virus
Calcium
Virus Diseases
Membrane Fusion
2013
13 Citations (Scopus)

A key interaction between the alphavirus envelope proteins responsible for initial dimer dissociation during fusion

Fields, W. & Kielian, M., Apr 2013, In : Journal of Virology. 87, 7, p. 3774-3781 8 p.

Research output: Contribution to journalArticle

Alphavirus
viruses
Viruses
Proteins
proteins
42 Citations (Scopus)

A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

Vigant, F., Lee, J., Hollmann, A., Tanner, L. B., Akyol Ataman, Z., Yun, T., Shui, G., Aguilar, H. C., Zhang, D., Meriwether, D., Roman-Sosa, G., Robinson, L. R., Juelich, T. L., Buczkowski, H., Chou, S., Castanho, M. A. R. B., Wolf, M. C., Smith, J. K., Banyard, A., Kielian, M. & 7 others, Reddy, S., Wenk, M. R., Selke, M., Santos, N. C., Freiberg, A. N., Jung, M. E. & Lee, B., Apr 2013, In : PLoS Pathogens. 9, 4, e1003297.

Research output: Contribution to journalArticle

Cell Fusion
Antiviral Agents
Viruses
Membranes
Phospholipids
10 Citations (Scopus)

Cross-inhibition of chikungunya virus fusion and infection by alphavirus E1 domain III proteins

Martín;, C. S. S., Nanda, S., Zheng, Y., Fields, W. & Kielian, M., Jul 2013, In : Journal of Virology. 87, 13, p. 7680-7687 8 p.

Research output: Contribution to journalArticle

Semliki Forest virus
Chikungunya virus
Semliki forest virus
Alphavirus
stems
77 Citations (Scopus)

Flaviviruses: Braking the entering

Pierson, T. C. & Kielian, M., Feb 2013, In : Current Opinion in Virology. 3, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

Flavivirus
Virus Internalization
Virion
Virus Attachment
Cell Fusion
46 Citations (Scopus)

Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry

Ooi, Y. S., Stiles, K. M., Liu, C. Y., Taylor, G. M. & Kielian, M., 2013, In : PLoS Pathogens. 9, 12, p. 1-10 10 p., e1003835.

Research output: Contribution to journalArticle

Alphavirus
Alphavirus Infections
RNA Interference
Chikungunya virus
Genome
14 Citations (Scopus)

Imaging of the alphavirus capsid protein during virus replication

Zheng, Y. & Kielian, M., 2013, In : Journal of Virology. 87, 17, p. 9579-9589 11 p.

Research output: Contribution to journalArticle

Alphavirus
Capsid Proteins
Virus Replication
virus replication
coat proteins
23 Citations (Scopus)

The role of E3 in pH protection during alphavirus assembly and exit

Uchime, O., Fields, W. & Kielian, M., 2013, In : Journal of Virology. 87, 18, p. 10255-10262 8 p.

Research output: Contribution to journalArticle

Alphavirus
Secretory Pathway
Virus Internalization
viruses
Viruses
2012
3 Citations (Scopus)

Identification of a specific region in the E1 fusion protein involved in zinc inhibition of semliki forest virus fusion

Liu, C. Y. & Kielian, M., Apr 2012, In : Journal of Virology. 86, 7, p. 3588-3594 7 p.

Research output: Contribution to journalArticle

Semliki Forest virus
Semliki forest virus
Zinc
zinc
Alphavirus
2011
5 Citations (Scopus)

Alphavirus entry: NRAMP leads the way

Stiles, K. M. & Kielian, M., Aug 18 2011, In : Cell Host and Microbe. 10, 2, p. 92-93 2 p.

Research output: Contribution to journalArticle

Alphavirus
RNA Interference
Drosophila
Insects
Iron
16 Citations (Scopus)

The domain I-domain III linker plays an important role in the fusogenic conformational change of the alphavirus membrane fusion protein

Zheng, Y., Martín, C. S. S., Qin, Z. L. & Kielian, M., Jul 2011, In : Journal of Virology. 85, 13, p. 6334-6342 9 p.

Research output: Contribution to journalArticle

Membrane Fusion Proteins
Alphavirus
Membrane Fusion
Semliki Forest virus
Semliki forest virus
9 Citations (Scopus)

The interaction of alphavirus E1 protein with exogenous domain III defines stages in virus-membrane fusion

Roman-Sosa, G. & Kielian, M., Dec 2011, In : Journal of Virology. 85, 23, p. 12271-12279 9 p.

Research output: Contribution to journalArticle

Semliki Forest virus
Semliki forest virus
Alphavirus
Virus Internalization
Membrane Fusion
2010
69 Citations (Scopus)

Alphavirus entry and membrane fusion

Kielian, M., Chanel-Vos, C. & Liao, M., Apr 2010, In : Viruses. 2, 4, p. 796-825 30 p.

Research output: Contribution to journalArticle

Alphavirus
Membrane Fusion
Membrane Fusion Proteins
Viruses
Flavivirus
47 Citations (Scopus)

In Vitro and In vivo studies identify important features of dengue virus pr-E protein interactions

Zheng, A., Umashankar, M. & Kielian, M., Oct 2010, In : PLoS Pathogens. 6, 10, e1001157.

Research output: Contribution to journalArticle

Dengue Virus
Flavivirus
Viruses
Secretory Pathway
Proteins
33 Citations (Scopus)

In Vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein

Liao, M., Sánchez-San Martín, C., Zheng, A. & Kielian, M., Jun 2010, In : Journal of Virology. 84, 11, p. 5730-5740 11 p.

Research output: Contribution to journalArticle

Membrane Fusion Proteins
Viral Fusion Proteins
Virus Internalization
Dengue virus
Dengue Virus
8 Citations (Scopus)

Pseudorevertants of a semliki forest virus fusion-blocking mutation reveal a critical interchain interaction in the core trimer

Liu, C. Y., Besanceney, C., Song, Y. & Kielian, M., Nov 2010, In : Journal of Virology. 84, 22, p. 11624-11633 10 p.

Research output: Contribution to journalArticle

Semliki Forest virus
Semliki forest virus
Alphavirus
mutation
threonine
17 Citations (Scopus)

Structural biology: An alphavirus puzzle solved

Kielian, M., Dec 2 2010, In : Nature. 468, 7324, p. 645-646 2 p.

Research output: Contribution to journalArticle

Quaternary Protein Structure
cell organelle
Protein Multimerization
Chikungunya virus
Viral Fusion Proteins
2009
73 Citations (Scopus)

Dealing with low pH: entry and exit of alphaviruses and flaviviruses

Martín, C. S. S., Liu, C. Y. & Kielian, M., Nov 2009, In : Trends in Microbiology. 17, 11, p. 514-521 8 p.

Research output: Contribution to journalArticle

Alphavirus
Flavivirus
Viruses
Viral Matrix Proteins
Chikungunya virus
20 Citations (Scopus)

E1 mutants identify a critical region in the trimer interface of the Semliki Forest virus fusion protein

Liu, C. Y. & Kielian, M., Nov 2009, In : Journal of Virology. 83, 21, p. 11298-11306 9 p.

Research output: Contribution to journalArticle

viral fusion proteins
Semliki Forest virus
Viral Fusion Proteins
Semliki forest virus
Alphavirus
52 Citations (Scopus)

Role of conserved histidine residues in the low-pH dependence of the Semliki Forest virus fusion protein

Qin, Z. L., Zheng, Y. & Kielian, M., May 2009, In : Journal of Virology. 83, 9, p. 4670-4677 8 p.

Research output: Contribution to journalArticle

viral fusion proteins
Semliki Forest virus
Viral Fusion Proteins
Semliki forest virus
histidine
2008
32 Citations (Scopus)

A Stable Prefusion Intermediate of the Alphavirus Fusion Protein Reveals Critical Features of Class II Membrane Fusion

Sánchez-San Martín, C., Sosa, H. J. & Kielian, M., Dec 11 2008, In : Cell Host and Microbe. 4, 6, p. 600-608 9 p.

Research output: Contribution to journalArticle

Alphavirus
Membrane Fusion
Membranes
Proteins
Viral Fusion Proteins
64 Citations (Scopus)

Differential cholesterol binding by class II fusion proteins determines membrane fusion properties

Umashankar, M., Sánchez-San Martín, C., Liao, M., Reilly, B., Guo, A. Q., Taylor, G. & Kielian, M., Sep 2008, In : Journal of Virology. 82, 18, p. 9245-9253 9 p.

Research output: Contribution to journalArticle

Membrane Fusion Proteins
Cholesterol
cholesterol
Semliki Forest virus
Semliki forest virus
2007
8 Citations (Scopus)

Fusion induced by a class II viral fusion protein, Semliki Forest virus E1, is dependent on the voltage of the target cell

Markosyan, R. M., Kielian, M. & Cohen, F. S., Oct 2007, In : Journal of Virology. 81, 20, p. 11218-11225 8 p.

Research output: Contribution to journalArticle

viral fusion proteins
Semliki Forest virus
Viral Fusion Proteins
Semliki forest virus
capacitance
58 Citations (Scopus)

Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding

Taylor, G. M., Hanson, P. I. & Kielian, M., Dec 2007, In : Journal of Virology. 81, 24, p. 13631-13639 9 p.

Research output: Contribution to journalArticle

Rhabdoviridae
Alphavirus
Multivesicular Bodies
Vesiculovirus
Vesicular Stomatitis
2006
135 Citations (Scopus)

Class II virus membrane fusion proteins

Kielian, M., Jan 5 2006, In : Virology. 344, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

Membrane Fusion Proteins
Viral Fusion Proteins
Virus Internalization
Viruses
Cell Membrane
22 Citations (Scopus)

Functions of the stem region of the Semliki Forest virus fusion protein during virus fusion and assembly

Liao, M. & Kielian, M., Nov 2006, In : Journal of Virology. 80, 22, p. 11362-11369 8 p.

Research output: Contribution to journalArticle

viral fusion proteins
Semliki Forest virus
Viral Fusion Proteins
Semliki forest virus
Virus Assembly