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  • 10 Similar Profiles
Drosophila Medicine & Life Sciences
Proteins Medicine & Life Sciences
Growth Medicine & Life Sciences
Genes Medicine & Life Sciences
Imaginal Discs Medicine & Life Sciences
Cyclin E Medicine & Life Sciences
Histone Demethylases Medicine & Life Sciences
S Phase Medicine & Life Sciences

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Grants 2015 2022

Activation of Endogenous Transposable Elements by Myc During Aging

Secombe, J.

National Institutes of Health

9/30/164/30/22

Project: Research projectResearch Project, High Priority, Short Term Project Award

DNA Transposable Elements
Diptera
Genome
Phenotype
Single-Cell Analysis

Distinct Modes of Gene Regulation by KDM5

Secombe, J.

National Institutes of Health

1/15/1512/31/19

Project: Research projectResearch Project

Intellectual Disability
Genes
Mutation
Proteins
Diptera

Publications 1998 2016

  • 844 Citations
  • 12 h-Index
  • 19 Article
  • 1 Chapter
2 Citations

Early programming of the oocyte epigenome temporally controls late prophase i transcription and chromatin remodelling

Navarro-Costa, P., McCarthy, A., Prudêncio, P., Greer, C., Guilgur, L. G., Becker, J. D., Secombe, J., Rangan, P. & Martinho, R. G. Aug 10 2016 In : Nature Communications. 7, 12331

Research output: Research - peer-reviewArticle

Prophase
Chromatin Assembly and Disassembly
Oocytes
Transcription
Gene expression
7 Citations

The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif

Liu, X. & Secombe, J. Jul 31 2015 (Accepted/In press) In : Cell Reports.

Research output: Research - peer-reviewArticle

Histone Demethylases
Chromatin
Gene Expression
Proteins
Gene expression
10 Citations

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

Liu, X., Greer, C. & Secombe, J. Oct 1 2014 In : PLoS Genetics. 10, 10

Research output: Research - peer-reviewArticle

oxidative stress
genes
Oxidative Stress
Genes
gene
11 Citations

Myc-Dependent Genome Instability and Lifespan in Drosophila

Greer, C., Lee, M., Westerhof, M., Milholland, B., Spokony, R., Vijg, J. & Secombe, J. Sep 6 2013 In : PLoS One. 8, 9, e74641

Research output: Research - peer-reviewArticle

Genomic Instability
Drosophila
Mutation
mutation
genome
4 Citations

Myc in stem cell behaviour: insights from Drosophila.

Quinn, L. M., Secombe, J. & Hime, G. R. 2013 In : Advances in Experimental Medicine and Biology. 786, p. 269-285 17 p.

Research output: Research - peer-reviewArticle

Drosophila
Stem Cells
Stem cells
myc Genes
Oncogene Proteins