• 17481 Citations
  • 65 h-Index
1977 …2020
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Phosphatidylinositol 3-Kinase Medicine & Life Sciences
1-Phosphatidylinositol 4-Kinase Medicine & Life Sciences
Insulin Medicine & Life Sciences
Insulin Receptor Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Phosphatidylinositols Chemical Compounds
Phosphotransferases Chemical Compounds
Phosphorylation Chemical Compounds

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Grants 1977 2020

Phosphatidylinositol 3-Kinases
Breast Neoplasms
Neoplasm Metastasis
G-Protein-Coupled Receptors
Neoplasms

Motility and Invasion

Bresnick, A. R., Pollard, J. W., Stanley, E. R., Segall, J. E., Backer, J. M., Condeelis, J. S. & Pollard, J. W.

National Institutes of Health

6/1/035/31/19

Project: Research project

Neoplasms
Neoplasm Metastasis
Macrophages
Breast Neoplasms
Chemotaxis

LIVER RESEARCH CORE CENTER

Wolkoff, A. W., Reid, L., Krauter, K., Shafritz, D., Roy-Chowdhury, J., Rogler, C. E., Stanley, P., Snapp, E. L., Satir, B., Backer, J., Horwitz, S., Goldfischer, S., Roy-Chowdhury, J., Satir, P., Satir, P., Czaja, M. J., Gupta, S., Gupta, S., Meier, U. T., Davidson, A., Backer, J. M., Hays, R., Rogler, L., Roy-Chowdhury, J., Rogler, C., Backer, J. M., Rogler, C. E., Meier, U. T., Davidson, A., Hays, R., Rogler, L., Roy-Chowdhury, J., Rogler, C. & Meier, U. T.

National Institutes of Health

6/1/895/31/19

Project: Research project

Liver
Research Personnel
Research
Genetic Therapy
Organized Financing

Imaging VEGFR-1 in early metastatic lesions

Backer, J. M.

3/9/172/28/19

Project: Research project

Publications 1979 2019

A single discrete Rab5-binding site in phosphoinositide 3-kinase is required for tumor cell invasion

Heitz, S. D., Hamelin, D. J., Hoffmann, R. M., Greenberg, N., Salloum, G., Erami, Z., Khalil, B. D., Shymanets, A., Steidle, E. A., Gong, G. Q., Nürnberg, B., Burke, J. E., Flanagan, J. U., Bresnick, A. R. & Backer, J. M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 12, p. 4621-4633 13 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Tumors
Phosphotransferases
Binding Sites

PI3Kβ-A Versatile Transducer for GPCR, RTK, and Small GTPase Signaling

Bresnick, A. R. & Backer, J. M., Mar 1 2019, In : Endocrinology. 160, 3, p. 536-555 20 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Monomeric GTP-Binding Proteins
Receptor Protein-Tyrosine Kinases
G-Protein-Coupled Receptors
Transducers

Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis

Norwood Toro, L. E., Wang, Y., Condeelis, J. S., Jones, J. G., Backer, J. M. & Bresnick, A. R., Jan 1 2018, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
Myosin Heavy Chains
Phosphorylation
Neoplasm Metastasis
Neoplasms

S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms

Dulianinova, N., Ruiz, P. D., Gamble, M. J., Backer, J. M. & Bresnicka, A. R., Mar 1 2018, In : Molecular Biology of the Cell. 29, 5, p. 632-642 11 p.

Research output: Contribution to journalArticle

Myosins
Macrophages
Nonmuscle Myosin Type IIA
Chemotaxis
Acetylation
4 Citations (Scopus)

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Erami, Z., Khalil, B. D., Salloum, G., Yao, Y., LoPiccolo, J., Shymanets, A., Nürnberg, B., Bresnick, A. R. & Backer, J. M., Dec 1 2017, In : Biochemical Journal. 474, 23, p. 3903-3914 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Chemical activation
G-Protein-Coupled Receptors
Cells
1-Phosphatidylinositol 4-Kinase