• 16869 Citations
  • 64 h-Index
1977 …2020
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  • 7 Similar Profiles
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
1-Phosphatidylinositol 4-Kinase Medicine & Life Sciences
Insulin Medicine & Life Sciences
Insulin Receptor Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Phosphatidylinositols Chemical Compounds
Phosphotransferases Chemical Compounds
Phosphorylation Chemical Compounds

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Grants 1977 2020

Fluorescent Nanodiamonds for Multiplexed Imaging and Diagnostics

Backer, J. M.

8/20/187/31/19

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

color
diamonds
color centers
marking
cancer

Imaging VEGFR-1 in early metastatic lesions

Backer, J. M.

3/9/172/28/19

Project: Research projectExploratory/Developmental Grants

Vascular Endothelial Growth Factor Receptor-1
Hematopoietic Stem Cells
Neoplasm Metastasis
Breast Neoplasms
Click Chemistry
Phosphatidylinositol 3-Kinases
Breast Neoplasms
Neoplasm Metastasis
G-Protein-Coupled Receptors
Neoplasms

Motility and Invasion

Bresnick, A. R., Pollard, J. W., Stanley, E. R., Segall, J. E., Backer, J. M., Condeelis, J. S. & Pollard, J. W.

National Institutes of Health

6/1/035/31/19

Project: Research projectResearch Program Projects

Neoplasms
Neoplasm Metastasis
Macrophages
Breast Neoplasms
Chemotaxis

LIVER RESEARCH CORE CENTER

Wolkoff, A. W., Reid, L., Krauter, K., Shafritz, D., Roy-Chowdhury, J., Rogler, C. E., Stanley, P., Snapp, E. L., Satir, B., Backer, J., Horwitz, S., Goldfischer, S., Roy-Chowdhury, J., Satir, P., Satir, P., Czaja, M. J., Gupta, S., Gupta, S., Meier, U. T., Davidson, A., Backer, J. M., Hays, R., Rogler, L., Roy-Chowdhury, J., Rogler, C., Backer, J. M., Rogler, C. E., Meier, U. T., Davidson, A., Hays, R., Rogler, L., Roy-Chowdhury, J. & Rogler, C.

National Institutes of Health

6/1/895/31/19

Project: Research projectCenter Core Grants

Liver
Research Personnel
Research
Genetic Therapy
Medicine

Publications 1979 2018

  • 16869 Citations
  • 64 h-Index
  • 150 Article
  • 1 Chapter
  • 1 Editorial
  • 1 Review article

Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis

Norwood Toro, L. E., Wang, Y., Condeelis, J. S., Jones, J. G., Backer, J. M. & Bresnick, A. R., Jan 1 2018, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
Myosin Heavy Chains
Phosphorylation
Neoplasm Metastasis
Neoplasms

S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms

Dulyaninova, N. G., Ruiz, P. D., Gamble, M. J., Backer, J. M. & Bresnicka, A. R., Mar 1 2018, In : Molecular Biology of the Cell. 29, 5, p. 632-642 11 p.

Research output: Contribution to journalArticle

Myosins
Macrophages
Nonmuscle Myosin Type IIA
Chemotaxis
Acetylation
2 Citations

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Erami, Z., Khalil, B. D., Salloum, G., Yao, Y., LoPiccolo, J., Shymanets, A., Nürnberg, B., Bresnick, A. R. & Backer, J. M., Dec 1 2017, In : Biochemical Journal. 474, 23, p. 3903-3914 12 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Chemical activation
1-Phosphatidylinositol 4-Kinase
Cells
G-Protein-Coupled Receptor Kinases
8 Citations

Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells

Houslay, D. M., Anderson, K. E., Chessa, T., Kulkarni, S., Fritsch, R., Downward, J., Backer, J. M., Stephens, L. R. & Hawkins, P. T., Aug 16 2016, In : Science Signaling. 9, 441, ra82.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Receptor Protein-Tyrosine Kinases
Myeloid Cells
Phosphatidylinositols
Macrophage Colony-Stimulating Factor
9 Citations

GPCR signaling mediates tumor metastasis via PI3Kβ

Khalil, B. D., Hsueh, C., Cao, Y., Saab, W. F. A., Wang, Y., Condeelis, J. S., Bresnick, A. R. & Backer, J. M., May 15 2016, In : Cancer Research. 76, 10, p. 2944-2953 10 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Phosphatidylinositol 3-Kinases
Neoplasm Metastasis
Neoplasms
Receptor Protein-Tyrosine Kinases