• 18026 Citations
  • 66 h-Index
1977 …2020
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Jonathan M. Backer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Phosphatidylinositol 3-Kinase Medicine & Life Sciences
1-Phosphatidylinositol 4-Kinase Medicine & Life Sciences
Insulin Medicine & Life Sciences
Insulin Receptor Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Phosphatidylinositols Chemical Compounds
Phosphotransferases Chemical Compounds
Phosphorylation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 1977 2020

Phosphatidylinositol 3-Kinases
Breast Neoplasms
Neoplasm Metastasis
G-Protein-Coupled Receptors
Neoplasms

Imaging VEGFR-1 in early metastatic lesions

Backer, J. M.

3/9/172/28/19

Project: Research project

Targeted drug delivery to tumor microenvironment

Backer, J. M.

3/20/154/19/16

Project: Research project

Publications 1979 2019

2 Citations (Scopus)

A single discrete Rab5-binding site in phosphoinositide 3-kinase is required for tumor cell invasion

Heitz, S. D., Hamelin, D. J., Hoffmann, R. M., Greenberg, N., Salloum, G., Erami, Z., Khalil, B. D., Shymanets, A., Steidle, E. A., Gong, G. Q., Nürnberg, B., Burke, J. E., Flanagan, J. U., Bresnick, A. R. & Backer, J. M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 12, p. 4621-4633 13 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Tumors
Phosphotransferases
Binding Sites
4 Citations (Scopus)

PI3Kβ-A Versatile Transducer for GPCR, RTK, and Small GTPase Signaling

Bresnick, A. R. & Backer, J. M., Mar 1 2019, In : Endocrinology. 160, 3, p. 536-555 20 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Monomeric GTP-Binding Proteins
Receptor Protein-Tyrosine Kinases
G-Protein-Coupled Receptors
Transducers

PI3Kβ is selectively required for growth factor-stimulated macropinocytosis

Salloum, G., Jakubik, C. T., Erami, Z., Heitz, S. D., Bresnick, A. R. & Backer, J. M., Aug 16 2019, In : Journal of cell science. 132, 16

Research output: Contribution to journalArticle

Open Access
1-Phosphatidylinositol 4-Kinase
Intercellular Signaling Peptides and Proteins
Neoplasms
Clathrin
Receptor Protein-Tyrosine Kinases

PI3Kβ links integrin activation and PI(3,4)P2 production during invadopodial maturation

Erami, Z., Heitz, S., Bresnick, A. R. & Backer, J. M., Aug 15 2019, In : Molecular biology of the cell. 30, 18, p. 2367-2376 10 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylinositol 3-Kinases
Integrins
phosphoinositide 5-phosphatase
Breast Neoplasms
Neoplasms
2 Citations (Scopus)

Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis

Norwood Toro, L. E., Wang, Y., Condeelis, J. S., Jones, J. G., Backer, J. M. & Bresnick, A. R., Jan 1 2018, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Nonmuscle Myosin Type IIA
Myosin Heavy Chains
Phosphorylation
Neoplasm Metastasis
Neoplasms