No photo of Hernando J. Sosa

View Scopus Profile

Hernando J. Sosa, Ph.D.

  • 1494 Citations
  • 21 h-Index
1986 …2023
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Hernando J. Sosa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Kinesin Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Tubulin Medicine & Life Sciences
X-Ray Diffraction Medicine & Life Sciences
Polarization Microscopy Medicine & Life Sciences
Fluorescence Polarization Medicine & Life Sciences
Fluorescence Microscopy Medicine & Life Sciences
Myosins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2002 2023

MECHANISM OF MICROTUBULE DYNAMICS REGULATION BY KINESINS

Sosa, H. J.

National Institutes of Health

3/1/15 → 1/31/23

Project: Research project

Kinesin
Microtubules
Tubulin
Polymers
Centrioles

Phosphoregulation of the Kinesin Motor Domain: Structure, Dynamics and Function

Sosa, H. J., Ma, A. O., Ma, A. O., Sharp, D. J. & Gerfen, G. J.

National Institutes of Health

5/1/12 → 4/30/16

Project: Research project

Kinesin
Phosphorylation
Microtubules
Catalytic Domain
Hydrolysis

STRUCTURAL BASIS OF KINESIN MOTOR MOVEMENT

Sosa, H. J.

National Institutes of Health

7/1/02 → 6/30/07

Project: Research project

Kinesin
Microtubules
Adenosine Triphosphate
Hydrolysis
Hand

Structural Basis of Kinesin Motor Movement

Sosa, H. J.

National Institutes of Health

7/1/02 → 8/31/14

Project: Research project

Kinesin
Microtubules
Walkers
Catalytic Domain
Neoplasms

Publications 1986 2019

  • 1494 Citations
  • 21 h-Index
  • 30 Article
  • 1 Book
  • 1 Chapter
  • 1 Comment/debate

Kinesin-5 Promotes Microtubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin

Chen, G. Y., Cleary, J. M., Asenjo, A. B., Chen, Y., Mascaro, J. A., Arginteanu, D. F. J., Sosa, H. J. & Hancock, W. O., Jul 22 2019, In : Current Biology. 29, 14, p. 2259-2269.e4

Research output: Contribution to journal › Article

Kinesin
kinesin
Tubulin
tubulin
Microtubules

Correction: Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13sd (Nature Communications DOI: 10.1038/s41467-018-04044-8)

Benoit, M. P. M. H., Asenjo, A. B. & Sosa, H. J., Dec 1 2018, In : Nature Communications. 9, 1, 2748.

Research output: Contribution to journal › Comment/debate

depolymerization
Kinesin
Depolymerization
Microtubules
communication
7 Citations (Scopus)

Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s

Benoit, M. P. M. H., Asenjo, A. B. & Sosa, H. J., Dec 1 2018, In : Nature Communications. 9, 1, 1662.

Research output: Contribution to journal › Article

depolymerization
Kinesin
Depolymerization
Microtubules
nucleotides
1 Citation (Scopus)

Use of single molecule fluorescence polarization microscopy to study protein conformation and dynamics of kinesin–microtubule complexes

Benoit, M. P. M. H. & Sosa, H. J., 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1665. p. 199-216 18 p. (Methods in Molecular Biology; vol. 1665).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Polarization Microscopy
Protein Conformation
Fluorescence Polarization
Fluorescence Microscopy
Cytoskeletal Proteins
5 Citations (Scopus)

Distinct Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule

Chatterjee, C., Benoit, M. P. M. H., DePaoli, V., Diaz-Valencia, J. D., Asenjo, A. B., Gerfen, G. J., Sharp, D. J. & Sosa, H. J., Apr 12 2016, In : Biophysical Journal. 110, 7, p. 1593-1604 12 p.

Research output: Contribution to journal › Article

Kinesin
Microtubules
Neck
Polarization Microscopy
Microtubule Proteins