• 713 Citations
  • 8 h-Index

Research output per year

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  • 713 Citations
  • 8 h-Index
  • 12 Article
  • 1 Short survey
  • 1 Review article

Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models

Vyhlídalová, B., Bartoňková, I., Jiskrová, E., Li, H., Mani, S. & Dvořák, Z., May 15 2020, In : Toxicology Letters. 324, p. 104-110 7 p.

Research output: Contribution to journalArticle

  • Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs

    Li, H., Ranhotra, H. S., Mani, S., Dvořák, Z., Sokol, H. & Müller, R., 2020, (Accepted/In press) In : Drug Discovery Today.

    Research output: Contribution to journalShort survey

  • Targeting the pregnane X receptor using microbial metabolite mimicry

    Dvořák, Z., Kopp, F., Costello, C. M., Kemp, J. S., Li, H., Vrzalová, A., Štěpánková, M., Bartoňková, I., Jiskrová, E., Poulíková, K., Vyhlídalová, B., Nordstroem, L. U., Karunaratne, C. V., Ranhotra, H. S., Mun, K. S., Naren, A. P., Murray, I. A., Perdew, G. H., Brtko, J., Toporova, L. & 22 others, Schön, A., Wallace, W. G., Walton, W. G., Redinbo, M. R., Sun, K., Beck, A., Kortagere, S., Neary, M. C., Chandran, A., Vishveshwara, S., Cavalluzzi, M. M., Lentini, G., Cui, J. Y., Gu, H., March, J. C., Chatterjee, S., Matson, A., Wright, D., Flannigan, K. L., Hirota, S. A., Sartor, R. B. & Mani, S., Apr 7 2020, In : EMBO Molecular Medicine. 12, 4, e11621.

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations

    Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens

    Ervin, S. M., Li, H., Lim, L., Roberts, L. R., Liang, X., Mani, S. & Redinbo, M. R., Dec 6 2019, In : Journal of Biological Chemistry. 294, 49, p. 18586-18599 14 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity

    Pasquel, D., Doricakova, A., Li, H., Kortagere, S., Krasowski, M. D., Biswas, A., Walton, W. G., Redinbo, M. R., Dvorak, Z. & Mani, S., Sep 1 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 9, p. 1155-1169 15 p.

    Research output: Contribution to journalArticle

  • 7 Scopus citations