• 11613 Citations
  • 29 h-Index
20002020

Research output per year

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Publications

2011

Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-Π2 and NF-ΰB

Purkayastha, S., Zhang, G. & Cai, D., Jul 2011, In : Nature Medicine. 17, 7, p. 883-887 5 p.

Research output: Contribution to journalArticle

161 Scopus citations
2009

NFκB-mediated metabolic inflammation in peripheral tissues versus central nervous system

Cai, D., Aug 15 2009, In : Cell Cycle. 8, 16, p. 2542-2548 7 p.

Research output: Contribution to journalReview article

Open Access
63 Scopus citations
2008

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

Zhang, X., Zhang, G., Zhang, H., Karin, M., Bai, H. & Cai, D., Oct 3 2008, In : Cell. 135, 1, p. 61-73 13 p.

Research output: Contribution to journalArticle

865 Scopus citations

Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes

Goldfine, A. B., Silver, R., Aldhahi, W., Cai, D., Tatro, E., Lee, J. & Shoelson, S. E., Jan 1 2008, In : Clinical and Translational Science. 1, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

194 Scopus citations
2005

Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

Cai, D., Yuan, M., Frantz, D. F., Melendez, P. A., Hansen, L., Lee, J. & Shoelson, S. E., Feb 1 2005, In : Nature Medicine. 11, 2, p. 183-190 8 p.

Research output: Contribution to journalArticle

1564 Scopus citations

Regulation of IκB kinase and NF-κB in contracting adult rat skeletal muscle

Ho, R. C., Hirshman, M. F., Li, Y., Cai, D., Farmer, J. R., Aschenbach, W. G., Witczak, C. A., Shoelson, S. E. & Goodyear, L. J., Oct 1 2005, In : American Journal of Physiology - Cell Physiology. 289, 4 58-4, p. C794-C801

Research output: Contribution to journalArticle

93 Scopus citations
2004

IKKβ/NF-κB activation causes severe muscle wasting in mice

Cai, D., Frantz, J. D., Tawa, N. E., Melendez, P. A., Oh, B. C., Lidov, H. G. W., Hasselgren, P. O., Frontera, W. R., Lee, J., Glass, D. J. & Shoelson, S. E., Oct 15 2004, In : Cell. 119, 2, p. 285-298 14 p.

Research output: Contribution to journalArticle

912 Scopus citations
2003

Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5

Cai, D., Dhe-Paganon, S., Melendez, P. A., Lee, J. & Shoelson, S. E., Jul 11 2003, In : Journal of Biological Chemistry. 278, 28, p. 25323-25330 8 p.

Research output: Contribution to journalArticle

136 Scopus citations
2001
2000
17 Scopus citations