• 39548 Citations
  • 93 h-Index
1978 …2023
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Fingerprint Dive into the research topics where Ana Maria Cuervo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Autophagy Medicine & Life Sciences
Lysosomes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Lysosome-Associated Membrane Glycoproteins Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Degradation Chemical Compounds
Quality Control Medicine & Life Sciences
Aging of materials Chemical Compounds

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Grants 1978 2023

Cystinosis
Lysosomal Storage Diseases
Autophagy
Cystine
Cysteamine
Frontotemporal Dementia
Autophagy
Clustered Regularly Interspaced Short Palindromic Repeats
Neurons
tau Proteins
Autophagy
Alzheimer Disease
Brain
Homeostasis
Proteins
Autophagy
Hepatocytes
Endocytosis
Liver
Personnel Selection
Shock
Research Personnel
Research
Rodentia
Homeostasis

Publications 1990 2019

3 Citations (Scopus)

A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy

Hernandez, I., Luna, G., Rauch, J. N., Reis, S. A., Giroux, M., Karch, C. M., Boctor, D., Sibih, Y. E., Storm, N. J., Diaz, A., Kaushik, S., Zekanowski, C., Kang, A. A., Hinman, C. R., Cerovac, V., Guzman, E., Zhou, H., Haggarty, S. J., Goate, A. M., Fisher, S. K. & 2 others, Cuervo, A. M. & Kosik, K. S., Jan 1 2019, In : Science Translational Medicine. 11, 485

Research output: Contribution to journalArticle

Tauopathies
Farnesyltranstransferase
Lysosomes
Pathology
Brain

Age- And stress-associated C. Elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response

Butler, V. J., Gao, F., Corrales, C. I., Cortopassi, W. A., Caballero, B., Vohra, M., Ashrafi, K., Cuervo, A. M., Jacobson, M. P., Coppola, G. & Kao, A. W., Jan 1 2019, In : PLoS genetics. 15, 8, e1008295.

Research output: Contribution to journalArticle

Open Access
Caenorhabditis elegans
homeostasis
protein
proteinases
neurodegenerative diseases
1 Citation (Scopus)

Analysis of chaperone-mediated autophagy

Juste, Y. R. & Cuervo, A. M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 703-727 25 p. (Methods in Molecular Biology; vol. 1880).

Research output: Chapter in Book/Report/Conference proceedingChapter

Autophagy
Proteins
Lysosomes
Recycling
Lipid Metabolism

Chaperone-mediated autophagy upregulation rescues megalin expression and localization in cystinotic proximal tubule cells

Zhang, J., He, J., Johnson, J. L., Rahman, F., Gavathiotis, E., Cuervo, A. M. & Catz, S. D., Jan 1 2019, In : Frontiers in Endocrinology. 10, 00021.

Research output: Contribution to journalArticle

Open Access
Low Density Lipoprotein Receptor-Related Protein-2
Autophagy
Up-Regulation
Factor IX
Cystinosis
1 Citation (Scopus)

Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy

Valdor, R., García-Bernal, D., Riquelme, D., Martinez, C. M., Moraleda, J. M., Cuervo, A. M., Macian, F. & Martinez, S., Oct 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20655-20665 11 p.

Research output: Contribution to journalArticle

Open Access
Pericytes
Autophagy
Glioblastoma
Up-Regulation
Neoplasms