Medicine

Projects

Projects per year 1975 2024

• 34 Not started
• 141 Active
• 717 Finished

Projects per year

Search results

• Active

  HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic study

  Yotebieng, M.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  4/15/21 → 3/31/22

  Project: Research project

  • Low Birth Weight Infant 100%
  • HIV 89%
  • Mortality 36%
  • Child 32%
  • Therapeutics 15%

• Molecular Mechanism of Brown Adipose Tissue Regression

  Feng, D. & Pessin, J. E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 2/28/22

  Project: Research project

  • Brown Adipocytes 100%
  • Pyroptosis 74%
  • Brown Adipose Tissue 68%
  • Receptor Protein-Tyrosine Kinases 30%
  • Knockout Mice 25%

• Molecular Mechanism of Brown Adipose Tissue Regression

  Feng, D. & Pessin, J. E.

  4/15/21 → 2/28/22

  Project: Research project

  • Brown Adipocytes 100%
  • Pyroptosis 74%
  • Brown Adipose Tissue 51%
  • Receptor Protein-Tyrosine Kinases 30%
  • Knockout Mice 25%

• Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities

  Johns, T. S.

  4/15/21 → 12/31/21

  Project: Research project

  • Chronic Renal Insufficiency 100%
  • Research Personnel 43%
  • Kidney 41%
  • Mentors 38%
  • Inflammation 36%

• Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities

  Johns, T. S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 12/31/21

  Project: Research project

  • Chronic Renal Insufficiency 100%
  • Inflammation 50%
  • Kidney 50%
  • Diet 48%
  • Research Personnel 43%

• HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic study

  Yotebieng, M.

  4/15/21 → 3/31/22

  Project: Research project

  • HIV 100%
  • Low Birth Weight Infant 68%
  • Microbiota 15%
  • Inflammation 14%
  • Pregnant Women 13%

• Contribution of macrophages in the HSC niche

  Frenette, P. S.

  National Heart, Lung, and Blood Institute

  4/1/21 → 2/28/22

  Project: Research project

  • Stem Cell Niche 100%
  • Macrophages 91%
  • Hematopoietic Stem Cells 88%
  • Bone Marrow 74%
  • Regeneration 21%

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  4/1/21 → 3/31/22

  Project: Research project

  • Gait 100%
  • Dementia 51%
  • Cognitive Dysfunction 50%
  • Brain 34%
  • Social Networking 29%

• Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants Living

  Akiyama, M. J.

  4/1/21 → 3/31/22

  Project: Research project

  • Hepacivirus 100%
  • Criminal Law 38%
  • Mentors 22%
  • Risk-Taking 18%
  • HIV 12%

• Contribution of macrophages in the HSC niche

  Frenette, P. S.

  4/1/21 → 2/28/22

  Project: Research project

  • Macrophages 100%
  • Bone Marrow 78%
  • Hematopoietic Stem Cells 53%
  • Stem Cell Niche 34%
  • Regeneration 22%

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  4/1/21 → 3/31/22

  Project: Research project

  • Cardiac Myocytes 100%
  • Pressure 69%
  • Fibroblasts 59%
  • Heart 52%
  • Macrophages 47%

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  2/1/21 → 1/31/22

  Project: Research project

  • HIV 100%
  • Internet-Based Intervention 14%
  • HIV Infections 9%
  • India 9%
  • Epidemics 9%

• The impact of HIV on accelerated aging in the female genital tract: a pilot trial of topical estradiol to improve the vaginal microbiome and symptoms of vaginal atrophy in menopausal women with HIV

  Murphy, K. J.

  2/1/21 → 1/31/22

  Project: Research project

  • HIV 100%
  • Female Genitalia 57%
  • Dysbiosis 51%
  • Microbiota 47%
  • Inflammation 24%

• Cardiac Calcification and Cholesterol Efflux in Older Adults

  Bortnick, A. E.

  2/1/21 → 1/31/22

  Project: Research project

  • Cholesterol 100%
  • Calcification of Aortic Valve 72%
  • Parents 37%
  • Longevity 33%
  • Coronary Vessels 30%

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  2/1/21 → 1/31/22

  Project: Research project

  • Smooth Muscle Myocytes 100%
  • Vascular Remodeling 73%
  • Electron Transport Complex I 56%
  • Embryonic Development 28%
  • Vascular Diseases 20%

• Exhaled small RNA biomarkers to detect and monitor airway disease

  Loudig, O. D. & Spivack, S. D.

  National Heart, Lung, and Blood Institute

  1/1/21 → 12/31/21

  Project: Research project

  • Biomarkers 100%
  • Exosomes 96%
  • Chronic Obstructive Pulmonary Disease 91%
  • RNA 86%
  • Asthma 80%

• Exhaled small RNA biomarkers to detect and monitor airway disease

  Loudig, O. D. & Spivack, S. D.

  1/1/21 → 12/31/21

  Project: Research project

  • Biomarkers 100%
  • Exosomes 90%
  • Chronic Obstructive Pulmonary Disease 85%
  • Asthma 74%
  • High-Throughput Nucleotide Sequencing 73%

• The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosis

  Chan, J.

  1/1/21 → 12/31/21

  Project: Research project

  • phosphatidylinositol mannoside 100%
  • Mycobacterium tuberculosis 86%
  • Cell Wall 26%
  • Tuberculosis 21%
  • Growth 21%

• Beta Cell Intracellular Calcium and Diabetes

  Santulli, G.

  12/1/20 → 11/30/21

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Autophagy 48%
  • Mitophagy 45%
  • Insulin Secretion 33%
  • Endoplasmic Reticulum 31%

• Utility of Centrally Acting Angiotensin Converting Enzyme Inhibitors to slow the progression of Dementia

  George, C. J.

  9/15/20 → 5/31/22

  Project: Research project

  • Cognitive Dysfunction 100%
  • Angiotensin-Converting Enzyme Inhibitors 85%
  • Gait 66%
  • Retirement 41%
  • Organized Financing 41%

• Th2A cells mediate outcomes of aspirin-exacerbated respiratory disease

  Jerschow, E.

  9/3/20 → 8/31/21

  Project: Research project

  • Aspirin 100%
  • Th2 Cells 66%
  • Prostaglandin D2 62%
  • Nasal Polyps 30%
  • prostaglandin R2 D-isomerase 14%

• Einstein/Rwanda/DRC Consortium for Research in HIV/HPV/Malignancies

  Adedimeji, A. A., Anastos, K. & Anastos, K.

  9/1/20 → 8/31/21

  Project: Research project

  • Rwanda 100%
  • Democratic Republic of the Congo 42%
  • Military 24%
  • grant 14%
  • productivity 14%

• Role of HCAR1 in glucose homeostasis

  Jo, Y.

  8/15/20 → 8/31/21

  Project: Research project

  • brown adipose tissue 100%
  • receptors 57%
  • acids 37%
  • lactates 35%
  • glucose 32%

• AIF1/Iba1 in microglial function and stroke

  Sibinga, N. E. S.

  7/1/20 → 6/30/22

  Project: Research project

  • Stroke 100%
  • Microglia 89%
  • Wounds and Injuries 42%
  • Inflammation Mediators 18%
  • Cell Lineage 15%

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  National Institute on Aging

  6/15/20 → 3/31/22

  Project: Research project

  • Gait 100%
  • Dementia 69%
  • Cognitive Dysfunction 67%
  • Brain 42%
  • Social Networking 30%

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  National Heart, Lung, and Blood Institute

  4/3/20 → 3/31/22

  Project: Research project

  • Cardiac Myocytes 100%
  • Pressure 69%
  • Heart 61%
  • Fibroblasts 59%
  • Transforming Growth Factor beta 55%

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  National Institute of Mental Health

  3/1/20 → 1/31/22

  Project: Research project

  • HIV 100%
  • Technology 50%
  • Therapeutics 14%
  • Internet-Based Intervention 14%
  • HIV Infections 9%

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  3/1/20 → 1/31/22

  Project: Research project

  • Vascular Remodeling 100%
  • Smooth Muscle Myocytes 96%
  • Electron Transport Complex I 54%
  • Embryonic Development 27%
  • Vascular Diseases 19%

• Cardiac Calcification and Cholesterol Efflux in Older Adults

  Bortnick, A. E.

  National Heart, Lung, and Blood Institute

  2/15/20 → 1/31/22

  Project: Research project

  • Cholesterol 100%
  • Calcification of Aortic Valve 76%
  • Parents 38%
  • Longevity 34%
  • Coronary Vessels 31%

• The impact of HIV on accelerated aging in the female genital tract: a pilot trial of topical estradiol to improve the vaginal microbiome and symptoms of vaginal atrophy in menopausal women with HIV

  Murphy, K. J.

  National Institute on Aging

  2/1/20 → 1/31/22

  Project: Research project

  • Female Genitalia 100%
  • HIV 86%
  • Microbiota 82%
  • Atrophy 65%
  • Estradiol 60%

• The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosis

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  1/16/20 → 12/31/21

  Project: Research project

  • phosphatidylinositol mannoside 100%
  • Mycobacterium tuberculosis 86%
  • Tuberculosis 47%
  • Cell Wall 26%
  • Growth 21%

• Novel effectors of insulin action in the liver

  Yang, F.

  1/3/20 → 11/30/23

  Project: Research project

  • ST 679 100%
  • Mediator Complex 58%
  • Liver 46%
  • Insulin Resistance 41%
  • Sterol Regulatory Element Binding Protein 1 34%

• Beta Cell Intracellular Calcium and Diabetes

  Santulli, G.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/1/20 → 11/30/21

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Calcium 76%
  • Autophagy 48%
  • Mitophagy 45%
  • Insulin Secretion 33%

• Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting

  Brust, J. C. M.

  12/26/19 → 11/30/24

  Project: Research project

  • bedaquiline 100%
  • Clofazimine 63%
  • Multidrug-Resistant Tuberculosis 23%
  • Extensively Drug-Resistant Tuberculosis 11%
  • HIV 10%

• Molecular regulation of gut lipid metabolism by mTOR and autophagy proteins

  Singh, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/17/19 → 8/31/21

  Project: Research project

  • Autophagy 100%
  • Triglycerides 98%
  • TOR Serine-Threonine Kinases 75%
  • Lipid Metabolism 64%
  • Endoplasmic Reticulum 52%

• Circadian Mechanisms of Diabetes Prevention in Aged mice

  Singh, R.

  National Institute on Aging

  9/15/19 → 5/31/22

  Project: Research project

  • Autophagy 100%
  • Gluconeogenesis 68%
  • Caloric Restriction 47%
  • Type 2 Diabetes Mellitus 28%
  • lysosomal proteins 27%

• Circadian Mechanisms of Diabetes Prevention in Aged mice

  Singh, R.

  9/15/19 → 5/31/22

  Project: Research project

  • Autophagy 100%
  • Gluconeogenesis 68%
  • Caloric Restriction 47%
  • Type 2 Diabetes Mellitus 28%
  • lysosomal proteins 27%

• Hyptothalamic autophagy and metabolic regulation in aging

  Singh, R.

  8/1/19 → 3/31/24

  Project: Research project

  • Macroautophagy 100%
  • Autophagy 85%
  • Pro-Opiomelanocortin 43%
  • Hypertriglyceridemia 38%
  • Triglycerides 33%

• Antibodies, B cells and resistance to human cryptococcosis

  Pirofski, L.

  National Institute of Allergy and Infectious Diseases

  7/25/19 → 6/30/22

  Project: Research project

  • Cryptococcal Meningitis 100%
  • Cryptococcosis 49%
  • Immune Reconstitution Inflammatory Syndrome 41%
  • B-Lymphocytes 34%
  • Glucans 31%

• Antibodies, B cells and resistance to human cryptococcosis

  Pirofski, L.

  7/25/19 → 6/30/22

  Project: Research project

  • Cryptococcal Meningitis 100%
  • Immune Reconstitution Inflammatory Syndrome 41%
  • Glucans 31%
  • HIV 26%
  • B-Lymphocytes 14%

• Cellular mechanisms by which Neisseria gonorrhoeae infects the female reproductive tract

  Stein, D. T.

  7/5/19 → 6/30/23

  Project: Research project

  • Sexually Transmitted Diseases 100%
  • Infections 78%
  • Cervix Uteri 50%
  • opacity proteins 47%
  • Epithelial Cells 45%

• Characteristics and protective efficacy of human antibodies against M. tuberculosis

  Achkar, J. M.

  7/1/19 → 6/30/22

  Project: Research project

  • Tuberculosis 100%
  • Mycobacterium tuberculosis 71%
  • Polysaccharides 45%
  • Tuberculosis Vaccines 34%
  • Epitopes 20%

• Characteristics and protective efficacy of human antibodies against M. tuberculosis

  Achkar, J. M.

  National Institute of Allergy and Infectious Diseases

  7/1/19 → 6/30/22

  Project: Research project

  • Tuberculosis 100%
  • Mycobacterium tuberculosis 74%
  • Polysaccharides 48%
  • Antibodies 43%
  • Tuberculosis Vaccines 36%

• Somatotropic Signaling and Resilience to Aging and Alzheimer's Disease

  Milman, S.

  National Institute on Aging

  4/15/19 → 1/31/22

  Project: Research project

  • Alzheimer Disease 100%
  • Aged, 80 and over 47%
  • Pandemics 45%
  • Dementia 37%
  • SARS Virus 31%

• Cognitive and Emotional Resilience to the COVID-19 pandemic among older adults at risk for Alzheimer's disease

  Milman, S.

  4/15/19 → 1/31/22

  Project: Research project

  • SARS Virus 100%
  • Pandemics 57%
  • Dementia 56%
  • Social Support 52%
  • Cognitive Dysfunction 44%

• Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53

  Zhao, H. & Schwartz, E. L.

  4/12/19 → 3/31/22

  Project: Research project

  • Small Cell Lung Carcinoma 100%
  • Drug Therapy 17%
  • Heterografts 16%
  • Ubiquitination 13%
  • Neoplasms 11%

• Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53

  Zhao, H. & Schwartz, E. L.

  National Cancer Institute

  4/12/19 → 3/31/22

  Project: Research project

  • Small Cell Lung Carcinoma 100%
  • Drug Therapy 18%
  • Heterografts 16%
  • Ubiquitination 13%
  • Neoplasms 12%

• IgM in the regulation of TB immunity

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  2/15/19 → 1/31/22

  Project: Research project

  • Mycobacterium tuberculosis 100%
  • Immunoglobulin M 94%
  • Germinal Center 74%
  • Immunity 52%
  • Humoral Immunity 24%

• IgM in the regulation of TB immunity

  Chan, J.

  2/15/19 → 1/31/22

  Project: Research project

  • Mycobacterium tuberculosis 100%
  • Immunoglobulin M 98%
  • Germinal Center 74%
  • Humoral Immunity 24%
  • B-Lymphocytes 24%

• Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory Support

  Saeed, O.

  National Heart, Lung, and Blood Institute

  1/15/19 → 12/31/21

  Project: Research project

  • Hemolysis 100%
  • Platelet Activation 91%
  • Platelet Aggregation 55%
  • Thrombosis 36%
  • Sildenafil Citrate 29%