Medicine

Projects

Projects per year 1975 2024

• 21 Not started
• 87 Active
• 443 Finished

Projects per year

Search results

• Active

  Molecular Mechanism of Brown Adipose Tissue Regression

  Feng, D. & Pessin, J. E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 2/28/22

  Project: Research project

  • Brown Adipocytes 100%
  • Pyroptosis 74%
  • Brown Adipose Tissue 68%
  • Receptor Protein-Tyrosine Kinases 30%
  • Knockout Mice 25%

• HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic study

  Yotebieng, M.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  4/15/21 → 3/31/22

  Project: Research project

  • Low Birth Weight Infant 100%
  • HIV 89%
  • Mortality 36%
  • Child 32%
  • Therapeutics 15%

• Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities

  Johns, T. S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 12/31/21

  Project: Research project

  • Chronic Renal Insufficiency 100%
  • Inflammation 50%
  • Kidney 50%
  • Diet 48%
  • Research Personnel 43%

• Contribution of macrophages in the HSC niche

  Frenette, P. S.

  National Heart, Lung, and Blood Institute

  4/1/21 → 2/28/22

  Project: Research project

  • Stem Cell Niche 100%
  • Macrophages 91%
  • Hematopoietic Stem Cells 88%
  • Bone Marrow 74%
  • Regeneration 21%

• Exhaled small RNA biomarkers to detect and monitor airway disease

  Loudig, O. D. & Spivack, S. D.

  National Heart, Lung, and Blood Institute

  1/1/21 → 12/31/21

  Project: Research project

  • Biomarkers 100%
  • Exosomes 96%
  • Chronic Obstructive Pulmonary Disease 91%
  • RNA 86%
  • Asthma 80%

• Utility of Centrally Acting Angiotensin Converting Enzyme Inhibitors to slow the progression of Dementia

  George, C. J.

  9/15/20 → 5/31/22

  Project: Research project

  • Cognitive Dysfunction 100%
  • Angiotensin-Converting Enzyme Inhibitors 85%
  • Gait 66%
  • Retirement 41%
  • Organized Financing 41%

• Th2A cells mediate outcomes of aspirin-exacerbated respiratory disease

  Jerschow, E.

  9/3/20 → 8/31/21

  Project: Research project

  • Aspirin 100%
  • Th2 Cells 66%
  • Prostaglandin D2 62%
  • Nasal Polyps 30%
  • prostaglandin R2 D-isomerase 14%

• Einstein/Rwanda/DRC Consortium for Research in HIV/HPV/Malignancies

  Adedimeji, A. A., Anastos, K. & Anastos, K.

  9/1/20 → 8/31/21

  Project: Research project

  • Rwanda 100%
  • Democratic Republic of the Congo 42%
  • Military 24%
  • grant 14%
  • productivity 14%

• Role of HCAR1 in glucose homeostasis

  Jo, Y.

  8/15/20 → 8/31/21

  Project: Research project

  • brown adipose tissue 100%
  • receptors 57%
  • acids 37%
  • lactates 35%
  • glucose 32%

• AIF1/Iba1 in microglial function and stroke

  Sibinga, N. E. S.

  7/1/20 → 6/30/22

  Project: Research project

  • Stroke 100%
  • Microglia 89%
  • Wounds and Injuries 42%
  • Inflammation Mediators 18%
  • Cell Lineage 15%

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  National Institute on Aging

  6/15/20 → 3/31/22

  Project: Research project

  • Gait 100%
  • Dementia 69%
  • Cognitive Dysfunction 67%
  • Brain 42%
  • Social Networking 30%

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  National Heart, Lung, and Blood Institute

  4/3/20 → 3/31/22

  Project: Research project

  • Cardiac Myocytes 100%
  • Pressure 69%
  • Heart 61%
  • Fibroblasts 59%
  • Transforming Growth Factor beta 55%

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  3/1/20 → 1/31/22

  Project: Research project

  • Vascular Remodeling 100%
  • Smooth Muscle Myocytes 96%
  • Electron Transport Complex I 54%
  • Embryonic Development 27%
  • Vascular Diseases 19%

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  National Institute of Mental Health

  3/1/20 → 1/31/22

  Project: Research project

  • HIV 100%
  • Technology 50%
  • Therapeutics 14%
  • Internet-Based Intervention 14%
  • HIV Infections 9%

• Cardiac Calcification and Cholesterol Efflux in Older Adults

  Bortnick, A. E.

  National Heart, Lung, and Blood Institute

  2/15/20 → 1/31/22

  Project: Research project

  • Cholesterol 100%
  • Calcification of Aortic Valve 76%
  • Parents 38%
  • Longevity 34%
  • Coronary Vessels 31%

• The impact of HIV on accelerated aging in the female genital tract: a pilot trial of topical estradiol to improve the vaginal microbiome and symptoms of vaginal atrophy in menopausal women with HIV

  Murphy, K. J.

  National Institute on Aging

  2/1/20 → 1/31/22

  Project: Research project

  • Female Genitalia 100%
  • HIV 86%
  • Microbiota 82%
  • Atrophy 65%
  • Estradiol 60%

• The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosis

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  1/16/20 → 12/31/21

  Project: Research project

  • phosphatidylinositol mannoside 100%
  • Mycobacterium tuberculosis 86%
  • Tuberculosis 47%
  • Cell Wall 26%
  • Growth 21%

• Novel effectors of insulin action in the liver

  Yang, F.

  1/3/20 → 11/30/23

  Project: Research project

  • ST 679 100%
  • Mediator Complex 58%
  • Liver 46%
  • Insulin Resistance 41%
  • Sterol Regulatory Element Binding Protein 1 34%

• Beta Cell Intracellular Calcium and Diabetes

  Santulli, G.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/1/20 → 11/30/21

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Calcium 76%
  • Autophagy 48%
  • Mitophagy 45%
  • Insulin Secretion 33%

• Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting

  Brust, J. C. M.

  12/26/19 → 11/30/24

  Project: Research project

  • bedaquiline 100%
  • Clofazimine 63%
  • Multidrug-Resistant Tuberculosis 23%
  • Extensively Drug-Resistant Tuberculosis 11%
  • HIV 10%

• Molecular regulation of gut lipid metabolism by mTOR and autophagy proteins

  Singh, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/17/19 → 8/31/21

  Project: Research project

  • Autophagy 100%
  • Triglycerides 98%
  • TOR Serine-Threonine Kinases 75%
  • Lipid Metabolism 64%
  • Endoplasmic Reticulum 52%

• Cellular mechanisms by which Neisseria gonorrhoeae infects the female reproductive tract

  Stein, D. T.

  7/5/19 → 6/30/23

  Project: Research project

  • Sexually Transmitted Diseases 100%
  • Infections 78%
  • Cervix Uteri 50%
  • opacity proteins 47%
  • Epithelial Cells 45%

• Somatotropic Signaling and Resilience to Aging and Alzheimer's Disease

  Milman, S.

  National Institute on Aging

  4/15/19 → 1/31/22

  Project: Research project

  • Alzheimer Disease 100%
  • Aged, 80 and over 47%
  • Pandemics 45%
  • Dementia 37%
  • SARS Virus 31%

• Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53

  Zhao, H. & Schwartz, E. L.

  National Cancer Institute

  4/12/19 → 3/31/22

  Project: Research project

  • Small Cell Lung Carcinoma 100%
  • Drug Therapy 18%
  • Heterografts 16%
  • Ubiquitination 13%
  • Neoplasms 12%

• IgM in the regulation of TB immunity

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  2/15/19 → 1/31/22

  Project: Research project

  • Mycobacterium tuberculosis 100%
  • Immunoglobulin M 94%
  • Germinal Center 74%
  • Immunity 52%
  • Humoral Immunity 24%

• Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory Support

  Saeed, O.

  National Heart, Lung, and Blood Institute

  1/15/19 → 12/31/21

  Project: Research project

  • Hemolysis 100%
  • Platelet Activation 91%
  • Platelet Aggregation 55%
  • Thrombosis 36%
  • Sildenafil Citrate 29%

• Developmental PBDE exposure, gut microbiome, and diabetes

  Mani, S.

  National Institute of Environmental Health Sciences

  1/1/19 → 12/31/21

  Project: Research project

  • Halogenated Diphenyl Ethers 100%
  • Gastrointestinal Microbiome 53%
  • Dysbiosis 31%
  • Indoles 27%
  • Tryptophan 27%

• Integrative, age-related changes in genome and epigenome in human lung in relation to smoking

  Vijg, J. & Spivack, S. D.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/21

  Project: Research project

  • Epigenome 100%
  • DNA Damage 58%
  • Smoking 58%
  • Genome 54%
  • Lung 50%

• Mechanisms of cardiovascular disease

  Kitsis, R. N. & Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/21

  Project: Research project

  • Cardiovascular Diseases 100%
  • Molecular Biology 51%
  • Cardiologists 35%
  • Vascular Diseases 30%
  • Myocardial Ischemia 28%

• The Center of Excellence in Promoting LHS Operations and Research at Einstein/Montefiore (EXPLORE)

  Cunningham, C. O., Marantz, P. R. & Rinke, M. L.

  9/30/18 → 9/29/23

  Project: Research project

  • infrastructure 100%
  • health 97%
  • health care 51%
  • resources 46%
  • leader 45%

• Social Dancing Intervention for older adults at high risk of Alzheimer's disease and other dementias: A pilot study

  Blumen, H. M., Verghese, J. & Verghese, J.

  National Institute on Aging

  9/15/18 → 8/31/21

  Project: Research project

  • Dementia 100%
  • Executive Function 80%
  • Alzheimer Disease 71%
  • Neuronal Plasticity 37%
  • Cognitive Dysfunction 31%

• Peer mentorship to improve outcomes in patients on maintenance hemodialysis

  Melamed, M. L., Golestaneh, L., Golestaneh, L. & Melamed, M. L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/6/18 → 7/31/21

  Project: Research project

  • Mentors 100%
  • Renal Dialysis 63%
  • Maintenance 47%
  • Dialysis 46%
  • Self-Management 33%

• Optimizing smoking cessation interventions for PLWH in Nairobi, Kenya

  Shuter, J. & Shuter, J.

  National Cancer Institute

  9/5/18 → 8/31/21

  Project: Research project

  • Kenya 100%
  • Acquired Immunodeficiency Syndrome 91%
  • Smoking Cessation 90%
  • Methadone 76%
  • HIV 75%

• Identification and targeting of pathways separating healthy stem cell aging from malignant transformation

  Will, B.

  National Cancer Institute

  9/1/18 → 8/31/21

  Project: Research project

  • Chaperone-Mediated Autophagy 100%
  • Cellular Senescence 50%
  • Stem Cells 41%
  • Hematopoietic Stem Cells 24%
  • Genetic Models 11%

• Identifying and Reducing Disparities in Outcomes Among Economically Vulnerable and Minority Young Adults with Type 1 Diabetes

  Agarwal, S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/1/18 → 8/31/21

  Project: Research project

  • Type 1 Diabetes Mellitus 100%
  • Young Adult 90%

• Assessing genome sequence integrity in normal human cells

  Spivack, S. D., Vijg, J. & Vijg, J.

  National Institute of Environmental Health Sciences

  8/15/18 → 5/31/22

  Project: Research project

  • Genome 100%
  • Mutation 91%
  • Smoke 47%
  • Tobacco 47%
  • DNA 41%

• Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer

  Mani, S.

  National Cancer Institute

  8/14/18 → 7/31/21

  Project: Research project

  • Pregnane 100%
  • Metabolite 38%
  • Indole 23%
  • Non Toxic 8%

• Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney Disease

  Chen, W.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/18 → 5/31/22

  Project: Research project

  • Vascular Calcification 100%
  • Dynamic Light Scattering 73%
  • Chronic Renal Insufficiency 56%
  • Osteocalcin 13%
  • Biomarkers 12%

• Apolipoprotein A5 and Gallstone Formation

  Wang, D. Q. H.

  7/20/18 → 4/30/22

  Project: Research project

  • apolipoproteins 100%
  • bile 58%
  • cholelithiasis 55%
  • cholesterol 30%
  • liver 26%

• Genetic and Dietary Interactions in MMR Deficient Colon Tumorigenesis

  Edelmann, W., Augenlicht, L. H. & Edelmann, W.

  National Cancer Institute

  7/5/18 → 5/31/22

  Project: Research project

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • Colon 97%
  • Carcinogenesis 91%
  • villin 59%
  • Stem Cells 34%

• Thiamine as a Renal Protective Agent in Septic Shock

  Moskowitz, A. L.

  National Institute of General Medical Sciences

  6/1/18 → 5/31/22

  Project: Research project

  • Renal Agents 100%
  • Thiamine 98%
  • Protective Agents 81%
  • Septic Shock 74%
  • Sepsis 31%

• Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosis

  Porcelli, S. A., Chan, J. & Porcelli, S. A.

  National Institute of Allergy and Infectious Diseases

  5/1/18 → 4/30/22

  Project: Research project

  • Indoleamine-Pyrrole 2,3,-Dioxygenase 100%
  • Tuberculosis 53%
  • Protein Isoforms 29%
  • Immunosuppressive Agents 21%
  • Kynurenine 20%

• Cognitive-Motor Interference Assessment for Improving Neurologic and Physical Disability Outcomes (CAMINANDO) in Survivors of Severe Acute Respiratory Failure

  Hope, A. A.

  National Heart, Lung, and Blood Institute

  3/1/18 → 2/28/22

  Project: Research project

  • Respiratory Insufficiency 100%
  • Survivors 72%
  • Nervous System 67%
  • Acute Lung Injury 67%
  • Mentors 55%

• Mechanisms regulating the aging of HSC niches

  Frenette, P. S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/15/18 → 12/31/21

  Project: Research project

  • Stem Cell Niche 100%
  • Sympathetic Nervous System 96%
  • Hematopoietic Stem Cells 85%
  • Nestin 35%
  • Bone Marrow 31%

• Developing and pilot testing an intervention to increase opioid tapering in primary care

  Perez, H. R.

  9/1/17 → 8/31/21

  Project: Research project

  • Opioid Analgesics 100%
  • Primary Health Care 76%
  • Pain 65%
  • Chronic Pain 29%
  • Retention in Care 23%

• Leveraging the electronic health record to reduce opioid analgesic prescriptions

  Bachhuber, M. A.

  8/15/17 → 7/31/22

  Project: Research project

  • Opioid Analgesics 100%
  • Prescriptions 41%
  • Electronic Health Records 28%
  • Implementation Science 10%
  • Research Personnel 9%

• Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants Living with Hepatitis C-The HCV-ACCELERATE Trial

  Akiyama, M. J.

  NATIONAL INSTITUTE ON DRUG ABUSE

  8/15/17 → 3/31/22

  Project: Research project

  • Hepacivirus 100%
  • Hepatitis C 67%
  • Criminal Law 37%
  • Mentors 22%
  • Risk-Taking 18%

• Minimizing losses from HIV care under universal treatment in Rwanda

  Ross, J.

  National Institute of Mental Health

  8/4/17 → 7/31/21

  Project: Research project

  • Rwanda 100%
  • HIV 51%
  • Therapeutics 13%
  • Africa South of the Sahara 11%
  • Health Services 9%

• Astrocytic Target Mechanisms in Obesity

  Yang, Y.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/17 → 7/31/21

  Project: Research project

  • Obesity 100%
  • Astrocytes 93%
  • Adenosine 62%
  • Agouti-Related Protein 60%
  • Diet 34%

• Buprenorphine treatment at syringe exchanges to reduce opioid misuse and HIV risk

  Fox, A. D.

  NATIONAL INSTITUTE ON DRUG ABUSE

  8/1/17 → 2/28/22

  Project: Research project

  • Buprenorphine 100%
  • Syringes 76%
  • Opioid Analgesics 66%
  • HIV 48%
  • Needle-Exchange Programs 39%