Medicine

Projects

Projects per year 1975 1989 2002 2005 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2021 2024

• 42 Not started
• 155 Active
• 822 Finished

Projects per year

Search results

• Not started

  Studies On A Calcium Sensing Receptor

  Spiegel, A. M., De Casper, A., Berndt, R. S. & Fine, J.

  Project: Research project

  • Calcium-Sensing Receptors 100%
  • Droseraceae 35%
  • Cysteine 26%
  • Disulfides 19%
  • Calcium 19%

• Structure/Function Of Men1 Gene And Its Protein Product

  Spiegel, A. M.

  National Institute on Deafness and Other Communication Disorders

  Project: Research project

  • neoplasms 100%
  • Drosophila 51%
  • genes 46%
  • mice 46%
  • proteins 38%

• HUMORAL HYPERCALCEMIA OF MALIGNANCY

  Spiegel, A. M.

  Project: Research project

  • Humoral Hypercalcemia Of Malignancy 100%
  • Hypercalcemia 68%
  • Leydig Cell Tumor 44%
  • Wells syndrome 42%
  • Inbred F344 Rats 34%

• STUDIES ON MCCUNE-ALBRIGHT SYNDROME

  Spiegel, A. M. & Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • somatic mutation 100%
  • mutants 62%
  • skin lesions 59%
  • mutation 59%
  • Cushing syndrome 51%

• MOLECULAR BIOLOGIC STUDIES ON THE CAUSE OF PARATHYROID NEOPLASIA

  Spiegel, A. M.

  Project: Research project

  • neoplasms 100%
  • parathyroid glands 42%
  • hyperparathyroidism 32%
  • oncogenes 24%
  • hyperplasia 21%

• STRUCTURE, SECRETION AND MECHANISM OF ACTION OF PARATHYROID HORMONE

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • parathyroid hormone 100%
  • mechanism of action 51%
  • secretion 37%
  • hormones 30%
  • developmental orthopedic disease 28%

• PSEUDOHYPOPARATHYROIDISM AND RELATED DISORDERS

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Pseudohypoparathyroidism 100%
  • Parathyroid Hormone 27%
  • Hormones 16%
  • Adenylyl Cyclases 12%
  • Albright's hereditary osteodystrophy 8%

• STUDIES ON MCCUNE-ALBRIGHT SYNDROME

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • somatic mutation 100%
  • mutation 68%
  • skin lesions 61%
  • hyperthyroidism 59%
  • Cushing syndrome 49%

• STRUCTURE AND FUNCTION OF THE MEN1 GENE AND ITS PROTEIN PRODUCT, MENIN

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • protein products 100%
  • tumor suppressor genes 60%
  • neoplasms 43%
  • genes 42%
  • somatic mutation 27%

• GUANINE NUCLEOTIDE BINDING PROTEINS AS RECEPTOR-EFFECTOR COUPLERS

  Spiegel, A. M.

  Project: Research project

  • Guanine Nucleotides 100%
  • Carrier Proteins 68%
  • G-protein Beta gamma 17%
  • Signal Transduction 13%
  • Potassium Channels 10%

• GUANINE NUCLEOTIDE BINDING PROTEINS AS RECEPTOR-EFFECTOR COUPLERS

  Spiegel, A. M.

  Project: Research project

  • GTP-Binding Proteins 100%
  • Guanine Nucleotides 49%
  • Carrier Proteins 34%
  • Transducin 29%
  • Rhodopsin 25%

• STUDIES ON NEPHROGENIC DIABETES INSIPIDUS

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • diabetes insipidus 100%
  • Nephrogenic Diabetes Insipidus 91%
  • Vasopressin Receptors 52%
  • vasopressin 40%
  • receptors 32%

• Structure/Function Of Men1 Gene And Its Protein Product

  Spiegel, A. M., Wackym, P. A., Morell, R., Dibello, P. & Wackym, P. A.

  Project: Research project

  • neoplasms 100%
  • Drosophila 55%
  • mice 47%
  • genes 45%
  • proteins 27%

• GUANINE NUCLEOTIDE BINDING PROTEINS AS RECEPTOR-EFFECTOR COUPLERS

  Spiegel, A. M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Guanine Nucleotides 100%
  • Carrier Proteins 68%
  • GTP-Binding Proteins 18%
  • Mutation 14%
  • Signal Transduction 14%
• Active

  Leveraging community health workers to improve SARS-CoV-2 testing and mitigation among criminal justice-involved individuals accessing a corrections-focused community-based organization

  Akiyama, M. J.

  9/21/21 → 5/31/22

  Project: Research project

  • health workers 100%
  • costs 69%
  • justice 65%
  • Criminal Justice 57%
  • organization 54%

• PI3 Kinase Inactivation in Myelodysplastic Syndrome

  Gritsman, K.

  9/17/21 → 8/31/22

  Project: Research project

  • Myelodysplastic Syndromes 100%
  • Hematopoietic Stem Cells 87%
  • Phosphatidylinositol 3-Kinases 73%
  • Autophagy 56%
  • Erythropoiesis 51%

• The Neuroimmunology of Depression in Women Living With HIV

  Gabbay, V. & Sharma, A.

  9/16/21 → 6/30/22

  Project: Research project

  • Reward 100%
  • HIV 95%
  • Depression 73%
  • Anhedonia 57%
  • Kynurenine 46%

• The Neural Underpinnings of Depression and Cannabis Use in Young PLWH

  Gabbay, V., Sharma, A. & Starrels, J. L.

  9/1/21 → 7/31/22

  Project: Research project

  • Reward 100%
  • Cannabis 80%
  • Habenula 57%
  • Pain 47%
  • Depression 40%

• Dronabinol for the reduction of chronic pain and inflammation in people with sickle cell disease

  Curtis, S.

  9/1/21 → 5/31/22

  Project: Research project

  • Sickle Cell Anemia 100%
  • Dronabinol 64%
  • Chronic Pain 53%
  • Cannabis 34%
  • Inflammation 23%

• Functional identification of vagal sensory neurons innervating the liver

  Jo, Y.

  9/1/21 → 8/31/22

  Project: Research project

  • Neurons 100%
  • Solitary Nucleus 99%
  • Liver 94%
  • Sensory Receptor Cells 86%
  • Appetite 63%

• Candida auris extracellular vesicles subvert host immune responses

  Nosanchuk, J. D.

  8/17/21 → 7/31/22

  Project: Research project

  • T-lymphocytes 100%
  • mycoses 31%
  • immunosuppressive agents 28%
  • cytokines 22%
  • immune response 20%

• Preserving physical function in patients with kidney disease

  Abramowitz, M. K.

  8/3/21 → 6/30/22

  Project: Research project

  • Fibrosis 100%
  • Chronic Renal Insufficiency 96%
  • Dialysis 89%
  • Muscles 81%
  • Skeletal Muscle 35%

• Modulation of Mitofusin Activity to Treat Heart Disease

  Kitsis, R. N.

  8/1/21 → 7/31/22

  Project: Research project

  • Heart Failure 100%
  • Cardiac Myocytes 90%
  • Myocardial Infarction 70%
  • Mitochondrial Dynamics 50%
  • Infarction 49%

• The impact of medical cannabis on pain and inflammation in people living with HIV

  Slawek, D. E.

  7/15/21 → 6/30/22

  Project: Research project

  • Medical Marijuana 100%
  • HIV 36%
  • Neuralgia 24%
  • Pain 13%
  • Cannabidiol 13%

• Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities

  Johns, T. S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 12/31/21

  Project: Research project

  • Chronic Renal Insufficiency 100%
  • Inflammation 50%
  • Kidney 50%
  • Diet 48%
  • Research Personnel 43%

• HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic study

  Yotebieng, M.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  4/15/21 → 3/31/22

  Project: Research project

  • Low Birth Weight Infant 100%
  • HIV 89%
  • Mortality 36%
  • Child 32%
  • Therapeutics 15%

• HIV/ART, low birth weight, and mortality in HIV-exposed uninfected children: a translational mechanistic study

  Yotebieng, M.

  4/15/21 → 3/31/22

  Project: Research project

  • HIV 100%
  • Low Birth Weight Infant 68%
  • Microbiota 15%
  • Inflammation 14%
  • Pregnant Women 13%

• Diet Related Inflammation and Kidney Function Decline in Racial/Ethnic Minorities

  Johns, T. S.

  4/15/21 → 12/31/21

  Project: Research project

  • Chronic Renal Insufficiency 100%
  • Research Personnel 43%
  • Kidney 41%
  • Mentors 38%
  • Inflammation 36%

• Molecular Mechanism of Brown Adipose Tissue Regression

  Feng, D. & Pessin, J. E.

  4/15/21 → 2/28/22

  Project: Research project

  • Brown Adipocytes 100%
  • Pyroptosis 74%
  • Brown Adipose Tissue 51%
  • Receptor Protein-Tyrosine Kinases 30%
  • Knockout Mice 25%

• Molecular Mechanism of Brown Adipose Tissue Regression

  Feng, D. & Pessin, J. E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/21 → 2/28/22

  Project: Research project

  • Brown Adipocytes 100%
  • Pyroptosis 74%
  • Brown Adipose Tissue 68%
  • Receptor Protein-Tyrosine Kinases 30%
  • Knockout Mice 25%

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  4/1/21 → 3/31/22

  Project: Research project

  • Cardiac Myocytes 100%
  • Pressure 69%
  • Fibroblasts 59%
  • Heart 52%
  • Macrophages 47%

• Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants Living

  Akiyama, M. J.

  4/1/21 → 3/31/22

  Project: Research project

  • Hepacivirus 100%
  • Criminal Law 38%
  • Mentors 22%
  • Risk-Taking 18%
  • HIV 12%

• Contribution of macrophages in the HSC niche

  Frenette, P. S.

  National Heart, Lung, and Blood Institute

  4/1/21 → 2/28/22

  Project: Research project

  • Stem Cell Niche 100%
  • Macrophages 91%
  • Hematopoietic Stem Cells 88%
  • Bone Marrow 74%
  • Regeneration 21%

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  4/1/21 → 3/31/22

  Project: Research project

  • Gait 100%
  • Dementia 51%
  • Cognitive Dysfunction 50%
  • Brain 34%
  • Social Networking 29%

• Contribution of macrophages in the HSC niche

  Frenette, P. S.

  4/1/21 → 2/28/22

  Project: Research project

  • Macrophages 100%
  • Bone Marrow 78%
  • Hematopoietic Stem Cells 53%
  • Stem Cell Niche 34%
  • Regeneration 22%

• The impact of HIV on accelerated aging in the female genital tract: a pilot trial of topical estradiol to improve the vaginal microbiome and symptoms of vaginal atrophy in menopausal women with HIV

  Murphy, K. J.

  2/1/21 → 1/31/22

  Project: Research project

  • HIV 100%
  • Female Genitalia 57%
  • Dysbiosis 51%
  • Microbiota 47%
  • Inflammation 24%

• Cardiac Calcification and Cholesterol Efflux in Older Adults

  Bortnick, A. E.

  2/1/21 → 1/31/22

  Project: Research project

  • Cholesterol 100%
  • Calcification of Aortic Valve 72%
  • Parents 37%
  • Longevity 33%
  • Coronary Vessels 30%

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  2/1/21 → 1/31/22

  Project: Research project

  • HIV 100%
  • Internet-Based Intervention 14%
  • HIV Infections 9%
  • India 9%
  • Epidemics 9%

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  2/1/21 → 1/31/22

  Project: Research project

  • Smooth Muscle Myocytes 100%
  • Vascular Remodeling 73%
  • Electron Transport Complex I 56%
  • Embryonic Development 28%
  • Vascular Diseases 20%

• Exhaled small RNA biomarkers to detect and monitor airway disease

  Loudig, O. D. & Spivack, S. D.

  1/1/21 → 12/31/21

  Project: Research project

  • Biomarkers 100%
  • Exosomes 90%
  • Chronic Obstructive Pulmonary Disease 85%
  • Asthma 74%
  • High-Throughput Nucleotide Sequencing 73%

• Exhaled small RNA biomarkers to detect and monitor airway disease

  Loudig, O. D. & Spivack, S. D.

  National Heart, Lung, and Blood Institute

  1/1/21 → 12/31/21

  Project: Research project

  • Biomarkers 100%
  • Exosomes 96%
  • Chronic Obstructive Pulmonary Disease 91%
  • RNA 86%
  • Asthma 80%

• The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosis

  Chan, J.

  1/1/21 → 12/31/21

  Project: Research project

  • phosphatidylinositol mannoside 100%
  • Mycobacterium tuberculosis 86%
  • Cell Wall 26%
  • Tuberculosis 21%
  • Growth 21%

• Beta Cell Intracellular Calcium and Diabetes

  Santulli, G.

  12/1/20 → 11/30/21

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Autophagy 48%
  • Mitophagy 45%
  • Insulin Secretion 33%
  • Endoplasmic Reticulum 31%

• Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting

  Brust, J. C. M.

  National Institute of Allergy and Infectious Diseases

  12/1/20 → 11/30/21

  Project: Research project

  • bedaquiline 100%
  • Clofazimine 63%
  • Multidrug-Resistant Tuberculosis 23%
  • Extensively Drug-Resistant Tuberculosis 11%
  • HIV 10%

• Utility of Centrally Acting Angiotensin Converting Enzyme Inhibitors to slow the progression of Dementia

  George, C. J.

  9/15/20 → 5/31/22

  Project: Research project

  • Cognitive Dysfunction 100%
  • Angiotensin-Converting Enzyme Inhibitors 85%
  • Gait 66%
  • Retirement 41%
  • Organized Financing 41%

• AIF1/Iba1 in microglial function and stroke

  Sibinga, N. E. S.

  7/1/20 → 6/30/22

  Project: Research project

  • Stroke 100%
  • Microglia 89%
  • Wounds and Injuries 42%
  • Inflammation Mediators 18%
  • Cell Lineage 15%

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  National Institute on Aging

  6/15/20 → 3/31/22

  Project: Research project

  • Gait 100%
  • Dementia 69%
  • Cognitive Dysfunction 67%
  • Brain 42%
  • Social Networking 30%

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  National Heart, Lung, and Blood Institute

  4/3/20 → 3/31/22

  Project: Research project

  • Cardiac Myocytes 100%
  • Pressure 69%
  • Heart 61%
  • Fibroblasts 59%
  • Transforming Growth Factor beta 55%

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  3/1/20 → 1/31/22

  Project: Research project

  • Vascular Remodeling 100%
  • Smooth Muscle Myocytes 96%
  • Electron Transport Complex I 54%
  • Embryonic Development 27%
  • Vascular Diseases 19%

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  National Institute of Mental Health

  3/1/20 → 1/31/22

  Project: Research project

  • HIV 100%
  • Technology 50%
  • Therapeutics 14%
  • Internet-Based Intervention 14%
  • HIV Infections 9%