Abstract
Glucose uptake by all cells in the organism by glucose transport proteins is among the most essential processes in life. The process of glucose uptake into tissues is performed by glucose transporters. This review focuses on the biology of facilitative glucose transporters (GLUTs). The knowledge that has accumulated for more than a decade with respect to the regulation of GLUT expression and function in various experimental conditions points to the great potential for GLUTs to be utilized as targets for designing therapies for treatment of diseases related to impaired regulation of glucose homeostasis including type 2 diabetes.
Original language | English (US) |
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Pages (from-to) | 163-172 |
Number of pages | 10 |
Journal | Biochemistry and Molecular Biology Education |
Volume | 31 |
Issue number | 3 |
DOIs | |
State | Published - May 2003 |
Keywords
- Diabetes
- GLUT
- Glucose uptake
- Insulin action
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology