Wearable long-term mechanical support for patients with end-stage heart disease

A tenable goal

Eric A. Rose, Daniel J. Goldstein

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Increasing in frequency, and claiming more than 250,000 lives per year, heart failure represents a major public health problem. In spite of newer medical therapies, a significant proportion of patients progress to irreversible end-stage heart disease, for which cardiac transplantation remains the only long term hope. The inability to meet the demand for donor organs has led to the development of left ventricular assist devices as a temporizing measure while awaiting a transplantation. The 'bridging to transplantation' experience has firmly established the efficacy of these devices as short-term and medium-term mechanical assistance and has provided valuable lessons applicable to long-term support. Mechanical cardiac assistance technology has dramatically improved and can provide reliable univentricular support with minimal thromboembolic and infectious complications. Although major obstacles remain, the potential benefits are great enough and the morbidity and mortality of end-stage heart disease high enough to warrant the evaluation of wearable left ventricular assist devices for long-term mechanical assistance.

Original languageEnglish (US)
Pages (from-to)399-402
Number of pages4
JournalAnnals of Thoracic Surgery
Volume61
Issue number1
DOIs
StatePublished - Jan 1996
Externally publishedYes

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Heart-Assist Devices
Heart Diseases
Transplantation
Heart Transplantation
Heart Failure
Public Health
Tissue Donors
Technology
Morbidity
Equipment and Supplies
Mortality
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Wearable long-term mechanical support for patients with end-stage heart disease : A tenable goal. / Rose, Eric A.; Goldstein, Daniel J.

In: Annals of Thoracic Surgery, Vol. 61, No. 1, 01.1996, p. 399-402.

Research output: Contribution to journalArticle

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