Venous thromboembolism in chronic kidney disease: epidemiology, the role of proteinuria, CKD severity and therapeutics

Chrisanna Dobrowolski, Edward G. Clark, Manish M. Sood

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

The worldwide prevalence of chronic kidney disease is 10–15 % of the adult population, is rising and increases susceptibility to venous thromboembolism (VTE). In this narrative review we discuss the underlying evidence behind the association of VTE/CKD and examine the role of worsening CKD stage, proteinuria, and the risk of recurrent VTE. As CKD may alter therapeutic options we discuss the role of emerging therapies, the non-vitamin K oral anticoagulants (NOAC), in the treatment of VTE.

Original languageEnglish (US)
Pages (from-to)241-247
Number of pages7
JournalJournal of Thrombosis and Thrombolysis
Volume43
Issue number2
DOIs
StatePublished - Feb 1 2017
Externally publishedYes

Keywords

  • Albuminuria
  • Chronic kidney disease
  • Epidemiology
  • Non-vitamin K antagonist oral anticoagulants
  • Venous thromboembolism

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine

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