TY - JOUR
T1 - Venous thromboembolism in chronic kidney disease
T2 - epidemiology, the role of proteinuria, CKD severity and therapeutics
AU - Dobrowolski, Chrisanna
AU - Clark, Edward G.
AU - Sood, Manish M.
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - The worldwide prevalence of chronic kidney disease is 10–15 % of the adult population, is rising and increases susceptibility to venous thromboembolism (VTE). In this narrative review we discuss the underlying evidence behind the association of VTE/CKD and examine the role of worsening CKD stage, proteinuria, and the risk of recurrent VTE. As CKD may alter therapeutic options we discuss the role of emerging therapies, the non-vitamin K oral anticoagulants (NOAC), in the treatment of VTE.
AB - The worldwide prevalence of chronic kidney disease is 10–15 % of the adult population, is rising and increases susceptibility to venous thromboembolism (VTE). In this narrative review we discuss the underlying evidence behind the association of VTE/CKD and examine the role of worsening CKD stage, proteinuria, and the risk of recurrent VTE. As CKD may alter therapeutic options we discuss the role of emerging therapies, the non-vitamin K oral anticoagulants (NOAC), in the treatment of VTE.
KW - Albuminuria
KW - Chronic kidney disease
KW - Epidemiology
KW - Non-vitamin K antagonist oral anticoagulants
KW - Venous thromboembolism
UR - http://www.scopus.com/inward/record.url?scp=84991105128&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84991105128&partnerID=8YFLogxK
U2 - 10.1007/s11239-016-1437-1
DO - 10.1007/s11239-016-1437-1
M3 - Review article
C2 - 27738784
AN - SCOPUS:84991105128
SN - 0929-5305
VL - 43
SP - 241
EP - 247
JO - Journal of Thrombosis and Thrombolysis
JF - Journal of Thrombosis and Thrombolysis
IS - 2
ER -