Use of ototopical antibiotics in treating 3 common ear diseases

Maureen T. Hannley, James C. Denneny, Susan Sedory Holzer, Michael Poole, Joseph E. Dohar, N. Wendell Todd, Harry Keyserling, Jennifer Rubin-Grandis, Leonard P. Rybak, Neil O. Ward, Robert J. Ruben, David L. Witsell, Susan E. Clift, Seth M. Pransky

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Prompted by rising rates of antibiotic resistance, lack of standardized treatment regimens, and new treatment alternatives, the American Academy of Otolaryngology-Head and Neck Surgery convened an expert consensus panel to consider recommendations for the responsible use of antibiotics in chronic suppurative otitis media, tympanostomy tube otorrhea, and otitis externa. The panel-concluded that in the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first-line treatment for most patients with these conditions, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone. Topical preparations should be selected on the basis of expected bacteriology and informed knowledge of the risk-benefit of each available preparation. The use of nonototoxic preparations in treating acute otitis externa (when the tympanic membrane is perforated or its status is unknown), chronic suppurative otitis media, and tympanostomy tube otorrhea should be considered.

Original languageEnglish (US)
Pages (from-to)934-940
Number of pages7
JournalOtolaryngology - Head and Neck Surgery
Volume122
Issue number6
StatePublished - 2000

Fingerprint

Ear Diseases
Middle Ear Ventilation
Suppurative Otitis Media
Anti-Bacterial Agents
Otitis Externa
Tympanic Membrane
Bacteriology
Otolaryngology
Microbial Drug Resistance
Neck
Therapeutics
Head
Infection

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Hannley, M. T., Denneny, J. C., Holzer, S. S., Poole, M., Dohar, J. E., Todd, N. W., ... Pransky, S. M. (2000). Use of ototopical antibiotics in treating 3 common ear diseases. Otolaryngology - Head and Neck Surgery, 122(6), 934-940.

Use of ototopical antibiotics in treating 3 common ear diseases. / Hannley, Maureen T.; Denneny, James C.; Holzer, Susan Sedory; Poole, Michael; Dohar, Joseph E.; Todd, N. Wendell; Keyserling, Harry; Rubin-Grandis, Jennifer; Rybak, Leonard P.; Ward, Neil O.; Ruben, Robert J.; Witsell, David L.; Clift, Susan E.; Pransky, Seth M.

In: Otolaryngology - Head and Neck Surgery, Vol. 122, No. 6, 2000, p. 934-940.

Research output: Contribution to journalArticle

Hannley, MT, Denneny, JC, Holzer, SS, Poole, M, Dohar, JE, Todd, NW, Keyserling, H, Rubin-Grandis, J, Rybak, LP, Ward, NO, Ruben, RJ, Witsell, DL, Clift, SE & Pransky, SM 2000, 'Use of ototopical antibiotics in treating 3 common ear diseases', Otolaryngology - Head and Neck Surgery, vol. 122, no. 6, pp. 934-940.
Hannley MT, Denneny JC, Holzer SS, Poole M, Dohar JE, Todd NW et al. Use of ototopical antibiotics in treating 3 common ear diseases. Otolaryngology - Head and Neck Surgery. 2000;122(6):934-940.
Hannley, Maureen T. ; Denneny, James C. ; Holzer, Susan Sedory ; Poole, Michael ; Dohar, Joseph E. ; Todd, N. Wendell ; Keyserling, Harry ; Rubin-Grandis, Jennifer ; Rybak, Leonard P. ; Ward, Neil O. ; Ruben, Robert J. ; Witsell, David L. ; Clift, Susan E. ; Pransky, Seth M. / Use of ototopical antibiotics in treating 3 common ear diseases. In: Otolaryngology - Head and Neck Surgery. 2000 ; Vol. 122, No. 6. pp. 934-940.
@article{c716c07583fa4e09be3babce3f16b6ba,
title = "Use of ototopical antibiotics in treating 3 common ear diseases",
abstract = "Prompted by rising rates of antibiotic resistance, lack of standardized treatment regimens, and new treatment alternatives, the American Academy of Otolaryngology-Head and Neck Surgery convened an expert consensus panel to consider recommendations for the responsible use of antibiotics in chronic suppurative otitis media, tympanostomy tube otorrhea, and otitis externa. The panel-concluded that in the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first-line treatment for most patients with these conditions, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone. Topical preparations should be selected on the basis of expected bacteriology and informed knowledge of the risk-benefit of each available preparation. The use of nonototoxic preparations in treating acute otitis externa (when the tympanic membrane is perforated or its status is unknown), chronic suppurative otitis media, and tympanostomy tube otorrhea should be considered.",
author = "Hannley, {Maureen T.} and Denneny, {James C.} and Holzer, {Susan Sedory} and Michael Poole and Dohar, {Joseph E.} and Todd, {N. Wendell} and Harry Keyserling and Jennifer Rubin-Grandis and Rybak, {Leonard P.} and Ward, {Neil O.} and Ruben, {Robert J.} and Witsell, {David L.} and Clift, {Susan E.} and Pransky, {Seth M.}",
year = "2000",
language = "English (US)",
volume = "122",
pages = "934--940",
journal = "Otolaryngology - Head and Neck Surgery (United States)",
issn = "0194-5998",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Use of ototopical antibiotics in treating 3 common ear diseases

AU - Hannley, Maureen T.

AU - Denneny, James C.

AU - Holzer, Susan Sedory

AU - Poole, Michael

AU - Dohar, Joseph E.

AU - Todd, N. Wendell

AU - Keyserling, Harry

AU - Rubin-Grandis, Jennifer

AU - Rybak, Leonard P.

AU - Ward, Neil O.

AU - Ruben, Robert J.

AU - Witsell, David L.

AU - Clift, Susan E.

AU - Pransky, Seth M.

PY - 2000

Y1 - 2000

N2 - Prompted by rising rates of antibiotic resistance, lack of standardized treatment regimens, and new treatment alternatives, the American Academy of Otolaryngology-Head and Neck Surgery convened an expert consensus panel to consider recommendations for the responsible use of antibiotics in chronic suppurative otitis media, tympanostomy tube otorrhea, and otitis externa. The panel-concluded that in the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first-line treatment for most patients with these conditions, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone. Topical preparations should be selected on the basis of expected bacteriology and informed knowledge of the risk-benefit of each available preparation. The use of nonototoxic preparations in treating acute otitis externa (when the tympanic membrane is perforated or its status is unknown), chronic suppurative otitis media, and tympanostomy tube otorrhea should be considered.

AB - Prompted by rising rates of antibiotic resistance, lack of standardized treatment regimens, and new treatment alternatives, the American Academy of Otolaryngology-Head and Neck Surgery convened an expert consensus panel to consider recommendations for the responsible use of antibiotics in chronic suppurative otitis media, tympanostomy tube otorrhea, and otitis externa. The panel-concluded that in the absence of systemic infection or serious underlying disease, topical antibiotics alone constitute first-line treatment for most patients with these conditions, finding no evidence that systemic antibiotics alone or in combination with topical preparations improve treatment outcomes compared with topical antibiotics alone. Topical preparations should be selected on the basis of expected bacteriology and informed knowledge of the risk-benefit of each available preparation. The use of nonototoxic preparations in treating acute otitis externa (when the tympanic membrane is perforated or its status is unknown), chronic suppurative otitis media, and tympanostomy tube otorrhea should be considered.

UR - http://www.scopus.com/inward/record.url?scp=0009955046&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0009955046&partnerID=8YFLogxK

M3 - Article

C2 - 10828818

AN - SCOPUS:0009955046

VL - 122

SP - 934

EP - 940

JO - Otolaryngology - Head and Neck Surgery (United States)

JF - Otolaryngology - Head and Neck Surgery (United States)

SN - 0194-5998

IS - 6

ER -