TY - JOUR
T1 - Twelfth Interagency Registry for Mechanically Assisted Circulatory Support Report
T2 - Readmissions After Left Ventricular Assist Device
AU - Shah, Palak
AU - Yuzefpolskaya, Melana
AU - Hickey, Gavin W.
AU - Breathett, Khadijah
AU - Wever-Pinzon, Omar
AU - Khue-Ton, Van
AU - Hiesinger, William
AU - Koehl, Devin
AU - Kirklin, James K.
AU - Cantor, Ryan S.
AU - Jacobs, Jeffrey P.
AU - Habib, Robert H.
AU - Pagani, Francis D.
AU - Goldstein, Daniel J.
N1 - Funding Information:
Palak Shah has a National Institutes of Health (NIH) Career Development Award from the National Heart, Lung, and Blood Institute (NHLBI) 1K23HL143179 and reports unrelated grant support from Roche and Abbott. Omar Wever-Pinzon has research funding from NIH NHLBI grant 5K23HL150322. Van Khue-Ton reports an unrelated research grant from Medtronic. Khadijah Breathett receives research funding from NIH NHLBI grants R56HL159216, K01HL142848, and L30HL148881 and Women as One Escalator Award. Francis D. Pagani receives research funding from NIH NHLBI R01HL146619 and Agency for Healthcare Research and Quality (AHRQ) R01HS026003. Francis D. Pagani is a noncompensated scientific advisor for FineHeart, CHBiomedical, Medtronic, and Abbott, a data safety monitoring board member for Carmat and NIH, Pumps for Kids, Infants and Neonates (PumpKIN) study. Daniel J. Goldstein serves as the National Co-Principal Investigator for the MOMENTUM 3 trial.
Publisher Copyright:
© 2022 The Society of Thoracic Surgeons
PY - 2022/3
Y1 - 2022/3
N2 - The twelfth annual report from The Society of Thoracic Surgeons (STS) Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) highlights outcomes for 26 688 continuous-flow left ventricular assist device (LVAD) patients over the past decade (2011-2020). In 2020, we observed the largest drop in yearly LVAD implant volumes since the registry's inception, which reflects the effects of the COVID-19 pandemic on cardiac surgical volumes in the United States. The 2018 heart transplant allocation policy change in the United States continues to affect LVAD implantation volumes and device strategy, with 78.1% of patients now receiving LVAD implants as destination therapy. Despite an older and sicker patient cohort, survival in the recent era (2016-2020) at 1 and 2 years continues to improve at 82.8% and 74.1%. Patient adverse event profile has also improved in the recent era, with significant reductions in stroke, gastrointestinal bleeding, infection, and device malfunction/pump thrombosis. Finally, we review the burden of readmissions after LVAD implant and highlight an opportunity to improve patient outcomes by reducing this frequent and vexing problem.
AB - The twelfth annual report from The Society of Thoracic Surgeons (STS) Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) highlights outcomes for 26 688 continuous-flow left ventricular assist device (LVAD) patients over the past decade (2011-2020). In 2020, we observed the largest drop in yearly LVAD implant volumes since the registry's inception, which reflects the effects of the COVID-19 pandemic on cardiac surgical volumes in the United States. The 2018 heart transplant allocation policy change in the United States continues to affect LVAD implantation volumes and device strategy, with 78.1% of patients now receiving LVAD implants as destination therapy. Despite an older and sicker patient cohort, survival in the recent era (2016-2020) at 1 and 2 years continues to improve at 82.8% and 74.1%. Patient adverse event profile has also improved in the recent era, with significant reductions in stroke, gastrointestinal bleeding, infection, and device malfunction/pump thrombosis. Finally, we review the burden of readmissions after LVAD implant and highlight an opportunity to improve patient outcomes by reducing this frequent and vexing problem.
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U2 - 10.1016/j.athoracsur.2021.12.011
DO - 10.1016/j.athoracsur.2021.12.011
M3 - Article
C2 - 35007505
AN - SCOPUS:85123199406
SN - 0003-4975
VL - 113
SP - 722
EP - 737
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -