Tubing failure during prolonged roller pump use: A laboratory study

Giles J. Peek, Kim Wong, Colin Morrison, Hilliary M. Killer, Richard K. Firmin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Little is known about the mechanical forces acting on extracorporeal circuit tubing with prolonged roller pump use during extracorporeal membrane oxygenation (ECMO). We examined the time to tubing rupture of three different materials during actual roller pump use, mean and standard deviation (SD) (SD shown in parentheses): Tygone® (control) 243.7 h (175.4); LVA 121 h (14.3); and SRT 6.6 h (2.1). Failure times for both LVA and SRT were significantly different from the control (paired t-test, p = 0.02 and p < 0.001, respectively). The minimum failure times for Tygon and LVA were 99 and 101 h, respectively. We then examined Tygon under conditions of pure compression, demonstrating that even after 3.67 million compression cycles at full occlusion crack formation did not occur. If the tubing was over-occluded, cracks appeared within 24 h. Scanning electron microscopy of Tygon, which has been used during clinical ECMO, and the failure pattern during destruction testing demonstrate that shear stress and compression coexist during clinical ECMO. Use of under-occlusive pump settings could improve tubing life.

Original languageEnglish (US)
Pages (from-to)443-452
Number of pages10
JournalPerfusion
Volume14
Issue number6
StatePublished - 1999
Externally publishedYes

Fingerprint

Extracorporeal Membrane Oxygenation
Tubing
Oxygenation
Pumps
Membranes
Electron Scanning Microscopy
Rupture
Crack initiation
Shear stress
Compaction
Cracks
Scanning electron microscopy
time
Networks (circuits)
Testing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Peek, G. J., Wong, K., Morrison, C., Killer, H. M., & Firmin, R. K. (1999). Tubing failure during prolonged roller pump use: A laboratory study. Perfusion, 14(6), 443-452.

Tubing failure during prolonged roller pump use : A laboratory study. / Peek, Giles J.; Wong, Kim; Morrison, Colin; Killer, Hilliary M.; Firmin, Richard K.

In: Perfusion, Vol. 14, No. 6, 1999, p. 443-452.

Research output: Contribution to journalArticle

Peek, GJ, Wong, K, Morrison, C, Killer, HM & Firmin, RK 1999, 'Tubing failure during prolonged roller pump use: A laboratory study', Perfusion, vol. 14, no. 6, pp. 443-452.
Peek GJ, Wong K, Morrison C, Killer HM, Firmin RK. Tubing failure during prolonged roller pump use: A laboratory study. Perfusion. 1999;14(6):443-452.
Peek, Giles J. ; Wong, Kim ; Morrison, Colin ; Killer, Hilliary M. ; Firmin, Richard K. / Tubing failure during prolonged roller pump use : A laboratory study. In: Perfusion. 1999 ; Vol. 14, No. 6. pp. 443-452.
@article{83214da8d1714434a5a7c6d8bb08d1f0,
title = "Tubing failure during prolonged roller pump use: A laboratory study",
abstract = "Little is known about the mechanical forces acting on extracorporeal circuit tubing with prolonged roller pump use during extracorporeal membrane oxygenation (ECMO). We examined the time to tubing rupture of three different materials during actual roller pump use, mean and standard deviation (SD) (SD shown in parentheses): Tygone{\circledR} (control) 243.7 h (175.4); LVA 121 h (14.3); and SRT 6.6 h (2.1). Failure times for both LVA and SRT were significantly different from the control (paired t-test, p = 0.02 and p < 0.001, respectively). The minimum failure times for Tygon and LVA were 99 and 101 h, respectively. We then examined Tygon under conditions of pure compression, demonstrating that even after 3.67 million compression cycles at full occlusion crack formation did not occur. If the tubing was over-occluded, cracks appeared within 24 h. Scanning electron microscopy of Tygon, which has been used during clinical ECMO, and the failure pattern during destruction testing demonstrate that shear stress and compression coexist during clinical ECMO. Use of under-occlusive pump settings could improve tubing life.",
author = "Peek, {Giles J.} and Kim Wong and Colin Morrison and Killer, {Hilliary M.} and Firmin, {Richard K.}",
year = "1999",
language = "English (US)",
volume = "14",
pages = "443--452",
journal = "Perfusion",
issn = "0267-6591",
publisher = "SAGE Publications Ltd",
number = "6",

}

TY - JOUR

T1 - Tubing failure during prolonged roller pump use

T2 - A laboratory study

AU - Peek, Giles J.

AU - Wong, Kim

AU - Morrison, Colin

AU - Killer, Hilliary M.

AU - Firmin, Richard K.

PY - 1999

Y1 - 1999

N2 - Little is known about the mechanical forces acting on extracorporeal circuit tubing with prolonged roller pump use during extracorporeal membrane oxygenation (ECMO). We examined the time to tubing rupture of three different materials during actual roller pump use, mean and standard deviation (SD) (SD shown in parentheses): Tygone® (control) 243.7 h (175.4); LVA 121 h (14.3); and SRT 6.6 h (2.1). Failure times for both LVA and SRT were significantly different from the control (paired t-test, p = 0.02 and p < 0.001, respectively). The minimum failure times for Tygon and LVA were 99 and 101 h, respectively. We then examined Tygon under conditions of pure compression, demonstrating that even after 3.67 million compression cycles at full occlusion crack formation did not occur. If the tubing was over-occluded, cracks appeared within 24 h. Scanning electron microscopy of Tygon, which has been used during clinical ECMO, and the failure pattern during destruction testing demonstrate that shear stress and compression coexist during clinical ECMO. Use of under-occlusive pump settings could improve tubing life.

AB - Little is known about the mechanical forces acting on extracorporeal circuit tubing with prolonged roller pump use during extracorporeal membrane oxygenation (ECMO). We examined the time to tubing rupture of three different materials during actual roller pump use, mean and standard deviation (SD) (SD shown in parentheses): Tygone® (control) 243.7 h (175.4); LVA 121 h (14.3); and SRT 6.6 h (2.1). Failure times for both LVA and SRT were significantly different from the control (paired t-test, p = 0.02 and p < 0.001, respectively). The minimum failure times for Tygon and LVA were 99 and 101 h, respectively. We then examined Tygon under conditions of pure compression, demonstrating that even after 3.67 million compression cycles at full occlusion crack formation did not occur. If the tubing was over-occluded, cracks appeared within 24 h. Scanning electron microscopy of Tygon, which has been used during clinical ECMO, and the failure pattern during destruction testing demonstrate that shear stress and compression coexist during clinical ECMO. Use of under-occlusive pump settings could improve tubing life.

UR - http://www.scopus.com/inward/record.url?scp=0032743683&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032743683&partnerID=8YFLogxK

M3 - Article

C2 - 10585152

AN - SCOPUS:0032743683

VL - 14

SP - 443

EP - 452

JO - Perfusion

JF - Perfusion

SN - 0267-6591

IS - 6

ER -