Tuberculosis treatment failure in AIDS: Vengeance with renal and ocular manifestations

Muhammad Ahsan Saeed; Hanan Tahir Lodhi; Faisal Inayat; Stephen Walters; Marilou Corpuz

doi:10.1136/bcr-2018-225955

Tuberculosis treatment failure in AIDS: Vengeance with renal and ocular manifestations

Muhammad Ahsan Saeed, Hanan Tahir Lodhi, Faisal Inayat, Stephen Walters, Marilou Corpuz

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Tuberculosis treatment failure is not uncommon in patients with AIDS. Treatment failure is defined as a positive sputum smear or culture at month 5 or later in the course of the treatment. The clinical presentations in these patients show remarkable heterogeneity. In this report, we chronicle the case of a patient with treatment failure presenting as the disseminated disease, specifically ocular and renal tuberculosis. Additionally, we undertake here a brief literature review highlighting the increased resistance to tuberculosis treatment in patients with AIDS, the rarity of ocular tuberculosis and the importance of tailoring drug regimens on an individual basis in these coinfected patients.

Original language	English (US)
Article number	432
Journal	BMJ case reports
Volume	2018
DOIs	https://doi.org/10.1136/bcr-2018-225955
State	Published - 2018

Keywords

HIV/AIDS
tb and other respiratory infections

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/bcr-2018-225955

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abstract = "Tuberculosis treatment failure is not uncommon in patients with AIDS. Treatment failure is defined as a positive sputum smear or culture at month 5 or later in the course of the treatment. The clinical presentations in these patients show remarkable heterogeneity. In this report, we chronicle the case of a patient with treatment failure presenting as the disseminated disease, specifically ocular and renal tuberculosis. Additionally, we undertake here a brief literature review highlighting the increased resistance to tuberculosis treatment in patients with AIDS, the rarity of ocular tuberculosis and the importance of tailoring drug regimens on an individual basis in these coinfected patients.",

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AU - Lodhi, Hanan Tahir

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AU - Walters, Stephen

AU - Corpuz, Marilou

N1 - Publisher Copyright: © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

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N2 - Tuberculosis treatment failure is not uncommon in patients with AIDS. Treatment failure is defined as a positive sputum smear or culture at month 5 or later in the course of the treatment. The clinical presentations in these patients show remarkable heterogeneity. In this report, we chronicle the case of a patient with treatment failure presenting as the disseminated disease, specifically ocular and renal tuberculosis. Additionally, we undertake here a brief literature review highlighting the increased resistance to tuberculosis treatment in patients with AIDS, the rarity of ocular tuberculosis and the importance of tailoring drug regimens on an individual basis in these coinfected patients.

AB - Tuberculosis treatment failure is not uncommon in patients with AIDS. Treatment failure is defined as a positive sputum smear or culture at month 5 or later in the course of the treatment. The clinical presentations in these patients show remarkable heterogeneity. In this report, we chronicle the case of a patient with treatment failure presenting as the disseminated disease, specifically ocular and renal tuberculosis. Additionally, we undertake here a brief literature review highlighting the increased resistance to tuberculosis treatment in patients with AIDS, the rarity of ocular tuberculosis and the importance of tailoring drug regimens on an individual basis in these coinfected patients.

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Tuberculosis treatment failure in AIDS: Vengeance with renal and ocular manifestations

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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