Treatment of high-grade squamous intraepithelial Lesion: A 2- verus 3-step approach

Lillian Berdichevsky, Randye Karmin, Linus Chuang

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Objective: The purpose of this study was to determine whether colposcopically directed biopsy is a necessary step in the evaluation of patients with high-grade squamous intraepithelial lesions. Study design: A retrospective analysis was conducted of the correlation between the high-grade squamous intraepithelial lesion Papanicolaou test and the colposcopically directed biopsy and the correlation between the high-grade squamous intraepithelial lesion Papanicolaou test and the loop electrosurgical excisional procedure. Results: Of 72 patients with high-grade squamous intraepithelial lesions on Papanicolaou test, 48 patients had a pathologic diagnosis on cervical biopsy of CIN II or greater, which provides a 67% correlation between the Papanicolaou test and the colposcopically directed biopsy. Fifty-six patients had a pathologic diagnosis on loop electrosurgical excisional procedure of CIN II or greater, which provides a 78% correlation between the Papanicolaou test and the loop electrosurgical excisional procedure. The median interval between the Papanicolaou test and the definitive treatment was significantly longer (P < .001) when colposcopically directed biopsy was performed before the loop electrosurgical excisional procedure. Conclusion: The colposcopically directed loop electrosurgical excisional procedure after a high-grade squamous intraepithelial lesion Papanicolaou test may reduce the time interval between diagnosis and treatment; furthermore, it offers equal correlation when compared with traditional treatment.

Original languageEnglish (US)
Pages (from-to)1424-1426
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume190
Issue number5
DOIs
StatePublished - May 2004

Keywords

  • High-grade squamous intraepithelial lesion
  • Loop electrosurgical excisional procedure

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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