Tiagabine is a novel antiepileptic drug that was designed to block gamma-aminobutyric acid uptake by presynaptic neurons and glial cells. It has been shown to be effective against partial seizures In adults and adolescents. Preliminary pediatric data are also encouraging. This article reviews the available animal and human data on the pharmacokinetics, efficacy, and safety of tiagabine.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology