Thy‐1 determinants are present on many murine hematopoietic Cells other than T Cells

Ross S. Basch, Joan W. Berman

Research output: Contribution to journalArticle

74 Scopus citations

Abstract

The development of a highly amplified immunofluorescence assay and the availability of monoclonal anti‐Thy‐1 antibodies have provided the methodology to reexamine the presence of Thy‐1 antigen on murine lymphohematopoietic cells. The representation of this antigen is not, as previously believed, restricted to the T cell compartment of these cells. It is present on a significant number of mouse bone marrow cells (25–30%), including, as in the rat, multipotential stem cells, prothymocytes and some B cell precursors. Eosinophils and some immature myeloid cells are also antigen‐positive.

Original languageEnglish (US)
Pages (from-to)359-364
Number of pages6
JournalEuropean Journal of Immunology
Volume12
Issue number5
DOIs
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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