Three new MHC haplotypes in broiler breeder chickens

E. J. Livant, D. Zheng, L. W. Johnson, W. Shi, S. J. Ewald

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B-G restriction fragment length polymorphism (RFLP) analysis, allele-specific PCR typing test for B-LBII family genes and nucleotide sequence analysis of expressed B-F and B-LBH family genes. The results indicated the existence of seven distinct B haplotypes. Nucleotide sequence analysis demonstrated that three of the Line C haplotypes encode new B-F and B-LB alleles.

Original languageEnglish (US)
Pages (from-to)123-131
Number of pages9
JournalAnimal Genetics
Volume32
Issue number3
DOIs
StatePublished - Aug 29 2001
Externally publishedYes

Keywords

  • Broiler
  • Chicken
  • Class I
  • Class II
  • Major histocompatibility complex
  • PCR-SSP

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Genetics

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