The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

M. Schwartz; R. Jewelewicz; I. Dyrenfurth; P. Tropper; R. L. Vande Wiele

doi:10.1016/S0002-9378(16)32740-5

The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

M. Schwartz, R. Jewelewicz, I. Dyrenfurth, P. Tropper, R. L. Vande Wiele

Obstetrics & Gynecology and Women's Health

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.

Original language	English (US)
Pages (from-to)	801-807
Number of pages	7
Journal	Unknown Journal
Volume	138
Issue number	7 I
DOIs	https://doi.org/10.1016/S0002-9378(16)32740-5
State	Published - Jan 1 1980

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/S0002-9378(16)32740-5

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abstract = "Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.",

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The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

Abstract

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