The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

M. Schwartz, R. Jewelewicz, I. Dyrenfurth, P. Tropper, R. L. Vande Wiele

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.

Original languageEnglish (US)
Pages (from-to)801-807
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume138
Issue number7 I
StatePublished - 1980
Externally publishedYes

Fingerprint

Menotropins
Ovulation Induction
Chorionic Gonadotropin
Multiple Pregnancy
Pregnancy Rate
Gonadotropins
Galactorrhea
Anovulation
Hypogonadism
Induced Abortion
Amenorrhea
Spontaneous Abortion
Estrogens
Therapeutics
Pregnancy

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women. / Schwartz, M.; Jewelewicz, R.; Dyrenfurth, I.; Tropper, P.; Vande Wiele, R. L.

In: American Journal of Obstetrics and Gynecology, Vol. 138, No. 7 I, 1980, p. 801-807.

Research output: Contribution to journalArticle

Schwartz, M. ; Jewelewicz, R. ; Dyrenfurth, I. ; Tropper, P. ; Vande Wiele, R. L. / The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women. In: American Journal of Obstetrics and Gynecology. 1980 ; Vol. 138, No. 7 I. pp. 801-807.
@article{17f65a05c62d44dbb866225da558ba9a,
title = "The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women",
abstract = "Gonadotropin therapy for anovulation is highly successful: 58.6{\%} of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1{\%}) and hypogonadotropic hypogonadism (63.3{\%}) than in patients with normal gonadotropin levels (45.4{\%}). The spontaneous abortion rate (27.5{\%}) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31{\%} and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9{\%}) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.",
author = "M. Schwartz and R. Jewelewicz and I. Dyrenfurth and P. Tropper and {Vande Wiele}, {R. L.}",
year = "1980",
language = "English (US)",
volume = "138",
pages = "801--807",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "7 I",

}

TY - JOUR

T1 - The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

AU - Schwartz, M.

AU - Jewelewicz, R.

AU - Dyrenfurth, I.

AU - Tropper, P.

AU - Vande Wiele, R. L.

PY - 1980

Y1 - 1980

N2 - Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.

AB - Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.

UR - http://www.scopus.com/inward/record.url?scp=0019132409&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019132409&partnerID=8YFLogxK

M3 - Article

VL - 138

SP - 801

EP - 807

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 7 I

ER -