The use of human menopausal and chorionic gonadotropins for induction of ovulation. Sixteen year' experience at the Sloane Hospital for Women

M. Schwartz, R. Jewelewicz, I. Dyrenfurth, P. Tropper, R. L. Vande Wiele

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Abstract

Gonadotropin therapy for anovulation is highly successful: 58.6% of treated patients conceive. Better results are achieved in patients with galactorrhea-amenorrhea (77.1%) and hypogonadotropic hypogonadism (63.3%) than in patients with normal gonadotropin levels (45.4%). The spontaneous abortion rate (27.5%) is somewhat higher than that in spontaneous pregnancies. The multiple pregnancy rate is 31% and was slightly lower in cycles with preovulatory estrogen levels in the physiologic range. In patients treated with human menopausal and chorionic gonadotropins for 7 to 9 days per cycle, the multiple pregnancy rate is considerably less (12.9%) than in patients with longer treatment. The efficacy of treatment does not diminish with repeat-treatment cycles.

Original languageEnglish (US)
Pages (from-to)801-807
Number of pages7
JournalUnknown Journal
Volume138
Issue number7 I
DOIs
Publication statusPublished - Jan 1 1980

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ASJC Scopus subject areas

  • Obstetrics and Gynecology

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