TY - JOUR
T1 - The spleen in the spleen syndrome
T2 - The association of splenoma with hematopoietic and neoplastic disease—compendium of cases since 1864
AU - Steinberg, J. J.
AU - Suhrland, Mark
AU - Valensi, Quentin
PY - 1991/7
Y1 - 1991/7
N2 - Splenomas have been described as benign congenital growths. We report six cases of splenomas, all in males. Three had hairy cell leukemia, one had Hodgkin's disease, and one had myeloid metaplasia. Average splenic weight was 1629 gm, and all had multiple splenomas (average diameter 1.89 cm). Splenomas bulged above the cut splenic surface, were pseudo‐encapsulated, and showed involvement of the underlying disease. A re‐evaluation of 105 prior cases are adult (86%; age: 49), with 56% associated with neoplastic disease or hematologic abnormalities. Average spleen weight was 626 gm, and 22% contained multiple splenomas. We conclude that splenomas are most likely an acquired proliferative process strongly associated with neoplastic disease or hematologic abnormalities. Splenomas can also be congenital growths (hamartoma; 26% of the series), which are of little importance.
AB - Splenomas have been described as benign congenital growths. We report six cases of splenomas, all in males. Three had hairy cell leukemia, one had Hodgkin's disease, and one had myeloid metaplasia. Average splenic weight was 1629 gm, and all had multiple splenomas (average diameter 1.89 cm). Splenomas bulged above the cut splenic surface, were pseudo‐encapsulated, and showed involvement of the underlying disease. A re‐evaluation of 105 prior cases are adult (86%; age: 49), with 56% associated with neoplastic disease or hematologic abnormalities. Average spleen weight was 626 gm, and 22% contained multiple splenomas. We conclude that splenomas are most likely an acquired proliferative process strongly associated with neoplastic disease or hematologic abnormalities. Splenomas can also be congenital growths (hamartoma; 26% of the series), which are of little importance.
KW - congenital growths
KW - hamartoma
KW - pathology
KW - radiography
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U2 - 10.1002/jso.2930470311
DO - 10.1002/jso.2930470311
M3 - Article
C2 - 2072704
AN - SCOPUS:0025781447
SN - 0022-4790
VL - 47
SP - 193
EP - 202
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 3
ER -