The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation

S. Takaya, T. Nonami, R. Selby, Howard Doyle, G. Murray, D. Kramer, Y. Kang, T. E. Starzl

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The early postoperative hemodynamic data of 88 patients who underwent primary liver transplantation between July 1989 and October 1990 at the University Health Center of Pittsburgh were analyzed to establish the relationship of systemic hemodynamics and oxygen consumption to perioperative allograft function. The 15 patients whose allografts failed within the 1 st month following transplantation were designated as group 1, while 73 patients who retained adequate graft function constituted group 2. Although the cardiac index and oxygen delivery did not differ significantly between the groups, group 1 consistently demonstrated a lower mean arterial pressure, oxygen consumption, arteriovenous oxygen content difference, and arterial ketone body ratio. The etiology of reduced oxygen consumption in group 1 patients is speculative, but the data support the notion that oxygen consumption is a useful, predictive indicator for liver allograft function after transplantation.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalTransplant International
Volume6
Issue number2
DOIs
StatePublished - Mar 1993
Externally publishedYes

Fingerprint

Oxygen Consumption
Liver Transplantation
Allografts
Hemodynamics
Transplantation
Oxygen
Ketone Bodies
Arterial Pressure
Transplants
Liver
Health

Keywords

  • Failure of liver transplantation, oxygen consumption
  • Liver transplantation, oxygen consumption
  • Oxygen consumption, liver transplantation failure

ASJC Scopus subject areas

  • Transplantation

Cite this

The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation. / Takaya, S.; Nonami, T.; Selby, R.; Doyle, Howard; Murray, G.; Kramer, D.; Kang, Y.; Starzl, T. E.

In: Transplant International, Vol. 6, No. 2, 03.1993, p. 73-76.

Research output: Contribution to journalArticle

Takaya, S. ; Nonami, T. ; Selby, R. ; Doyle, Howard ; Murray, G. ; Kramer, D. ; Kang, Y. ; Starzl, T. E. / The relationship of systemic hemodynamics and oxygen consumption to early allograft failure after liver transplantation. In: Transplant International. 1993 ; Vol. 6, No. 2. pp. 73-76.
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