TY - JOUR
T1 - The place of genetics in ageing research
AU - Barzilai, Nir
AU - Guarente, Leonard
AU - Kirkwood, Thomas B.L.
AU - Partridge, Linda
AU - Rando, Thomas A.
AU - Eline Slagboom, P. E.
N1 - Funding Information:
Nir Barzilai is the Director of the Institute for Aging Research at the Albert Einstein College of Medicine, New York City, New York, USA, and the principal investigator at a US National Institutes of Health (NIH) Nathan Shock Center of Excellence in Basic Biology of Aging. He is the Ingeborg and Ira Leon Rennert Professor of Aging Research and a professor of medicine and molecular genetics. His interests focus on several basic mechanisms in the biology of ageing, including the biological effects of nutrients on extending life and the genetic determinants of lifespan. He has associated several longevity genes in humans and is further characterizing the phenotype and genotype of humans with exceptional longevity through an NIH-supported program project. He received numerous grants, including from the US National Institute of Aging (NIA), the American Federation of Aging Research and the Ellison Medical Foundation. He serves on several editorial boards and is a reviewer for numerous other journals. He was a recipient of numerous prestigious awards, including the Beeson Fellow for Aging Research, the Senior Ellison Foundation award, the Paul Glenn Foundation award and the NIA Nathan Shock Award, as well as being the recipient of the 2010 Irving S. Wright Award of Distinction in ageing research.
PY - 2012/8
Y1 - 2012/8
N2 - Rapidly increasing numbers of older people present many countries with growing social and economic challenges. Yet despite the far-reaching implications of ageing, its biological basis remains a topic of much debate. Recent advances in genomics have spurred research on ageing and lifespan in human populations, adding to extensive genetic studies being carried out in model organisms. But how far is ageing controlled by our genes? In this Viewpoint, six experts present their opinions and comment on future directions in ageing research.
AB - Rapidly increasing numbers of older people present many countries with growing social and economic challenges. Yet despite the far-reaching implications of ageing, its biological basis remains a topic of much debate. Recent advances in genomics have spurred research on ageing and lifespan in human populations, adding to extensive genetic studies being carried out in model organisms. But how far is ageing controlled by our genes? In this Viewpoint, six experts present their opinions and comment on future directions in ageing research.
UR - http://www.scopus.com/inward/record.url?scp=84863988683&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84863988683&partnerID=8YFLogxK
U2 - 10.1038/nrg3290
DO - 10.1038/nrg3290
M3 - Review article
C2 - 22777128
AN - SCOPUS:84863988683
SN - 1471-0056
VL - 13
SP - 589
EP - 594
JO - Nature Reviews Genetics
JF - Nature Reviews Genetics
IS - 8
ER -