The migraine postdrome

Nicola J. Giffin, Richard B. Lipton, Stephen D. Silberstein, Jes Olesen, Peter J. Goadsby

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Objective: To report migraine postdrome symptoms in patients who report nonheadache symptoms as part of their attacks. Methods: A prospective daily electronic diary study was conducted over 3 months in 120 patients with migraine. Nonheadache symptoms before, during, and after headache were collected on a daily basis. Visual analogue scales were used to capture the overall level of functioning and the severity of the headache. The postdrome was defined as the time from resolution of troublesome headache to return to normal. Results: Of 120 evaluable patients, 97 (81%) reported at least one nonheadache symptom in the postdrome. Postdrome symptoms, in order of frequency, included feeling tired/weary and having difficulty concentrating and stiff neck. Many patients also reported a mild residual head discomfort. In most attacks (93%), there was return to normal within 24 hours after spontaneous pain resolved. There was no relationship between medication taken for the headache and the duration of the postdrome. The severity of the migraine was not associated with the duration of the postdrome. Overall state of health scores remained low during the postdrome. Conclusion: Nonheadache symptoms in the postdrome were common and may contribute to the distress and disability in the patients studied. Postdrome symptoms merit larger observational studies and careful recording in clinical trials of acute and preventive migraine treatments.

Original languageEnglish (US)
Pages (from-to)309-313
Number of pages5
JournalNeurology
Volume87
Issue number3
DOIs
StatePublished - Jul 19 2016

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Migraine Disorders
Headache
Visual Analog Scale
Observational Studies
Emotions
Neck
Head
Clinical Trials
Pain
Health
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Giffin, N. J., Lipton, R. B., Silberstein, S. D., Olesen, J., & Goadsby, P. J. (2016). The migraine postdrome. Neurology, 87(3), 309-313. https://doi.org/10.1212/WNL.0000000000002789

The migraine postdrome. / Giffin, Nicola J.; Lipton, Richard B.; Silberstein, Stephen D.; Olesen, Jes; Goadsby, Peter J.

In: Neurology, Vol. 87, No. 3, 19.07.2016, p. 309-313.

Research output: Contribution to journalArticle

Giffin, NJ, Lipton, RB, Silberstein, SD, Olesen, J & Goadsby, PJ 2016, 'The migraine postdrome', Neurology, vol. 87, no. 3, pp. 309-313. https://doi.org/10.1212/WNL.0000000000002789
Giffin NJ, Lipton RB, Silberstein SD, Olesen J, Goadsby PJ. The migraine postdrome. Neurology. 2016 Jul 19;87(3):309-313. https://doi.org/10.1212/WNL.0000000000002789
Giffin, Nicola J. ; Lipton, Richard B. ; Silberstein, Stephen D. ; Olesen, Jes ; Goadsby, Peter J. / The migraine postdrome. In: Neurology. 2016 ; Vol. 87, No. 3. pp. 309-313.
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