The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

W. K. Chung, A. Luke, R. S. Cooper, C. Rotini, A. Vidal-Puig, M. Rosenbaum, D. Gordon, S. M. Leal, S. Caprio, R. Goldsmith, A. L. Andreu, C. Bruno, S. DiMauro, Moonseong Heo, W. L. Lowe, B. B. Lowell, D. B. Allison, R. L. Leibel

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 > have been described in humans, but not in rodents. The functional consequences - or lack thereof - of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.

Original languageEnglish (US)
JournalInternational Journal of Obesity
Volume23
Issue numberSUPPL. 6
StatePublished - 1999
Externally publishedYes

Fingerprint

protein isoforms
homeostasis
Protein Isoforms
Homeostasis
mutation
Amino Acid Sequence Homology
Mutation
energy
sequence homology
Rodentia
rodents
amino acid sequences
Biological Sciences
Proteins
proteins
Uncoupling Protein 3

Keywords

  • Diabetes
  • Obesity
  • Skeletal muscle
  • Thermogenesis

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism

Cite this

Chung, W. K., Luke, A., Cooper, R. S., Rotini, C., Vidal-Puig, A., Rosenbaum, M., ... Leibel, R. L. (1999). The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis. International Journal of Obesity, 23(SUPPL. 6).

The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis. / Chung, W. K.; Luke, A.; Cooper, R. S.; Rotini, C.; Vidal-Puig, A.; Rosenbaum, M.; Gordon, D.; Leal, S. M.; Caprio, S.; Goldsmith, R.; Andreu, A. L.; Bruno, C.; DiMauro, S.; Heo, Moonseong; Lowe, W. L.; Lowell, B. B.; Allison, D. B.; Leibel, R. L.

In: International Journal of Obesity, Vol. 23, No. SUPPL. 6, 1999.

Research output: Contribution to journalArticle

Chung, WK, Luke, A, Cooper, RS, Rotini, C, Vidal-Puig, A, Rosenbaum, M, Gordon, D, Leal, SM, Caprio, S, Goldsmith, R, Andreu, AL, Bruno, C, DiMauro, S, Heo, M, Lowe, WL, Lowell, BB, Allison, DB & Leibel, RL 1999, 'The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis', International Journal of Obesity, vol. 23, no. SUPPL. 6.
Chung WK, Luke A, Cooper RS, Rotini C, Vidal-Puig A, Rosenbaum M et al. The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis. International Journal of Obesity. 1999;23(SUPPL. 6).
Chung, W. K. ; Luke, A. ; Cooper, R. S. ; Rotini, C. ; Vidal-Puig, A. ; Rosenbaum, M. ; Gordon, D. ; Leal, S. M. ; Caprio, S. ; Goldsmith, R. ; Andreu, A. L. ; Bruno, C. ; DiMauro, S. ; Heo, Moonseong ; Lowe, W. L. ; Lowell, B. B. ; Allison, D. B. ; Leibel, R. L. / The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis. In: International Journal of Obesity. 1999 ; Vol. 23, No. SUPPL. 6.
@article{9400e4bd561c41a1bb49afcb683ebc77,
title = "The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis",
abstract = "The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 > have been described in humans, but not in rodents. The functional consequences - or lack thereof - of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.",
keywords = "Diabetes, Obesity, Skeletal muscle, Thermogenesis",
author = "Chung, {W. K.} and A. Luke and Cooper, {R. S.} and C. Rotini and A. Vidal-Puig and M. Rosenbaum and D. Gordon and Leal, {S. M.} and S. Caprio and R. Goldsmith and Andreu, {A. L.} and C. Bruno and S. DiMauro and Moonseong Heo and Lowe, {W. L.} and Lowell, {B. B.} and Allison, {D. B.} and Leibel, {R. L.}",
year = "1999",
language = "English (US)",
volume = "23",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "Nature Publishing Group",
number = "SUPPL. 6",

}

TY - JOUR

T1 - The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

AU - Chung, W. K.

AU - Luke, A.

AU - Cooper, R. S.

AU - Rotini, C.

AU - Vidal-Puig, A.

AU - Rosenbaum, M.

AU - Gordon, D.

AU - Leal, S. M.

AU - Caprio, S.

AU - Goldsmith, R.

AU - Andreu, A. L.

AU - Bruno, C.

AU - DiMauro, S.

AU - Heo, Moonseong

AU - Lowe, W. L.

AU - Lowell, B. B.

AU - Allison, D. B.

AU - Leibel, R. L.

PY - 1999

Y1 - 1999

N2 - The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 > have been described in humans, but not in rodents. The functional consequences - or lack thereof - of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.

AB - The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 > have been described in humans, but not in rodents. The functional consequences - or lack thereof - of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.

KW - Diabetes

KW - Obesity

KW - Skeletal muscle

KW - Thermogenesis

UR - http://www.scopus.com/inward/record.url?scp=0033002467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033002467&partnerID=8YFLogxK

M3 - Article

VL - 23

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - SUPPL. 6

ER -