The interval between menarche and age of first sexual intercourse as a risk factor for subsequent HPV infection in adolescent and young adult women

Jessica A. Kahn, Susan L. Rosenthal, Paul A. Succop, Gloria Y F Ho, Robert D. Burk

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

We sought to determine whether the interval between menarche and age of first sexual intercourse is associated with subsequent human papilloma virus (HPV) infection and if so, whether the association is independent of the age of first sexual intercourse. Female university students completed a survey and were screened for cervicovaginal HPV infection. HPV-positive subjects were matched to HPV-negative subjects (n = 504). Mean subject age was 20.4 ± 2.1 years, age of first sexual intercourse 16.7 ± 1.8 years, and interval 4.4 ± 2.0 years. The interval was associated with HPV infection, but the association became nonsignificant in univariate stratified analyses and multivariate models estimating the association between the interval and HPV infection. A short interval is associated with HPV infection, but the association is not independent of age of first sexual intercourse. Age of first sexual intercourse should be considered an important and identifiable risk factor for subsequent HPV infection in research and clinical settings.

Original languageEnglish (US)
Pages (from-to)718-723
Number of pages6
JournalJournal of Pediatrics
Volume141
Issue number5
DOIs
StatePublished - Nov 1 2002

Fingerprint

Papillomaviridae
Menarche
Coitus
Virus Diseases
Young Adult

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

The interval between menarche and age of first sexual intercourse as a risk factor for subsequent HPV infection in adolescent and young adult women. / Kahn, Jessica A.; Rosenthal, Susan L.; Succop, Paul A.; Ho, Gloria Y F; Burk, Robert D.

In: Journal of Pediatrics, Vol. 141, No. 5, 01.11.2002, p. 718-723.

Research output: Contribution to journalArticle

@article{e016fe5e1a044ab7bd1516ffa4bc941c,
title = "The interval between menarche and age of first sexual intercourse as a risk factor for subsequent HPV infection in adolescent and young adult women",
abstract = "We sought to determine whether the interval between menarche and age of first sexual intercourse is associated with subsequent human papilloma virus (HPV) infection and if so, whether the association is independent of the age of first sexual intercourse. Female university students completed a survey and were screened for cervicovaginal HPV infection. HPV-positive subjects were matched to HPV-negative subjects (n = 504). Mean subject age was 20.4 ± 2.1 years, age of first sexual intercourse 16.7 ± 1.8 years, and interval 4.4 ± 2.0 years. The interval was associated with HPV infection, but the association became nonsignificant in univariate stratified analyses and multivariate models estimating the association between the interval and HPV infection. A short interval is associated with HPV infection, but the association is not independent of age of first sexual intercourse. Age of first sexual intercourse should be considered an important and identifiable risk factor for subsequent HPV infection in research and clinical settings.",
author = "Kahn, {Jessica A.} and Rosenthal, {Susan L.} and Succop, {Paul A.} and Ho, {Gloria Y F} and Burk, {Robert D.}",
year = "2002",
month = "11",
day = "1",
doi = "10.1067/mpd.2002.128893",
language = "English (US)",
volume = "141",
pages = "718--723",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - The interval between menarche and age of first sexual intercourse as a risk factor for subsequent HPV infection in adolescent and young adult women

AU - Kahn, Jessica A.

AU - Rosenthal, Susan L.

AU - Succop, Paul A.

AU - Ho, Gloria Y F

AU - Burk, Robert D.

PY - 2002/11/1

Y1 - 2002/11/1

N2 - We sought to determine whether the interval between menarche and age of first sexual intercourse is associated with subsequent human papilloma virus (HPV) infection and if so, whether the association is independent of the age of first sexual intercourse. Female university students completed a survey and were screened for cervicovaginal HPV infection. HPV-positive subjects were matched to HPV-negative subjects (n = 504). Mean subject age was 20.4 ± 2.1 years, age of first sexual intercourse 16.7 ± 1.8 years, and interval 4.4 ± 2.0 years. The interval was associated with HPV infection, but the association became nonsignificant in univariate stratified analyses and multivariate models estimating the association between the interval and HPV infection. A short interval is associated with HPV infection, but the association is not independent of age of first sexual intercourse. Age of first sexual intercourse should be considered an important and identifiable risk factor for subsequent HPV infection in research and clinical settings.

AB - We sought to determine whether the interval between menarche and age of first sexual intercourse is associated with subsequent human papilloma virus (HPV) infection and if so, whether the association is independent of the age of first sexual intercourse. Female university students completed a survey and were screened for cervicovaginal HPV infection. HPV-positive subjects were matched to HPV-negative subjects (n = 504). Mean subject age was 20.4 ± 2.1 years, age of first sexual intercourse 16.7 ± 1.8 years, and interval 4.4 ± 2.0 years. The interval was associated with HPV infection, but the association became nonsignificant in univariate stratified analyses and multivariate models estimating the association between the interval and HPV infection. A short interval is associated with HPV infection, but the association is not independent of age of first sexual intercourse. Age of first sexual intercourse should be considered an important and identifiable risk factor for subsequent HPV infection in research and clinical settings.

UR - http://www.scopus.com/inward/record.url?scp=0036843338&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036843338&partnerID=8YFLogxK

U2 - 10.1067/mpd.2002.128893

DO - 10.1067/mpd.2002.128893

M3 - Article

C2 - 12410205

AN - SCOPUS:0036843338

VL - 141

SP - 718

EP - 723

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 5

ER -