The genetics of polycystic ovary syndrome

Brad Eilerman, Marzieh Salehi, Yaron Tomer

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Polycystic ovary syndrome is one of the most common endocrine disorders in women, affecting up to 7% of women of reproductive age. It is characterized by chronic anovulation, hyperandrogenemia, and often obesity [1]. Key reproductive features of PCOS are disordered gonadotropin secretion [2], elevated ovarian and adrenal androgen production [3], and frequently polycystic ovaries. Women with PCOS have profound insulin resistance as well as beta cell dysfunction, regardless of obesity and glucose tolerance status [4].

Original languageEnglish (US)
Title of host publicationDiagnosis and Management of Polycystic Ovary Syndrome
PublisherSpringer US
Pages83-91
Number of pages9
ISBN (Print)9780387097176
DOIs
StatePublished - Dec 1 2009
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Eilerman, B., Salehi, M., & Tomer, Y. (2009). The genetics of polycystic ovary syndrome. In Diagnosis and Management of Polycystic Ovary Syndrome (pp. 83-91). Springer US. https://doi.org/10.1007/978-0-387-09718-3_6