The epidemiology of pediatric acquired immunodeficiency syndrome

Arye Rubinstein; Larry Bernstein

doi:10.1016/0090-1229(86)90074-7

The epidemiology of pediatric acquired immunodeficiency syndrome

Arye Rubinstein, Larry Bernstein

Pediatrics

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

HTLV III infection of children exhibits a relatively narrow spectrum in which the majority of patients develop clinical manifestations before the age of 2 years. In most instances the disease is transmitted in utero, whereby 35-65% of HTLV III-positive women give birth to an infected child. Discordant infection in twins is described. In fewer cases the disease is acquired through blood transfusions. In exceptional cases transmission via sexual abuse or use of needles may occur in young children. We have no evidence of intrafamilial horizontal disease transmission from child to child. The number of children with the disease may increase sharply. Around 2000 pregnancies in HTLV III-infected women are projected in New York City in the next year. Should all these pregnancies be completed, several hundred additional cases of pediatric AIDS may be expected in 1986.

Original language	English (US)
Pages (from-to)	115-121
Number of pages	7
Journal	Clinical Immunology and Immunopathology
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/0090-1229(86)90074-7
State	Published - Jul 1986

ASJC Scopus subject areas

Immunology and Allergy
Pathology and Forensic Medicine
Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0090-1229(86)90074-7

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title = "The epidemiology of pediatric acquired immunodeficiency syndrome",

abstract = "HTLV III infection of children exhibits a relatively narrow spectrum in which the majority of patients develop clinical manifestations before the age of 2 years. In most instances the disease is transmitted in utero, whereby 35-65% of HTLV III-positive women give birth to an infected child. Discordant infection in twins is described. In fewer cases the disease is acquired through blood transfusions. In exceptional cases transmission via sexual abuse or use of needles may occur in young children. We have no evidence of intrafamilial horizontal disease transmission from child to child. The number of children with the disease may increase sharply. Around 2000 pregnancies in HTLV III-infected women are projected in New York City in the next year. Should all these pregnancies be completed, several hundred additional cases of pediatric AIDS may be expected in 1986.",

author = "Arye Rubinstein and Larry Bernstein",

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AU - Bernstein, Larry

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AB - HTLV III infection of children exhibits a relatively narrow spectrum in which the majority of patients develop clinical manifestations before the age of 2 years. In most instances the disease is transmitted in utero, whereby 35-65% of HTLV III-positive women give birth to an infected child. Discordant infection in twins is described. In fewer cases the disease is acquired through blood transfusions. In exceptional cases transmission via sexual abuse or use of needles may occur in young children. We have no evidence of intrafamilial horizontal disease transmission from child to child. The number of children with the disease may increase sharply. Around 2000 pregnancies in HTLV III-infected women are projected in New York City in the next year. Should all these pregnancies be completed, several hundred additional cases of pediatric AIDS may be expected in 1986.

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The epidemiology of pediatric acquired immunodeficiency syndrome

Abstract

ASJC Scopus subject areas

UN SDGs

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