The efficacy of anal fistula plug in fistula-in-ano: a systematic review.

P. Garg, J. Song, A. Bhatia, Harmit S. Kalia, G. R. Menon

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

To assess the efficacy of anal fistula plug (AFP) procedure for the treatment of fistula-in-ano especially the complex fistulas. The database of PUBMED, MEDLINE, SCOPUS, EMBASE and COCHRANE LIBRARY for the period 1995-2009 was searched. A systematic analysis was carried to evaluate the success rate of AFP procedure in fistula-in-ano. A total of 25 studies were extracted and 12 (n = 317) were finally included in the systematic review. The follow-up period ranged from 3.5 to 12 months. The AFP procedure had a success rate (patient cure rate) ranging from 24% to 92%. In complex fistula-in-ano in prospective studies (8/12 studies), the success rate was 35-87%. The success rate in patients with Crohn's disease was 29-86%. The success rate in the patients with single tracts was 44-93% and in patients with multiple tracts, success ranged from 20% to 71%. The abscess formation/sepsis rate was 4-29% (11/108) and the plug extrusion rate was 4-41% (42/232-19%). Anal fistula plug procedure has a success rate ranging from 24% to 92% in different studies. In prospective studies of complex fistula-in-ano, there was a moderate success rate of 35-87%. As AFP is associated with low morbidity and sepsis, it appears to be a safe procedure. Further randomized controlled trials studying objective parameters of fistula healing are needed to substantiate these findings.

Original languageEnglish (US)
Pages (from-to)965-970
Number of pages6
JournalColorectal Disease
Volume12
Issue number10
StatePublished - Oct 2010
Externally publishedYes

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Rectal Fistula
Fistula
Sepsis
Prospective Studies
PubMed
MEDLINE
Crohn Disease
Abscess
Randomized Controlled Trials
Databases
Morbidity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Garg, P., Song, J., Bhatia, A., Kalia, H. S., & Menon, G. R. (2010). The efficacy of anal fistula plug in fistula-in-ano: a systematic review. Colorectal Disease, 12(10), 965-970.

The efficacy of anal fistula plug in fistula-in-ano : a systematic review. / Garg, P.; Song, J.; Bhatia, A.; Kalia, Harmit S.; Menon, G. R.

In: Colorectal Disease, Vol. 12, No. 10, 10.2010, p. 965-970.

Research output: Contribution to journalArticle

Garg, P, Song, J, Bhatia, A, Kalia, HS & Menon, GR 2010, 'The efficacy of anal fistula plug in fistula-in-ano: a systematic review.', Colorectal Disease, vol. 12, no. 10, pp. 965-970.
Garg P, Song J, Bhatia A, Kalia HS, Menon GR. The efficacy of anal fistula plug in fistula-in-ano: a systematic review. Colorectal Disease. 2010 Oct;12(10):965-970.
Garg, P. ; Song, J. ; Bhatia, A. ; Kalia, Harmit S. ; Menon, G. R. / The efficacy of anal fistula plug in fistula-in-ano : a systematic review. In: Colorectal Disease. 2010 ; Vol. 12, No. 10. pp. 965-970.
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