The effect of vasopressin on the cytoskeleton of the epithelial cell

Richard M. Hays, John S. Condeelis, Yang Gao, Herold Simon, Guohua Ding, Nicholas Franki

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Vasopressin (AVP) promotes the fusion of vesicles containing water channels with the apical membrane of receptor cells in the amphibian bladder and mammalian kidney. Fusion is accompanied by depolymerization of the actin cytoskeleton. In this review, we present the evidence for actin depolymerization by AVP in the whole cell, and the application of confocal microscopy and immunogold electron microscopy in localizing depolymerization to the apical region of the receptor cell.

Original languageEnglish (US)
Pages (from-to)672-679
Number of pages8
JournalPediatric Nephrology
Volume7
Issue number5
DOIs
StatePublished - Oct 1993

Fingerprint

Cytoskeleton
Vasopressins
Epithelial Cells
Aquaporins
Amphibians
Actin Cytoskeleton
Confocal Microscopy
Actins
Electron Microscopy
Urinary Bladder
Cell Membrane
Kidney

Keywords

  • Actin
  • Cytoskeleton
  • Urine concentration
  • Vasopressin

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

Cite this

The effect of vasopressin on the cytoskeleton of the epithelial cell. / Hays, Richard M.; Condeelis, John S.; Gao, Yang; Simon, Herold; Ding, Guohua; Franki, Nicholas.

In: Pediatric Nephrology, Vol. 7, No. 5, 10.1993, p. 672-679.

Research output: Contribution to journalArticle

Hays, Richard M. ; Condeelis, John S. ; Gao, Yang ; Simon, Herold ; Ding, Guohua ; Franki, Nicholas. / The effect of vasopressin on the cytoskeleton of the epithelial cell. In: Pediatric Nephrology. 1993 ; Vol. 7, No. 5. pp. 672-679.
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