The discovery of a highly selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson's Disease Model

Paolo Di Fruscia, Emmanouil Zacharioudakis, Chang Liu, Sébastien Moniot, Sasiwan Laohasinnarong, Mattaka Khongkow, Ian F. Harrison, Konstantina Koltsida, Christopher R. Reynolds, Karin Schmidtkunz, Manfred Jung, Kathryn L. Chapman, Clemens Steegborn, David T. Dexter, Michael J.E. Sternberg, Eric W.F. Lam, Matthew J. Fuchter